Mechanism of Action of Local Anesthesia
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Questions and Answers

What factor affects the onset of action of a local anesthetic used in oral surgery?

  • The amount of drug removed by local blood vessels
  • Proximity to the target nerve (correct)
  • Duration of action
  • Type of vasoconstrictor added

Why are vasoconstrictors added to local anesthetics for oral surgery?

  • To prolong the duration by dampening the effects of local vessels on drug removal (correct)
  • To speed up the onset of action
  • To reduce the amount of drug deposited
  • To increase the pH of the solution

Which anesthesia lasts a shorter time: pulpal anesthesia of maxillary teeth after local infiltration or pulpal anesthesia of mandibular teeth after block anesthesia?

  • Maxillary teeth after local infiltration (correct)
  • Mandibular teeth after block anesthesia
  • There is no difference in duration
  • Both last for the same duration

How does the amount of drug deposited affect the duration of action of a local anesthetic?

<p>More drug deposited leads to longer duration (C)</p> Signup and view all the answers

What is the role of vascularity of tissue in the duration of action of a local anesthetic?

<p>Low vascularity prolongs duration (C)</p> Signup and view all the answers

Why does pulpal anesthesia disappear earlier than soft tissue anesthesia in some cases?

<p>Deposition closer to soft tissues than to pulp (D)</p> Signup and view all the answers

What is the purpose of local anesthesia in dentistry?

<p>To block the function of sensory nerves (D)</p> Signup and view all the answers

Why is it optimal to limit the number of different forms of a drug used by those administering local anesthesia?

<p>To master the use of a specific category of drug (C)</p> Signup and view all the answers

In local anesthesia, which ions are allowed to shift across the nerve membrane upon depolarization?

<p>Sodium ions (A)</p> Signup and view all the answers

How does local anesthesia affect motor nerves?

<p>It inhibits their function (C)</p> Signup and view all the answers

What is a paradoxical effect in relation to drug reactions?

<p>An opposite outcome of a drug occurs (C)</p> Signup and view all the answers

What is the main goal in properly performing oral surgery on an awake patient?

<p>To provide profound local anesthesia (B)</p> Signup and view all the answers

What is the primary mechanism of action of local anesthetics?

<p>Raising the membrane firing threshold for electric impulse propagation (C)</p> Signup and view all the answers

At what pH do local anesthetics without vasoconstrictors typically work best?

<p>pH 6.5 (C)</p> Signup and view all the answers

Why do manufacturers lower the pH of local anesthetics when adding vasoconstrictive agents like epinephrine?

<p>To inhibit oxidation of the vasoconstrictor (D)</p> Signup and view all the answers

What effect does local anesthetic pH have on its effectiveness when injected into an area of inflammation/infection?

<p>It becomes less effective (C)</p> Signup and view all the answers

How do local anesthetics primarily affect nerve membranes to prevent impulse conduction?

<p>Maintaining a depolarized state (C)</p> Signup and view all the answers

What factor influences the speed of onset and duration of action of local anesthetics?

<p>Their lipid solubility (D)</p> Signup and view all the answers

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