Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

18 Questions

2 Views

Mechanism of Action of β-Lactams

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the mechanism of action of β-lactam antibiotics?

Inhibit protein synthesis in bacteria

Inhibit DNA synthesis in bacteria

Prevent cross-linking of the cell wall by binding to PBPs (correct)

Prevent mRNA transcription in bacteria

How do bacteria develop resistance to β-lactam antibiotics?

Increasing mRNA stability

Enhancing DNA replication

Overproduction of β-lactamases (correct)

Reducing cell wall thickness

Which type of bacteria are β-lactam antibiotics most effective against?

Stationary phase bacteria

Mature biofilm bacteria

Non-dividing bacteria

Multiplying (growing) cells (correct)

What is the main adverse effect associated with monobactams?

Allergic reactions Signup and view all the answers

How do bacteria reduce the intracellular concentration of β-lactam antibiotics in Gram-negative organisms?

Modifying porins Signup and view all the answers

Which bacterial resistance mechanism involves the formation of new types of PBPs like PBP2a in S.aureus?

Formation of new PBPs Signup and view all the answers

Which type of bacteria is Piperacillin most active against?

Gram-negative bacteria Signup and view all the answers

What is a unique feature of Ceftaroline among cephalosporins?

Activity against MRSA Signup and view all the answers

Which generation of cephalosporins can penetrate the blood-brain barrier?

3rd generation Signup and view all the answers

What is the advantage of Aztreonam among monobactams?

Low allergic reactions Signup and view all the answers

Which bacteria are cephalosporins generally not active against?

Bacteroides Signup and view all the answers

Why is Piperacillin considered a prodrug?

It is inactive until metabolized in the body Signup and view all the answers

Which type of inhibitor is Avibactam?

β-lactamase stable inhibitor Signup and view all the answers

What is the mechanism of action of isoxazolylpenicillins regarding β lactamase?

They form reversible complexes with β lactamase Signup and view all the answers

Which compound is used in combination with Amoxicillin as co-amoxiclav?

Clavulanic acid Signup and view all the answers

Which inhibitor forms an unstable complex with β lactamase that dissociates into broken inhibitor & broken enzyme?

Sulbactam Signup and view all the answers

Which combination is used for treating complicated urinary tract infections and pyelonephritis?

Avibactam with meropenem Signup and view all the answers

Which of the following inhibitors is not absorbed orally and is only available in injection form?

Tazobactam Signup and view all the answers