Mechanism of Photoreception

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Questions and Answers

What is the primary reason the rod cells release neurotransmitter in complete darkness?

  • The Na$^+$ pump is continuously pumping out Na$^+. (correct)
  • Light hits the retina, stimulating cones.
  • The Na$^+$ channels are closed.
  • Rhodopsin is inactive.

What occurs in rod cells when light hits the retina?

  • Hyperpolarisation reduces neurotransmitter release. (correct)
  • Trans-retinal activates rhodopsin to open Na$^+$ channels.
  • Bipolar cells are inhibited, preventing action potentials.
  • Na$^+$ channels open to allow depolarisation.

During dark adaptation, what happens to rhodopsin as the eyes adjust to darkness?

  • It continuously produces trans-retinal.
  • All rods adapt in less than 10 minutes.
  • It becomes less sensitive to light.
  • Cis-retinal accumulates, increasing sensitivity. (correct)

How does the content of neurotransmitter release from rod cells change in response to light?

<p>It decreases in bright light due to hyperpolarisation. (D)</p> Signup and view all the answers

Which process explains the changing permeability of the rod cell membrane during dark adaptation?

<p>Rhodopsin transforms to close Na$^+$ channels. (B)</p> Signup and view all the answers

What is the effect of the bipolar neuron when it receives decreased neurotransmitter from the rod in dim light?

<p>It becomes depolarised and generates an action potential. (B)</p> Signup and view all the answers

What is the consequence of neurotransmitter release at the synapse between the rod cell and bipolar cell in complete darkness?

<p>It hyperpolarises the bipolar cell preventing action potential. (D)</p> Signup and view all the answers

What happens to the Na$^+$ channels in rods when they are bleached during light exposure?

<p>They close, reducing Na$^+$ permeability. (C)</p> Signup and view all the answers

What is the role of retinal in the composition of rhodopsin?

<p>It acts as a photosensitive compound that undergoes a change in light. (B)</p> Signup and view all the answers

What occurs to rhodopsin when it is exposed to bright light?

<p>It undergoes a process known as bleaching. (D)</p> Signup and view all the answers

What is the isomerization process of retinal when light is involved?

<p>Cis-retinal converts to trans-retinal. (B)</p> Signup and view all the answers

How long does it take for trans-retinal to be converted back to cis-retinal?

<p>A few minutes. (C)</p> Signup and view all the answers

What happens to rods in bright light conditions?

<p>They become saturated and unresponsive. (A)</p> Signup and view all the answers

Which statement correctly describes the relationship between opsin and retinal in rhodopsin?

<p>Retinal forms a strong covalent bond with opsin. (B)</p> Signup and view all the answers

What is the result of the bleaching process in rhodopsin?

<p>Rhodopsin loses its ability to respond to light stimuli. (B)</p> Signup and view all the answers

Which structural change occurs in rhodopsin upon absorbing a photon of light?

<p>Retinal undergoes a conformational change. (A)</p> Signup and view all the answers

Flashcards

Rhodopsin

A conjugated protein found in rods of the retina that absorbs light and initiates the process of phototransduction.

Retinal

A light-absorbing carotenoid molecule derived from vitamin A that's part of rhodopsin.

Opsin

The protein component of rhodopsin.

Photoisomerization

A change in the shape of retinal from cis-retinal to trans-retinal due to light absorption.

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Bleaching

The process of rhodopsin breaking down into retinal and opsin after absorbing light.

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Photosensitivity

The state in which rhodopsin is unable to respond to light after being bleached.

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Rhodopsin Regeneration

The conversion of trans-retinal back to cis-retinal in the dark, allowing rhodopsin to regenerate.

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Dark Adaptation

The reason why you are initially blind when entering a dark room from bright light.

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Hyperpolarization of the Rod

The process of the rod cell becoming more negative in charge, triggered by light exposure, which reduces neurotransmitter release.

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Inhibitory Synapse

A type of synapse where the neurotransmitter released by the presynaptic neuron inhibits the postsynaptic neuron.

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Excitatory Synapse

A type of synapse where the neurotransmitter released by the presynaptic neuron excites the postsynaptic neuron, promoting a signal.

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Depolarization of the Rod

The process of the rod cell becoming less negative in charge, triggered by darkness, leading to increased neurotransmitter release.

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Rod Cell Depolarization in Darkness

In the dark, rhodopsin with cis-retinal opens Na+ channels in the outer segment of the rod, allowing Na+ to flow in, depolarizing the cell.

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Rod Cell Hyperpolarization in Light

Light changes rhodopsin to trans-retinal, closing Na+ channels. This reduces Na+ influx, leading to hyperpolarization of the rod cell.

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Study Notes

Mechanism of Photoreception

  • Rods contain the pigment rhodopsin
  • Rhodopsin is formed by the combination of:
    • A light-absorbing carotenoid molecule called retinal (retine)
    • A protein called opsin
  • Retinal exists in two isomeric forms:
    • cis form (in dark)
    • trans form (in light)
  • When a rod cell is exposed to light, light causes the retinal molecule to change from its cis form into a trans form
  • This change puts strain on the molecule and the bond between retinal and opsin is broken
  • This causes the rod cell to bleach
  • enzymes convert trans-retinal to the original cis-retinal in the dark
  • This process takes a few minutes
  • In dim light, rhodopsin is bleached
  • In bright light, rhodopsin is bleached, and rods lose their photosensitivity

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