Podcast
Questions and Answers
Which of the following is the zinc-binding moiety of ACE inhibitors?
Which of the following is the zinc-binding moiety of ACE inhibitors?
- Sulfhydryl (-SH) group
- Phosphoryl (-PO2) group
- Carboxylate
- Dicarboxylate (-COOH) group (correct)
What is the mechanism of action of AT2 antagonists?
What is the mechanism of action of AT2 antagonists?
- They activate the AT1 receptor
- They mimic the AT2 amino acid sequence (correct)
- They bind to the zinc component
- They inhibit the binding of Angiotensin II
Which class of calcium channel blockers is characterized by aromatic ring substitution?
Which class of calcium channel blockers is characterized by aromatic ring substitution?
- Non-dihydropyridines
- Diltiazem (correct)
- 1,4 Dihydropyridines
- Beta-blockers
Which position of the side-chain of the aryl ring determines the selectivity of beta-blockers?
Which position of the side-chain of the aryl ring determines the selectivity of beta-blockers?
Which of the following beta-blockers has the highest lipid solubility?
Which of the following beta-blockers has the highest lipid solubility?
Which group of drugs is classified as ACE inhibitors?
Which group of drugs is classified as ACE inhibitors?
What is the most important structure-function relationship of ACE inhibitors?
What is the most important structure-function relationship of ACE inhibitors?
Which factor contributes to the incomplete absorption of atenolol?
Which factor contributes to the incomplete absorption of atenolol?
Which beta-blocker is the most lipid-soluble and can readily penetrate the blood-brain barrier?
Which beta-blocker is the most lipid-soluble and can readily penetrate the blood-brain barrier?
Which factor contributes to the less predictable pharmacokinetics of atenolol during critical illness?
Which factor contributes to the less predictable pharmacokinetics of atenolol during critical illness?
Which type of alpha/beta blockers is Prazosin?
Which type of alpha/beta blockers is Prazosin?
Which beta-blocker has the highest tissue penetration?
Which beta-blocker has the highest tissue penetration?
Which factor is responsible for the higher tissue penetration of propanolol?
Which factor is responsible for the higher tissue penetration of propanolol?
Which beta-blocker has the shortest plasma half-life?
Which beta-blocker has the shortest plasma half-life?
Which factor contributes to the less predictable pharmacokinetics of atenolol during critical illness?
Which factor contributes to the less predictable pharmacokinetics of atenolol during critical illness?
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