Medical Biology and Pain Management Quiz

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Questions and Answers

Which of the following statements regarding opioids is accurate?

  • Opioids are non-controlled substances.
  • Morphine is considered the prototypical opioid. (correct)
  • Opioids primarily act as anti-inflammatory agents.
  • Opioids do not cause any significant side effects.

What is a potential complication associated with prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs)?

  • Prolonged sedation
  • Excessive weight gain
  • Neuropathic pain
  • Stomach ulcers (correct)

In the context of cancer pain, which factor is NOT typically responsible for the pain experienced by patients?

  • Enzymatic destruction of adjacent tissues
  • Inflammatory mediators released during treatment
  • Tumors applying pressure on tissues
  • Stable bone structure (correct)

Which condition is characterized by the sensation of numbness and tingling down the leg, particularly affecting the sciatic nerve?

<p>Spinal nerve radiculopathy (B)</p> Signup and view all the answers

Which of the following adjuvant medications is commonly known for its use in local pain relief?

<p>Lidocaine (B)</p> Signup and view all the answers

What is the primary function of proteasomes in cellular biology?

<p>Degrade proteins and polypeptide chains (B)</p> Signup and view all the answers

What condition arises from dysfunction of peroxisomes?

<p>Adrenoleukodystrophy (D)</p> Signup and view all the answers

What is the role of the Golgi apparatus in the cell?

<p>Process, package, and secrete proteins (C)</p> Signup and view all the answers

Which statement is true about the smooth endoplasmic reticulum?

<p>It is involved in the production of corticosteroids and phospholipids. (B)</p> Signup and view all the answers

What do microtubules assist with in a cell?

<p>Cell division and intracellular transport (C)</p> Signup and view all the answers

How does the sodium-potassium pump maintain resting membrane potential?

<p>By using ATP to actively transport sodium out and potassium into the cell (C)</p> Signup and view all the answers

Which of the following components is primarily responsible for the synthesis of new proteins?

<p>Ribosomes (B)</p> Signup and view all the answers

What is a common consequence of the drop in blood pressure when moving from a resting position to standing?

<p>Dizziness and weakness (D)</p> Signup and view all the answers

At which stage of pressure sores is there a loss of full thickness of tissue, down to muscle and bone?

<p>Stage IV (D)</p> Signup and view all the answers

Which guideline is NOT recommended for repositioning patients on bed rest?

<p>Leave the patient in one position for comfort (B)</p> Signup and view all the answers

Where is the risk of ulcer formation highest?

<p>Bony prominences such as heels and sacrum (A)</p> Signup and view all the answers

Which adipokine is known for increasing insulin sensitivity?

<p>Adiponectin (D)</p> Signup and view all the answers

What effect does leptin have on the body?

<p>Signals fullness (C)</p> Signup and view all the answers

Which adipokine is associated with increased insulin resistance, particularly in obese individuals?

<p>Resistin (C)</p> Signup and view all the answers

Elevated levels of angiotensinogen can lead to which condition?

<p>Hypertension and arteriosclerosis (D)</p> Signup and view all the answers

Which of the following best describes resistin?

<p>A mediator that decreases insulin sensitivity (A)</p> Signup and view all the answers

What is the effect of increased adiposity on the secretion of adipokines?

<p>Increases both beneficial and harmful hormones (D)</p> Signup and view all the answers

What is the primary role of modulation in the pain transmission process?

<p>It alters the perception of pain by afferent neurons. (A)</p> Signup and view all the answers

Which statement best describes neuropathic pain?

<p>It results from abnormal signals in the spinal cord or peripheral nerves. (D)</p> Signup and view all the answers

How does acute pain differ from chronic pain?

<p>Acute pain arises from new injuries, whereas chronic pain is linked to long-term conditions. (B)</p> Signup and view all the answers

What is the main function of the neuromatrix in the pain experience?

<p>To generate pain independent of nociceptive stimulation. (C)</p> Signup and view all the answers

Which of the following best describes phantom limb pain?

<p>Pain felt in an amputated limb stemming from the brain's interpretation of nerve signals. (B)</p> Signup and view all the answers

Which factors can influence an individual's perception of pain?

<p>Personal experiences and emotional state. (A)</p> Signup and view all the answers

What distinguishes noceptive pain from other forms of pain?

<p>It arises from actual tissue injury and serves a protective function. (C)</p> Signup and view all the answers

What is the likely cause of chronic pain in diseases like rheumatoid arthritis?

<p>It persists due to ongoing inflammation and does not fulfill protective purposes. (B)</p> Signup and view all the answers

What role does the dorsal horn play in the pain transmission process?

<p>It serves as a primary processing area for incoming pain signals. (A)</p> Signup and view all the answers

What can lead to the generation of pain apart from nociceptive stimulation?

<p>Genetic predispositions and chronic stress. (C)</p> Signup and view all the answers

What is the primary difference between Apoptosis and Necrosis in terms of the body's response?

<p>Necrosis causes inflammation, whereas Apoptosis does not. (C)</p> Signup and view all the answers

What is the primary cause of hypertension, as described in the text?

<p>Hypertension can be caused by epithelial injury, atherosclerosis, and weakened arterial walls. (D)</p> Signup and view all the answers

How does the text describe the link between hormone production and cardiovascular health?

<p>Lack of hormone production leads to reduced angiogenesis, which can contribute to heart disease. (C)</p> Signup and view all the answers

What is the primary effect of endothelin on blood vessels?

<p>Endothelin causes blood vessels to constrict, decreasing blood flow. (A)</p> Signup and view all the answers

Which of the following is NOT a possible consequence of untreated hypertension?

<p>Decreased risk of stroke. (A)</p> Signup and view all the answers

What is the direct link between diabetes (DM) and endothelial function, as described in the text?

<p>Diabetes can cause the endothelium to release endothelin, a powerful vasoconstrictor, contributing to atherosclerosis. (D)</p> Signup and view all the answers

What role do 'introns' play in the production of proteins?

<p>Introns are non-coding sections of DNA that are removed during RNA processing. (B)</p> Signup and view all the answers

What is the difference between 'genetics' and 'genomics'?

<p>Genetics studies the inheritance of genes, while genomics studies the interaction of all genetic material within an organism. (B)</p> Signup and view all the answers

In the context of DNA structure, what is the function of a nucleotide?

<p>Nucleotide is the basic unit of DNA consisting of a sugar, phosphate, and nitrogen base. (C)</p> Signup and view all the answers

Flashcards

Proteasomes

Cell structures that degrade proteins and polypeptides, important in muscle wasting conditions.

Peroxisomes

Organelles that degrade free radicals and long-chain fatty acids; dysfunction can lead to diseases.

Smooth ER

Endoplasmic reticulum involved in lipid production including corticosteroids and phospholipids.

Rough ER

Endoplasmic reticulum with ribosomes that synthesizes proteins.

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Golgi apparatus

Processes and packages proteins, involved in hormone creation such as insulin.

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Nucleus

The cell's command center that contains DNA and regulates activities.

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Sodium-potassium pump

Transport mechanism that maintains cell membrane potential using ATP; crucial for fluid balance.

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Angiogenesis

The process of forming new blood vessels in the body.

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Ischemia

A condition characterized by insufficient blood supply to tissues, often leading to damage.

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Hypertension

Elevated blood pressure that can lead to serious health issues if untreated.

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Cardiovascular diseases

A group of diseases related to the heart and blood vessels, leading to complications.

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Apoptosis

Programmed cell death that occurs naturally without causing inflammation.

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Necrosis

Unplanned cell death caused by factors like injury or stress, leading to tissue damage.

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Endothelin

A potent vasoconstrictor produced by endothelial cells that narrows blood vessels.

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Apoptosis vs Necrosis

Apoptosis is natural cell death, while necrosis is unplanned and leads to inflammation.

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DNA Nucleotide

The basic building block of DNA, comprising a sugar, phosphate, and nitrogen base.

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Postural Hypotension

A drop in blood pressure when standing, causing dizziness or weakness.

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Risk of Falls

The increased danger of falling due to dizziness or weakness.

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Pressure Ulcer Stage I

Persistent skin redness without skin breakdown.

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Pressure Ulcer Stage II

Loss of epidermal or dermal layers, with blisters or abrasions.

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Pressure Ulcer Stage III

Deterioration of layers below the dermis, exposing fat.

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Pressure Ulcer Stage IV

Complete loss of skin thickness down to muscle or bone.

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Repositioning Guidelines

Patients must be rotated and evaluated every 2 hours.

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Bony Prominences

Areas most likely to develop pressure ulcers, such as heels or elbows.

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Adipocytes

Fat cells that secrete hormones affecting metabolism.

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Leptin

A hormone that regulates appetite and energy expenditure.

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Opioids

Controlled substances that relieve pain but may cause euphoria and sedation.

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Nonopioid analgesics

Medications like acetaminophen and NSAIDs used for pain relief without addictive properties.

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Cancer pain

Pain caused by tumors affecting surrounding structures or by treatments like chemotherapy.

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Spinal nerve radiculopathy

A condition where spinal nerves are compressed, often causing pain that radiates down the legs.

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Diabetic Peripheral Neuropathy

Nerve damage due to high glucose levels, affecting both sensory and motor functions.

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Pain transmission

The process of nerve impulses carrying pain signals from injury site to the brain.

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Pain modulation

The impact of interneurons on pain signals, either amplifying or dampening pain experience.

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Pain perception

The conscious awareness and interpretation of pain, influenced by personal experiences and mental state.

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Phantom limb pain

Pain that feels as though it is coming from a limb that has been amputated, reported in 70% of amputees.

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Neuromatrix theory

A theory suggesting that pain is generated from a body-self neuromatrix in the brain, independent of physical injury.

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Acute pain

A sudden pain typically lasting hours to days due to tissue injury or inflammation, resolving with healing.

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Chronic pain

Pain lasting longer than 6 months, often due to persistent inflammation, with no useful biological function.

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Neuropathic pain

Pain caused by injury to nerves, characterized by sensations like burning or tingling; can occur randomly.

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Nociceptive pain

Pain resulting from tissue injury that signals damage, typically providing an important protective function.

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Types of pain

Includes acute, chronic, and neuropathic pain, each differing in cause, duration, and sensation.

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