Medical Parasitology Basics

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What is the function of a vector in the transmission of infections?

To complete the life cycle of the pathogen

Which type of vector is a housefly in the context of transmission of parasitic forms?

Mechanical vector

What does it mean for a living creature to be an intermediate host for a parasite?

It is essential in completing some parts of the parasite's life cycle

What distinguishes a biological vector from a mechanical vector?

The development and multiplication of the pathogenic organism in its body

What is the definition of a parasite?

An organism that is dependent on another organism for all of its life cycle and metabolic requirements

Which type of parasite is a helminth?

Macroparasite

What is the term for parasites that live on the surface of the host's body?

Ectoparasites

Which infectious agents are generally excluded from the term 'parasite'?

Viruses and bacteria

What does the pathogenicity of the infection depend on?

The resistance of the host and the state of nutrition

How can Entamoeba histolytica be differentiated from nonpathogenic amebae?

By molecular methods and immunologic analysis

What laboratory method is commonly used to diagnose E.histolytica in stool samples?

Microscopic identification using wet mount and permanently stained preparations

What may make an irritated intestine more susceptible to infection?

Drugs that irritate the intestinal wall

What symptoms may indicate the involvement of the olfactory lobes in the disease?

Disturbances in smell or taste

How long does the period between contact with the organism and onset of clinical symptoms typically vary?

7–15 days

What is a characteristic feature of the laboratory diagnosis of PAM using microscopy of CSF?

Demonstration of motile amoebae in simple wet-mount preparation

Why are almost all cases of PAM diagnosed during autopsies?

Because the disease progresses rapidly

How does Naegleria fowleri enter the human body?

Through inhalation into the nose

Where is Naegleria fowleri commonly found?

Industrial plant water discharges

What is the invasive stage of Naegleria fowleri in the human body?

Trophozoite (amoeboid) form

How is primary amoebic meningoencephalitis (PAM) caused by Naegleria fowleri transmitted to humans?

By inhalation of dust containing infective forms

What is the term for an association in which both host and parasite are so dependent upon each other that one cannot live without the help of the other?

Symbiosis

What is the term for an association in which only the parasite may benefit without detectable damage to the host?

Commensalism

What is the group of closely related species known as?

Genus

What is an agent, usually an insect, that transmits infection from one human host to another known as?

Vector

What is the characteristic motility of Trichomonas vaginalis trophozoite?

Whip-like and jerky

How does Chilomastix mesnili spread from one person to another?

Via contaminated water or food

Which medication is considered as effective as metronidazole for treating giardiasis?

Tinidazole

Where does Trichomonas vaginalis primarily inhabit in the human body?

Urinary bladder

What is the transmission stage of Giardia lamblia?

Cysts

Where do the trophozoites of Giardia lamblia primarily attach?

Jejunum

What may extremely large numbers of Giardia lamblia trophozoites lead to?

Nutrient uptake blockage

Which laboratory method can be used to detect anti-Giardia antibodies in patients' serum?

Enzyme-linked immunosorbent assay (ELISA)

What is the role of lipophosphoglycan (LPG) in the pathogenesis and evasion of host immunity?

It helps in the adhesion to host cells

How are symptoms of trichomoniasis different in infected females and males?

Females experience dysuria and low abdominal discomfort, while males are usually asymptomatic

What is the most traditional method for the laboratory diagnosis of trichomoniasis?

Microscopic examination

Why is it challenging to diagnose T. vaginalis based solely on classic symptoms?

Because the symptoms are synonymous with those of other STDs

What is the transmission stage of Giardia lamblia?

Cysts

Where do the trophozoites of Giardia lamblia primarily attach?

Jejunum

What symptoms may extremely large numbers of Giardia lamblia trophozoites lead to?

Severe diarrhea of steatorrhoea type

How is Giardia lamblia transmitted to humans?

Through contaminated water and food

Which antibiotic can often treat giardiasis in a single dose and is as effective as metronidazole?

Tinidazole

Which parasite inhabits the human urogenital tract and is responsible for trichomoniasis?

Trichomonas vaginalis

What is the resistant cyst stage in the life cycle of Chilomastix mesnili responsible for?

Transmission

How many flagella does Trichomonas vaginalis trophozoite have?

5

What are the symptoms of trichomoniasis in females?

Vaginal discharge, irritation, and low abdominal discomfort

What is the primary method for laboratory diagnosis of trichomoniasis?

Microscopic examination

What is the role of infected males in trichomoniasis?

They are usually asymptomatic carriers of infection

What type of antibiotics are commonly used to treat trichomoniasis?

Nitroimidazole antibiotics

What is the primary method of transmission for Leishmaniasis?

Sandfly bites

In which hosts is the life cycle of Leishmania completed?

Humans and sandflies

What is the term 'New World' used to refer to in the context of Leishmaniasis?

The Americas

What is the natural reservoir host for Leishmania?

Humans, dogs, and wild rodents

Where do the amastigotes replicate in the human body?

In the reticuloendothelial cells of the skin

What can cause an open sore at the bite sites in cutaneous leishmaniasis?

Presence of L.tropica, L.major, L.aethiopica

What is the main habitat of diffuse cutaneous leishmaniasis?

Inside reticuloendothelial cells of the skin

What is the main route for transmission of Leishmaniasis to a new host?

Migration to fresh cells in the skin

What is the secondary form of kala-azar called?

Post kala-azar dermal leishmaniasis

What is the cause of PKDL?

Reversal of L.donovani from viscerotropic to dermatotropic

Which test is negative in active cases of kala-azar due to impaired cell-mediated immunity?

Leishmanin test

How can the diagnosis of PKDL be established?

Visualization of amastigotes in splenic or bone marrow aspirate

Test your knowledge of the fundamental concepts in medical parasitology with this quiz. Learn about parasites, their life cycles, diseases they cause, and methods of diagnosis, prevention, and treatment.

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