Medical Biology and Pain Management Quiz
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Questions and Answers

Which of the following statements regarding opioids is accurate?

  • Opioids are non-controlled substances.
  • Morphine is considered the prototypical opioid. (correct)
  • Opioids primarily act as anti-inflammatory agents.
  • Opioids do not cause any significant side effects.
  • What is a potential complication associated with prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs)?

  • Prolonged sedation
  • Excessive weight gain
  • Neuropathic pain
  • Stomach ulcers (correct)
  • In the context of cancer pain, which factor is NOT typically responsible for the pain experienced by patients?

  • Enzymatic destruction of adjacent tissues
  • Inflammatory mediators released during treatment
  • Tumors applying pressure on tissues
  • Stable bone structure (correct)
  • Which condition is characterized by the sensation of numbness and tingling down the leg, particularly affecting the sciatic nerve?

    <p>Spinal nerve radiculopathy (B)</p> Signup and view all the answers

    Which of the following adjuvant medications is commonly known for its use in local pain relief?

    <p>Lidocaine (B)</p> Signup and view all the answers

    What is the primary function of proteasomes in cellular biology?

    <p>Degrade proteins and polypeptide chains (B)</p> Signup and view all the answers

    What condition arises from dysfunction of peroxisomes?

    <p>Adrenoleukodystrophy (D)</p> Signup and view all the answers

    What is the role of the Golgi apparatus in the cell?

    <p>Process, package, and secrete proteins (C)</p> Signup and view all the answers

    Which statement is true about the smooth endoplasmic reticulum?

    <p>It is involved in the production of corticosteroids and phospholipids. (B)</p> Signup and view all the answers

    What do microtubules assist with in a cell?

    <p>Cell division and intracellular transport (C)</p> Signup and view all the answers

    How does the sodium-potassium pump maintain resting membrane potential?

    <p>By using ATP to actively transport sodium out and potassium into the cell (C)</p> Signup and view all the answers

    Which of the following components is primarily responsible for the synthesis of new proteins?

    <p>Ribosomes (B)</p> Signup and view all the answers

    What is a common consequence of the drop in blood pressure when moving from a resting position to standing?

    <p>Dizziness and weakness (D)</p> Signup and view all the answers

    At which stage of pressure sores is there a loss of full thickness of tissue, down to muscle and bone?

    <p>Stage IV (D)</p> Signup and view all the answers

    Which guideline is NOT recommended for repositioning patients on bed rest?

    <p>Leave the patient in one position for comfort (B)</p> Signup and view all the answers

    Where is the risk of ulcer formation highest?

    <p>Bony prominences such as heels and sacrum (A)</p> Signup and view all the answers

    Which adipokine is known for increasing insulin sensitivity?

    <p>Adiponectin (D)</p> Signup and view all the answers

    What effect does leptin have on the body?

    <p>Signals fullness (C)</p> Signup and view all the answers

    Which adipokine is associated with increased insulin resistance, particularly in obese individuals?

    <p>Resistin (C)</p> Signup and view all the answers

    Elevated levels of angiotensinogen can lead to which condition?

    <p>Hypertension and arteriosclerosis (D)</p> Signup and view all the answers

    Which of the following best describes resistin?

    <p>A mediator that decreases insulin sensitivity (A)</p> Signup and view all the answers

    What is the effect of increased adiposity on the secretion of adipokines?

    <p>Increases both beneficial and harmful hormones (D)</p> Signup and view all the answers

    What is the primary role of modulation in the pain transmission process?

    <p>It alters the perception of pain by afferent neurons. (A)</p> Signup and view all the answers

    Which statement best describes neuropathic pain?

    <p>It results from abnormal signals in the spinal cord or peripheral nerves. (D)</p> Signup and view all the answers

    How does acute pain differ from chronic pain?

    <p>Acute pain arises from new injuries, whereas chronic pain is linked to long-term conditions. (B)</p> Signup and view all the answers

    What is the main function of the neuromatrix in the pain experience?

    <p>To generate pain independent of nociceptive stimulation. (C)</p> Signup and view all the answers

    Which of the following best describes phantom limb pain?

    <p>Pain felt in an amputated limb stemming from the brain's interpretation of nerve signals. (B)</p> Signup and view all the answers

    Which factors can influence an individual's perception of pain?

    <p>Personal experiences and emotional state. (A)</p> Signup and view all the answers

    What distinguishes noceptive pain from other forms of pain?

    <p>It arises from actual tissue injury and serves a protective function. (C)</p> Signup and view all the answers

    What is the likely cause of chronic pain in diseases like rheumatoid arthritis?

    <p>It persists due to ongoing inflammation and does not fulfill protective purposes. (B)</p> Signup and view all the answers

    What role does the dorsal horn play in the pain transmission process?

    <p>It serves as a primary processing area for incoming pain signals. (A)</p> Signup and view all the answers

    What can lead to the generation of pain apart from nociceptive stimulation?

    <p>Genetic predispositions and chronic stress. (C)</p> Signup and view all the answers

    What is the primary difference between Apoptosis and Necrosis in terms of the body's response?

    <p>Necrosis causes inflammation, whereas Apoptosis does not. (C)</p> Signup and view all the answers

    What is the primary cause of hypertension, as described in the text?

    <p>Hypertension can be caused by epithelial injury, atherosclerosis, and weakened arterial walls. (D)</p> Signup and view all the answers

    How does the text describe the link between hormone production and cardiovascular health?

    <p>Lack of hormone production leads to reduced angiogenesis, which can contribute to heart disease. (C)</p> Signup and view all the answers

    What is the primary effect of endothelin on blood vessels?

    <p>Endothelin causes blood vessels to constrict, decreasing blood flow. (A)</p> Signup and view all the answers

    Which of the following is NOT a possible consequence of untreated hypertension?

    <p>Decreased risk of stroke. (A)</p> Signup and view all the answers

    What is the direct link between diabetes (DM) and endothelial function, as described in the text?

    <p>Diabetes can cause the endothelium to release endothelin, a powerful vasoconstrictor, contributing to atherosclerosis. (D)</p> Signup and view all the answers

    What role do 'introns' play in the production of proteins?

    <p>Introns are non-coding sections of DNA that are removed during RNA processing. (B)</p> Signup and view all the answers

    What is the difference between 'genetics' and 'genomics'?

    <p>Genetics studies the inheritance of genes, while genomics studies the interaction of all genetic material within an organism. (B)</p> Signup and view all the answers

    In the context of DNA structure, what is the function of a nucleotide?

    <p>Nucleotide is the basic unit of DNA consisting of a sugar, phosphate, and nitrogen base. (C)</p> Signup and view all the answers

    Flashcards

    Proteasomes

    Cell structures that degrade proteins and polypeptides, important in muscle wasting conditions.

    Peroxisomes

    Organelles that degrade free radicals and long-chain fatty acids; dysfunction can lead to diseases.

    Smooth ER

    Endoplasmic reticulum involved in lipid production including corticosteroids and phospholipids.

    Rough ER

    Endoplasmic reticulum with ribosomes that synthesizes proteins.

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    Golgi apparatus

    Processes and packages proteins, involved in hormone creation such as insulin.

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    Nucleus

    The cell's command center that contains DNA and regulates activities.

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    Sodium-potassium pump

    Transport mechanism that maintains cell membrane potential using ATP; crucial for fluid balance.

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    Angiogenesis

    The process of forming new blood vessels in the body.

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    Ischemia

    A condition characterized by insufficient blood supply to tissues, often leading to damage.

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    Hypertension

    Elevated blood pressure that can lead to serious health issues if untreated.

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    Cardiovascular diseases

    A group of diseases related to the heart and blood vessels, leading to complications.

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    Apoptosis

    Programmed cell death that occurs naturally without causing inflammation.

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    Necrosis

    Unplanned cell death caused by factors like injury or stress, leading to tissue damage.

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    Endothelin

    A potent vasoconstrictor produced by endothelial cells that narrows blood vessels.

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    Apoptosis vs Necrosis

    Apoptosis is natural cell death, while necrosis is unplanned and leads to inflammation.

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    DNA Nucleotide

    The basic building block of DNA, comprising a sugar, phosphate, and nitrogen base.

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    Postural Hypotension

    A drop in blood pressure when standing, causing dizziness or weakness.

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    Risk of Falls

    The increased danger of falling due to dizziness or weakness.

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    Pressure Ulcer Stage I

    Persistent skin redness without skin breakdown.

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    Pressure Ulcer Stage II

    Loss of epidermal or dermal layers, with blisters or abrasions.

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    Pressure Ulcer Stage III

    Deterioration of layers below the dermis, exposing fat.

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    Pressure Ulcer Stage IV

    Complete loss of skin thickness down to muscle or bone.

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    Repositioning Guidelines

    Patients must be rotated and evaluated every 2 hours.

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    Bony Prominences

    Areas most likely to develop pressure ulcers, such as heels or elbows.

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    Adipocytes

    Fat cells that secrete hormones affecting metabolism.

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    Leptin

    A hormone that regulates appetite and energy expenditure.

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    Opioids

    Controlled substances that relieve pain but may cause euphoria and sedation.

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    Nonopioid analgesics

    Medications like acetaminophen and NSAIDs used for pain relief without addictive properties.

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    Cancer pain

    Pain caused by tumors affecting surrounding structures or by treatments like chemotherapy.

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    Spinal nerve radiculopathy

    A condition where spinal nerves are compressed, often causing pain that radiates down the legs.

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    Diabetic Peripheral Neuropathy

    Nerve damage due to high glucose levels, affecting both sensory and motor functions.

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    Pain transmission

    The process of nerve impulses carrying pain signals from injury site to the brain.

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    Pain modulation

    The impact of interneurons on pain signals, either amplifying or dampening pain experience.

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    Pain perception

    The conscious awareness and interpretation of pain, influenced by personal experiences and mental state.

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    Phantom limb pain

    Pain that feels as though it is coming from a limb that has been amputated, reported in 70% of amputees.

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    Neuromatrix theory

    A theory suggesting that pain is generated from a body-self neuromatrix in the brain, independent of physical injury.

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    Acute pain

    A sudden pain typically lasting hours to days due to tissue injury or inflammation, resolving with healing.

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    Chronic pain

    Pain lasting longer than 6 months, often due to persistent inflammation, with no useful biological function.

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    Neuropathic pain

    Pain caused by injury to nerves, characterized by sensations like burning or tingling; can occur randomly.

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    Nociceptive pain

    Pain resulting from tissue injury that signals damage, typically providing an important protective function.

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    Types of pain

    Includes acute, chronic, and neuropathic pain, each differing in cause, duration, and sensation.

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