Medulloblastomas in Children
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Questions and Answers

What is the most common malignant childhood brain tumor?

  • Medulloblastoma (correct)
  • Glioblastoma
  • Astrocytoma
  • Meningioma

From which cell populations does medulloblastoma originate?

  • Late developmental cell populations
  • Early progenitor cell populations (correct)
  • Adult progenitor cells
  • Somatic stem cells

What are the four molecular subgroups of medulloblastoma described in the text?

  • WNT, SHH, Group 3, Group 4 (correct)
  • Ventral, dorsal, lateral, superior
  • Parietal, temporal, occipital, frontal
  • Epidermal, dermal, subdermal, mesodermal

What are the common signs and symptoms of medulloblastoma in children?

<p>Headache, nausea, and vomiting (A)</p> Signup and view all the answers

What is the purpose of postoperative adjuvant treatment for medulloblastoma?

<p>To perform risk-adapted craniospinal irradiation and chemotherapy (B)</p> Signup and view all the answers

Which of the following represents the embryonal tumor that originates from early progenitor cell populations present during early development?

<p>Medulloblastoma (B)</p> Signup and view all the answers

What are the distinct diseases with unique clinical and molecular features that medulloblastoma is composed of?

<p>SHH, Group 3, Wingless (WNT), and Group 4 (A)</p> Signup and view all the answers

What is the primary goal of postoperative adjuvant treatment for medulloblastoma?

<p>Preventing tumor recurrence (A)</p> Signup and view all the answers

What are the most common signs and symptoms that children with medulloblastoma often present with?

<p>Headache, nausea, and vomiting (C)</p> Signup and view all the answers

Who first described medulloblastoma as a posterior fossa tumor of childhood?

<p>Percival Bailey (C)</p> Signup and view all the answers

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