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Questions and Answers
What is the primary function of the embryo's signal to the mother during maternal recognition of pregnancy?
What is the primary function of the embryo's signal to the mother during maternal recognition of pregnancy?
- To stimulate the production of hormones that support pregnancy. (correct)
- To inform the mother's immune system to tolerate the embryo.
- To trigger implantation of the embryo in the uterine wall.
- To initiate the development of the placenta.
Which of the following is NOT a typical signal used by the embryo to indicate its presence to the mother?
Which of the following is NOT a typical signal used by the embryo to indicate its presence to the mother?
- Release of prostaglandins.
- Suppression of the mother's immune response.
- Production of progesterone. (correct)
- Secretion of human chorionic gonadotropin (hCG).
What is the main purpose of the embryo suppressing the mother's immune response during the early stages of pregnancy?
What is the main purpose of the embryo suppressing the mother's immune response during the early stages of pregnancy?
- To prevent the embryo from being recognized as foreign tissue. (correct)
- To increase the efficiency of nutrient transport across the placenta.
- To reduce the chances of the mother developing an autoimmune disease.
- To facilitate the development of the fetus's immune system.
Why is maternal recognition of pregnancy crucial for the continuation of a successful pregnancy?
Why is maternal recognition of pregnancy crucial for the continuation of a successful pregnancy?
What would be the likely outcome if the embryo failed to signal its presence to the mother?
What would be the likely outcome if the embryo failed to signal its presence to the mother?
In which placental classification is the chorionic epithelium in contact with the uterine epithelium?
In which placental classification is the chorionic epithelium in contact with the uterine epithelium?
Which type of placenta is considered the most efficient in nutrient transfer to the fetus?
Which type of placenta is considered the most efficient in nutrient transfer to the fetus?
What is the primary function of the pigment zona in the zonary placenta?
What is the primary function of the pigment zona in the zonary placenta?
In which type of placenta does erosion of the uterine connective tissue occur, resulting in the chorion being in direct contact with maternal capillaries?
In which type of placenta does erosion of the uterine connective tissue occur, resulting in the chorion being in direct contact with maternal capillaries?
Which of the following is NOT a characteristic of the discoid placenta?
Which of the following is NOT a characteristic of the discoid placenta?
The process by which placental cells interact with the spiral arteries to enhance metabolic exchange is known as:
The process by which placental cells interact with the spiral arteries to enhance metabolic exchange is known as:
Which of the following is a condition that can arise when placental access to maternal blood is limited?
Which of the following is a condition that can arise when placental access to maternal blood is limited?
The placental barrier is best described as:
The placental barrier is best described as:
What is the primary mechanism by which gases and water move across the placental barrier?
What is the primary mechanism by which gases and water move across the placental barrier?
Which of the following is a TRUE statement regarding the placental classification system?
Which of the following is a TRUE statement regarding the placental classification system?
Which of the following is NOT a function of the placenta?
Which of the following is NOT a function of the placenta?
Which extraembryonic membrane is derived from the trophoblast and mesoderm?
Which extraembryonic membrane is derived from the trophoblast and mesoderm?
The maternal recognition of pregnancy must occur prior to what physiological process?
The maternal recognition of pregnancy must occur prior to what physiological process?
Where does the conceptus spend a lengthy period during its migration within the uterus?
Where does the conceptus spend a lengthy period during its migration within the uterus?
What is the primary function of the amnion?
What is the primary function of the amnion?
Which type of placenta is characterized by multiple, discrete areas of attachment between the chorion and endometrium?
Which type of placenta is characterized by multiple, discrete areas of attachment between the chorion and endometrium?
Which of the following is NOT a common medical reason for amniocentesis?
Which of the following is NOT a common medical reason for amniocentesis?
What hormone is responsible for maintaining a calm uterine environment, allowing for embryo implantation?
What hormone is responsible for maintaining a calm uterine environment, allowing for embryo implantation?
Which type of placenta is seen in horses and pigs?
Which type of placenta is seen in horses and pigs?
Which extraembryonic membrane is the primary site of early blood cell formation?
Which extraembryonic membrane is the primary site of early blood cell formation?
What is the function of the chorion?
What is the function of the chorion?
The presence of which protein in amniotic fluid can indicate neural tube defects?
The presence of which protein in amniotic fluid can indicate neural tube defects?
Which extraembryonic membrane is essential for the formation of the umbilical cord in mammals?
Which extraembryonic membrane is essential for the formation of the umbilical cord in mammals?
What is the correct order of fetal membrane layers from innermost to outermost?
What is the correct order of fetal membrane layers from innermost to outermost?
What is the name of the structure formed by the interaction of a cotyledon and a caruncle?
What is the name of the structure formed by the interaction of a cotyledon and a caruncle?
What is the primary function of the placenta during pregnancy?
What is the primary function of the placenta during pregnancy?
Which process allows trophoblastic cells to encapsulate maternal plasma and transport it into fetal circulation?
Which process allows trophoblastic cells to encapsulate maternal plasma and transport it into fetal circulation?
What condition occurs when the placenta implants too low in the uterus, potentially obstructing delivery?
What condition occurs when the placenta implants too low in the uterus, potentially obstructing delivery?
Which grade of placenta accreta involves chorionic villi invading into the myometrium?
Which grade of placenta accreta involves chorionic villi invading into the myometrium?
What serious condition involves the premature separation of the placenta from the uterus?
What serious condition involves the premature separation of the placenta from the uterus?
Which of the following substances can cross the placenta through active transport?
Which of the following substances can cross the placenta through active transport?
Which placental abnormality is characterized by the chorionic villi invading through the serosa?
Which placental abnormality is characterized by the chorionic villi invading through the serosa?
What type of transport mechanism is primarily used for the active transport of ions like calcium across the placenta?
What type of transport mechanism is primarily used for the active transport of ions like calcium across the placenta?
What is a potential consequence of placenta previa during pregnancy?
What is a potential consequence of placenta previa during pregnancy?
How does the placenta act as an endocrine organ?
How does the placenta act as an endocrine organ?
Flashcards
Maternal Recognition of Pregnancy
Maternal Recognition of Pregnancy
The process by which an embryo signals its mother to modify her body in preparation for pregnancy.
Embryonic Signaling
Embryonic Signaling
The biochemical signals released by the embryo to communicate its presence to the mother.
Hormonal Changes
Hormonal Changes
Changes in hormone levels triggered by the embryo's signals that help sustain pregnancy.
Implantation
Implantation
The process of the embryo attaching itself to the uterine wall after maternal recognition.
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Pregnancy Maintenance
Pregnancy Maintenance
The physiological adaptations that occur in the mother to support the developing embryo throughout gestation.
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Active Transport in Placenta
Active Transport in Placenta
Mechanism using pumps to move sodium, potassium, and calcium across the placenta.
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Pinocytosis
Pinocytosis
Process where trophoblastic cells engulf maternal plasma and solutes in vacuoles.
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Placenta as Endocrine Organ
Placenta as Endocrine Organ
The placenta produces hormones that regulate pregnancy and fetal development.
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Placenta Previa
Placenta Previa
Condition where the placenta obstructs the cervical canal, potentially blocking delivery.
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Placenta Accreta
Placenta Accreta
Abnormal placenta attachment with chorionic villi invading the myometrium.
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Grades of Placenta Accreta
Grades of Placenta Accreta
Three grades based on the level of invasion by chorionic villi into myometrium.
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Placenta Abruption
Placenta Abruption
Separation of the placenta from the uterus prematurely, often leading to complications.
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Functions of the Placenta
Functions of the Placenta
Exchange of nutrients, production of hormones, and protection of the fetus.
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Placental Classifications
Placental Classifications
Placentas are classified by shape and type of barrier between blood supplies.
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Placental Abnormalities
Placental Abnormalities
Conditions like previa, accreta, and abruption that disrupt safe birth.
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Conceptus signaling
Conceptus signaling
The biochemical signals that the conceptus sends to the mother to indicate its presence and maintain pregnancy.
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Role of Progesterone
Role of Progesterone
Hormone that keeps the uterus calm, allowing the embryo to implant properly.
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Gestation Day 14
Gestation Day 14
The last day of the uterine migration phenomenon of a conceptus during early pregnancy.
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Extraembryonic membranes
Extraembryonic membranes
Membranes developed to support the fetus by providing nutrients, oxygen, and protection against the mother's immune system.
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Amnion
Amnion
The innermost fetal membrane enclosing the embryo, providing protection and accommodating growth.
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Yolk Sac
Yolk Sac
An extraembryonic membrane that serves as the early site for blood formation and connects to the embryo's midgut.
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Amniocentesis
Amniocentesis
Medical procedure used to collect amniotic fluid and cells for detecting genetic diseases and conditions during pregnancy.
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Allantois
Allantois
Innermost layer of fetal membranes involved in the formation of the umbilical cord and waste collection.
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Chorion
Chorion
The outermost layer of fetal membranes, which develops into the placenta.
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Placenta
Placenta
An organ connecting the fetus to the mother's uterine wall for nutrient and waste exchange.
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Diffuse placenta
Diffuse placenta
Type of placenta where almost the entire surface of the chorion contributes to placenta formation, seen in horses and pigs.
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Cotyledonary placenta
Cotyledonary placenta
Type of placenta with multiple discrete attachment areas (cotyledons) interacting with the uterus, found in cows and sheep.
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Zonary placenta
Zonary placenta
Placenta forms a band of tissue surrounding the fetus, complete or incomplete.
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Placenta functions
Placenta functions
Supports pregnancy through nutrient uptake, gas exchange, and waste elimination for the fetus.
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Discoid Placenta
Discoid Placenta
A placenta shaped like a disc, forming a single patch for nutrient exchange, common in humans.
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Pre-eclampsia
Pre-eclampsia
A pregnancy complication with high blood pressure due to limited placental access.
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Epitheliochorial
Epitheliochorial
The least invasive placenta type where chorion contacts uterine epithelium without maternal tissue loss.
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Syndesmochorial
Syndesmochorial
A placenta type where uterine epithelium is locally eroded, allowing chorion to enter connective tissue.
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Endotheliochorial
Endotheliochorial
A placenta type where chorion contacts maternal capillaries after eroding connective tissue.
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Hemochorial
Hemochorial
The most invasive placenta type, with chorionic villi in direct contact with maternal blood.
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Placental Barrier
Placental Barrier
A semi-permeable layer in the placenta that selectively allows substances to pass between maternal and fetal blood.
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Simple Diffusion
Simple Diffusion
The process where substances move from high to low concentration without energy.
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Facilitated Diffusion
Facilitated Diffusion
An enhanced rate of substance movement across a membrane, requiring specific proteins.
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Maternal Recognition of Pregnancy
- The conceptus signals its presence to the mother through a critical series of events.
- Timely biochemical signals from the conceptus are essential for successful pregnancy; otherwise, pregnancy terminates.
- Maternal recognition must occur before luteolysis (end of the corpus luteum function).
- Estrogen can cause uterine contractions, hindering embryo implantation.
- Progesterone maintains a calm uterine environment conducive to embryo implantation.
- The conceptus migrates within the uterus, with specific stopping points.
Fetal Membranes
- Extraembryonic membranes develop to protect and nourish the fetus.
- The fetus's different genetic makeup necessitates protection from the mother's immune system.
- The mother supplies nutrients, oxygen, and protection, while removing waste produced by the fetus.
Amnion
- Formed from extraembryonic ectoderm and somatic mesoderm.
- Suspends and protects the fetus from injury, accommodating growth and movement.
Yolk Sac
- Derived from extraembryonic endoderm.
- An early site of blood formation, connected to the embryo's midgut by the yolk stalk.
Amniocentesis
- A medical procedure, performed if there are medical concerns, particularly regarding fetal chromosomal abnormalities.
- Amniotic fluid and/or cells are collected and examined to detect diseases like Tay-Sachs, sex determination, or trisomy.
- Proteins in the fluid can signal neural tube defects.
- Cells can reveal genetic defects.
Allantois
- Formed from the trophoblast and mesoderm.
- Crucial in mammalian umbilical cord formation.
- Collects waste products from the fetus.
Chorion
- The outermost fetal membrane, surrounding the amnion.
- Develops villi, forming the placenta.
Placenta
- An organ connecting the fetus to the uterine wall.
- Enables metabolic exchange (nutrients, gases, thermoregulation, infection defense, waste elimination).
- Produces pregnancy-supporting hormones.
- Composed of fetal (chorion) and maternal (uterine endometrium) components.
- Different types of placentation exist, differing in shape and tissue interaction.
Placental Classifications
- Diffuse Placenta: Chorion's entire surface is involved. (Horse, Pig)
- Cotyledonary Placenta: Discrete attachment sites (cotyledons) interact with maternal tissues. (Cow, Sheep)
- Zonary Placenta: Placenta forms a band surrounding the fetus. (Dog, Cat, Seals, Elephants)
- Discoid Placenta: Single, disc-shaped placenta. (Human, Primates, Rodents)
Mechanisms of Transport Across the Placenta
- Simple Diffusion: Movement of gases and water due to concentration gradients.
- Facilitated Diffusion: Faster than simple diffusion; involves sugars, amino acids, and salts.
- Active Transport: Placenta actively pumps sodium, potassium, and calcium.
- Pinocytosis: Cells engulf maternal plasma and release contents into fetal circulation, facilitating transfer of various molecules.
Placenta as Endocrine Organ
- The placenta produces hormones crucial for supporting pregnancy.
Multiple Pregnancies
- Placental structure may vary in multiple pregnancies.
Placental Abnormalities
- Placenta Previa: Placenta implants too low, potentially obstructing delivery.
- Placenta Accreta: Abnormal placental attachment to the uterine wall.
- Placenta Abruption: Separation of the placenta from the uterus before birth.
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