Mbacet: Synthetic Cannabinoid Overview

Overview of Mbacet

• Mbacet is also known as 1-(1-Naphthyl)ethylideneindene.
• It is a synthetic cannabinoid derived from JWH-018.
• Mbacet is a relatively new substance, and its pharmacology remains not well understood.
• It is structurally related to synthetic cannabinoids like JWH-018 and AM-2201.
• The molecular formula is C21H16, with a molecular weight of 268.35 g/mol.
• It typically appears as a white to off-white crystalline solid.
• Mbacet is a research chemical

Pharmacology

• Mbacet is a potent full agonist of the CB1 receptor, displaying high binding affinity.
• It is more potent than JWH-018 in some studies.
• It also binds to the CB2 receptor, but with less potency than at the CB1 receptor.
• Animal studies indicate that Mbacet induces typical cannabinoid effects such as hypothermia, analgesia, and catalepsy.
• Little data is available regarding the metabolism.
• It is metabolized in the liver by cytochrome P450 enzymes.
• Metabolites of Mbacet are not well characterized.
• It is excreted in the urine and feces.
• The half-life of Mbacet is unknown.

Detection and Analysis

• Mbacet can be detected in seized drug samples.
• Analytical methods for detection include gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS).
• The impurity profiles of Mbacet are often complex, complicating its identification and quantification in seized samples.
• It is a relatively stable compound and can be stored for extended periods without significant degradation.

Synthesis and Availability

• The synthesis of Mbacet involves several steps.
• It can be synthesized from readily available chemicals, making its production and distribution difficult to control.
• Mbacet has been identified in herbal mixtures.
• It is often sold as a powder or in herbal mixtures and is frequently mislabeled as a different substance.
• It is also known under other street names, which vary regionally.
• Mbacet is often marketed as a "legal high", despite being illegal in many jurisdictions.

Legal Status

• Mbacet is considered a controlled substance in some jurisdictions.
• It is a Schedule I controlled substance in the United States, with no accepted medical use.
• The legal status of Mbacet varies from country to country.
• It is banned in many countries.
• Mbacet is considered a new psychoactive substance (NPS).
• NPS are substances designed to mimic the effects of traditional drugs of abuse.

Recreational Use and Health Risks

• It is used recreationally for its psychoactive effects
• Mbacet poses potential health risks.
• It may cause anxiety, paranoia, and hallucinations.
• Animal studies exploring the pharmacological effects are limited.
• Public health agencies have issued warnings about the dangers of Mbacet.
• Overdose may result in serious adverse effects, including seizures, respiratory depression, and coma.
• Treatment for Mbacet overdose is supportive, as there is no specific antidote.
• It is typically smoked or ingested.
• The dosage varies depending on the individual and the route of administration.
• Its use is associated with several deaths.
• Mbacet is a dangerous substance and should be avoided.
• It is part of a larger class of synthetic cannabinoids, which are a growing concern for public health officials.
• The long-term effects of Mbacet use are unknown.
• It poses a significant risk to public health, and its use should be discouraged.
• More research is needed to fully understand the pharmacology and toxicology of Mbacet.