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Questions and Answers
Worldwide, alcohol-related deaths account for approximately 25% of all fatalities in the 20-39 age group.
Worldwide, alcohol-related deaths account for approximately 25% of all fatalities in the 20-39 age group.
True (A)
In the context of alcohol dependence, ICD-10 criteria emphasize sociological aspects of dependence rather than physical ones.
In the context of alcohol dependence, ICD-10 criteria emphasize sociological aspects of dependence rather than physical ones.
False (B)
Acamprosate primarily influences alcohol abstinence by directly inhibiting the NMDA receptor.
Acamprosate primarily influences alcohol abstinence by directly inhibiting the NMDA receptor.
False (B)
Minnesota model inpatient treatments have been shown to be more cost-effective than standard outpatient treatments for alcohol use disorders.
Minnesota model inpatient treatments have been shown to be more cost-effective than standard outpatient treatments for alcohol use disorders.
Disulfiram's effectiveness in treating alcohol use disorder is heightened when patients are unaware they are taking the medication.
Disulfiram's effectiveness in treating alcohol use disorder is heightened when patients are unaware they are taking the medication.
In treating alcohol use disorder, motivational interviewing avoids any direct advice or guidance to encourage behavior change.
In treating alcohol use disorder, motivational interviewing avoids any direct advice or guidance to encourage behavior change.
According to DSM-5, the diagnostic category previously known as 'alcohol abuse' remains separate and distinct from 'alcohol dependence.'
According to DSM-5, the diagnostic category previously known as 'alcohol abuse' remains separate and distinct from 'alcohol dependence.'
Nalmefene is indicated for alcohol dependence treatment and functions as selective opioid receptor antagonist to reduce alcohol reward.
Nalmefene is indicated for alcohol dependence treatment and functions as selective opioid receptor antagonist to reduce alcohol reward.
Psychological treatments primarily address the physiological cravings, whereas pharmacological treatments focus on increasing patient motivation in alcohol use disorder.
Psychological treatments primarily address the physiological cravings, whereas pharmacological treatments focus on increasing patient motivation in alcohol use disorder.
Topiramate's clinical effectiveness in reducing heavy drinking events is completely independent of any pre-existing genetic variations.
Topiramate's clinical effectiveness in reducing heavy drinking events is completely independent of any pre-existing genetic variations.
Flashcards
Nalmefene
Nalmefene
Used 'as needed' for heavy drinking patients, reduces (heavy) alcohol use.
Treatment Strategies
Treatment Strategies
Helps with treatment compliance, combines psychotherapy, pharmacotherapy and personalized medicine.
Topiramate
Topiramate
An atypical anti-epileptic drug that blocks voltage-gated sodium channels and high-voltage-activated calcium channels.
Alcohol Use Treatment
Alcohol Use Treatment
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Precontemplation Stage
Precontemplation Stage
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Motivational Interviewing
Motivational Interviewing
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Motivational Enhancement Therapy
Motivational Enhancement Therapy
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Standard AUD Treatments
Standard AUD Treatments
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Disulfiram
Disulfiram
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Naltrexone
Naltrexone
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Study Notes
Time-varying Fields and Maxwell's Equations
- Maxwell's Equations comprise a set of equations explaining all classical electromagnetism (EM) phenomena.
- Displacement current is Maxwell's prediction of a magnetic field being produced by a time-varying electric field.
- The displacement current density is expressed as $\vec{J}_d = \varepsilon_0 \frac{\partial \vec{E}}{\partial t}$.
- Generalized Ampere's Law, incorporating displacement current, is also known as Ampere-Maxwell's Law: $\nabla \times \vec{B} = \mu_0 \vec{J} + \mu_0 \varepsilon_0 \frac{\partial \vec{E}}{\partial t}$.
- The integral form of Ampere-Maxwell's Law is $\oint \vec{B} \cdot d\vec{l} = \mu_0 I + \mu_0 \varepsilon_0 \frac{d\Phi_E}{dt}$, where $\Phi_E = \int \vec{E} \cdot d\vec{A}$.
Application of Ampere's Law
- While charging a cylindrical capacitor, Ampere's Law can be applied to find the magnetic field between the plates.
- Along an Amperian loop, $\oint \vec{B} \cdot d\vec{l} = B(2\pi r) = \mu_0 I_{enc}$.
- For $r > R$, the magnetic field is $B = \frac{\mu_0 I}{2\pi r}$.
Free Space
- In free space, Maxwell's Equations are:
- $\nabla \cdot \vec{E} = 0$.
- $\nabla \cdot \vec{B} = 0$.
- $\nabla \times \vec{E} = -\frac{\partial \vec{B}}{\partial t}$.
- $\nabla \times \vec{B} = \mu_0 \varepsilon_0 \frac{\partial \vec{E}}{\partial t}$.
- These equations predict the existence of electromagnetic (EM) waves.
- EM waves propagate in free space at a speed of $c = \frac{1}{\sqrt{\mu_0 \varepsilon_0}} = 3.0 \times 10^8 \text{ m/s}$.
- Light is an electromagnetic wave.
Properties of Plane Electromagnetic Waves
- Electric and magnetic fields are perpendicular.
- Wave propagation occurs in the direction given by $\vec{E} \times \vec{B}$.
- Fields have the relationship $E = cB$.
- Polarization of an EM wave is defined by the direction of the $\vec{E}$ field.
Energy and Momentum of EM Waves
- Energy flow per unit area is described by the Poynting vector $\vec{S}$, given by $\vec{S} = \frac{1}{\mu_0} \vec{E} \times \vec{B}$.
- The direction of $\vec{S}$ indicates the direction of the wave propagation, and the magnitude is the power per unit area.
- Intensity is the time-averaged value of the Poynting vector: $I = \langle S \rangle = \frac{E_0 B_0}{2\mu_0} = \frac{E_0^2}{2\mu_0 c} = \frac{c B_0^2}{2\mu_0}$.
- EM waves exert radiation pressure on surfaces.
- If completely absorbed, the radiation pressure is $P = \frac{I}{c}$.
- If completely reflected, the radiation pressure is $P = \frac{2I}{c}$.
Channel Capacity
Channel Capacity Definition
- Channel capacity of a communication channel represents the maximum rate of information that can be reliably transmitted.
- Reliable communication means the probability of error can be made arbitrarily small.
Discrete Memoryless Channel (DMC) Definition:
- Input alphabet: $\mathcal{X}$
- Output alphabet: $\mathcal{Y}$
- Transition probabilities: $p(y|x)$, $x \in \mathcal{X}$, $y \in \mathcal{Y}$
- Channel Capacity: $C = \max_{p(x)} I(X;Y)$ in bits per channel use.
- $I(X;Y)$ is the mutual information between the input $X$ and the output $Y$, with the maximum taken over all possible input distributions $p(x)$.
Examples of Channel Capacity Calculations
-
Noiseless Binary Channel:
- Transmission: $X \rightarrow Y$, with $Y = X$
- Channel Matrix: $$ P = \begin{bmatrix} 1 & 0 \ 0 & 1 \end{bmatrix} $$
- Channel Capacity: $C = 1$ bit
- Achieved by using the channel once per bit.
-
Noisy Channel with Non-Overlapping Outputs:
- Transmission: Each input leads to a unique output.
- Channel Capacity: $C = \log |\mathcal{X}|$
- $|\mathcal{X}|$ is the size of the input alphabet.
-
Noisy Typewriter:
- Input: English text (26 letters)
- Output: if $X = a$ then Y = $a$ or Y = $b$ with equal probability
- Channel Capacity: $C = \log 13$
-
Binary Symmetric Channel (BSC):
- Transition Probabilities: $$ P(Y=0|X=0) = P(Y=1|X=1) = 1-p $$ $$ P(Y=0|X=1) = P(Y=1|X=0) = p $$ where $0 \le p \le 1$.
- Channel Capacity: $C = 1 - H(p)$ bits
- $H(p) = -p \log p - (1-p) \log (1-p)$ is the binary entropy function.
-
Binary Erasure Channel (BEC):
- Input Alphabet: $\mathcal{X} = {0, 1}$
- Output Alphabet: $\mathcal{Y} = {0, 1, e}$ ('e' denotes erasure)
- Transition Probabilities: $P(Y=0|X=0) = 1 - \alpha$, $P(Y=e|X=0) = \alpha$ $P(Y=1|X=1) = 1 - \alpha$, $P(Y=e|X=1) = \alpha$
- Channel Capacity: $C = 1 - \alpha$ bits
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