Maternal-Fetal Unit: Hormonal Changes During Pregnancy

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Which hormone is primarily responsible for preventing premature uterine contractions and expulsion of the fetus during pregnancy?

Progesterone

What is the primary source of estrogen and progesterone during the first two months of pregnancy?

The corpus luteum

Which hormone secreted by the trophoblast cells is responsible for maintaining the corpus luteum and its steroid production during early pregnancy?

Human chorionic gonadotropin (hCG)

What is the primary function of estrogen during pregnancy?

Stimulating uterine muscle growth

Which hormone is primarily responsible for initiating parturition (labor and delivery)?

Prostaglandin F2α

What is the proposed mechanism behind the "placental clock" theory of parturition initiation?

Increased production of prostaglandins by the placenta

Which hormone is primarily responsible for stimulating fetal adrenal steroid production, leading to increased estrogen and prostaglandin levels that contribute to parturition?

Adrenocorticotropic hormone (ACTH)

What is the primary function of prostaglandins in the initiation of parturition?

Stimulating uterine contractions

Which of the following statements regarding the role of the fetal adrenal glands in parturition is correct?

Fetal adrenal steroid production stimulates placental estrogen synthesis

What is the proposed mechanism behind the "fetal cortisol surge" theory of parturition initiation?

Increased fetal cortisol production stimulates placental prostaglandin synthesis

Learn about the crucial role of maternal nutrition and the hormonal changes that occur during pregnancy. Understand how estrogen and progesterone affect the uterine muscle mass and contractility to support fetal development.

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