Medicinal Chemistry Unit I: Drug Design & Pharmacokinetics

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12 Questions

What is the primary goal of combinatorial synthesis in drug discovery?

To generate a large number of compounds to screen for activity

What is the primary mechanism of action of alkylating agents in cancer chemotherapy?

Inhibition of DNA replication

Which of the following pharmacokinetic parameters is used to determine the duration of drug action?

Half-life

What is the primary mode of action of direct-acting arteriolar dilators?

Relaxation of smooth muscle in arterioles

What is the primary mechanism of action of sulphonamides?

Inhibition of folic acid synthesis in bacteria

What is the primary goal of receptor site theory approach to drug design?

To design a drug that binds to a specific receptor

What is the primary function of B-lactam ring antibiotics?

Inhibiting cell wall biosynthesis

Which of the following drugs is NOT a CNS depressant?

Antibiotics

What is the name of the process by which Antipsychotic drugs, also known as neuroleptics, were discovered?

Serendipity

Which of the following books is NOT a suggested reading for Medical Chemistry?

The Organic Chemistry of Life, R.B.Silverrman

Which of the following drugs is synthesized from butyrophenones?

Haloperidol

What is the name of the process by which cell walls are formed in bacteria?

Cell wall biosynthesis

Test your knowledge of medicinal chemistry with this quiz covering drug design, structure-activity relationships, receptor site theory, pharmacokinetics, and antineoplastic agents. Assess your understanding of pharmacokinetic parameters, drug disposition, and their role in drug development.

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