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Questions and Answers
Which of the following is a common adverse effect of trimethoprim-sulfamethoxazole (TMP-SMX)?
Which of the following is a common adverse effect of trimethoprim-sulfamethoxazole (TMP-SMX)?
- Acute kidney injury (correct)
- Hypertension
- Elevated blood glucose levels
- Joint pain
What is the mechanism of action of TMP-SMX?
What is the mechanism of action of TMP-SMX?
- Inhibition of bacterial folic acid synthesis (correct)
- Inhibition of bacterial DNA replication
- Inhibition of bacterial cell wall synthesis
- Inhibition of bacterial protein synthesis
Which of the following adverse effects of TMP-SMX is more common in immunocompromised individuals, such as those with HIV?
Which of the following adverse effects of TMP-SMX is more common in immunocompromised individuals, such as those with HIV?
- Rash and pruritis
- Stevens-Johnson syndrome (correct)
- Gastrointestinal disturbances
- Phototoxicity
What can occur if TMP-SMX is used concomitantly with potassium-sparing diuretics?
What can occur if TMP-SMX is used concomitantly with potassium-sparing diuretics?
Which of the following is a potential drug interaction with TMP-SMX that may increase INR levels?
Which of the following is a potential drug interaction with TMP-SMX that may increase INR levels?
What is the recommended approach to minimize gastrointestinal disturbances associated with TMP-SMX?
What is the recommended approach to minimize gastrointestinal disturbances associated with TMP-SMX?
What adverse effect of TMP-SMX is characterized by rash and pruritis that typically occurs 7-14 days after treatment?
What adverse effect of TMP-SMX is characterized by rash and pruritis that typically occurs 7-14 days after treatment?
What is the spectrum of activity of TMP-SMX?
What is the spectrum of activity of TMP-SMX?
What adverse effect of TMP-SMX is characterized by anemia due to folate deficiency?
What adverse effect of TMP-SMX is characterized by anemia due to folate deficiency?
What adverse effect of TMP-SMX is characterized by issues with multiple blood lines and can occur with higher doses and chronic use?
What adverse effect of TMP-SMX is characterized by issues with multiple blood lines and can occur with higher doses and chronic use?
Which of the following is the mechanism of action of Daptomycin?
Which of the following is the mechanism of action of Daptomycin?
What is the dosing of Daptomycin for severe skin soft tissue infections?
What is the dosing of Daptomycin for severe skin soft tissue infections?
Which of the following is NOT a severe adverse effect of Daptomycin?
Which of the following is NOT a severe adverse effect of Daptomycin?
What is the primary route of excretion for Daptomycin?
What is the primary route of excretion for Daptomycin?
What is the spectrum of activity of Daptomycin?
What is the spectrum of activity of Daptomycin?
What is the mechanism of action of Colistimethate sodium?
What is the mechanism of action of Colistimethate sodium?
Which of the following is NOT a use of Colistin?
Which of the following is NOT a use of Colistin?
What adverse effect is commonly associated with Colistin use?
What adverse effect is commonly associated with Colistin use?
What is the protein binding of Colistimethate?
What is the protein binding of Colistimethate?
Which of the following is a drug-drug interaction with Colistin?
Which of the following is a drug-drug interaction with Colistin?
Which of the following is a potential adverse effect of tetracyclines?
Which of the following is a potential adverse effect of tetracyclines?
What is the primary route of excretion for tigecycline?
What is the primary route of excretion for tigecycline?
Which of the following is NOT a use of tigecycline?
Which of the following is NOT a use of tigecycline?
What is the mechanism of action of tetracyclines?
What is the mechanism of action of tetracyclines?
Which of the following is a potential drug interaction with tetracyclines?
Which of the following is a potential drug interaction with tetracyclines?
Which of the following tetracyclines has the longest half-life?
Which of the following tetracyclines has the longest half-life?
Which tetracycline is 2- to 4-fold more active against Gram-positive cocci compared to tigecycline?
Which tetracycline is 2- to 4-fold more active against Gram-positive cocci compared to tigecycline?
Which tetracycline is aminomethylcycline, a minocycline derivative?
Which tetracycline is aminomethylcycline, a minocycline derivative?
Which tetracycline has a bioavailability of 35% and should be taken with plenty of water on an empty stomach?
Which tetracycline has a bioavailability of 35% and should be taken with plenty of water on an empty stomach?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which of the following is the mechanism of action of Tetracyclines?
Which of the following is the mechanism of action of Tetracyclines?
Which of the following is the spectrum of activity of Tetracyclines?
Which of the following is the spectrum of activity of Tetracyclines?
Which of the following is an adverse effect of Tetracyclines?
Which of the following is an adverse effect of Tetracyclines?
Which of the following is the recommended dosing of Doxycycline for Chlamydia trachomatis?
Which of the following is the recommended dosing of Doxycycline for Chlamydia trachomatis?
Which of the following is an adverse effect of Minocycline?
Which of the following is an adverse effect of Minocycline?
Which of the following is the spectrum of activity of Daptomycin?
Which of the following is the spectrum of activity of Daptomycin?
What is the recommended dosing of Doxycycline for Chlamydia trachomatis?
What is the recommended dosing of Doxycycline for Chlamydia trachomatis?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which of the following is an adverse effect of Minocycline?
Which of the following is an adverse effect of Minocycline?
What is the primary route of excretion for tigecycline?
What is the primary route of excretion for tigecycline?
Which of the following statements about tetracyclines is correct?
Which of the following statements about tetracyclines is correct?
What is the mechanism of action of tigecycline?
What is the mechanism of action of tigecycline?
Which of the following is NOT a recommended use of tigecycline?
Which of the following is NOT a recommended use of tigecycline?
What is the primary route of excretion for daptomycin?
What is the primary route of excretion for daptomycin?
Which of the following adverse effects is NOT associated with daptomycin use?
Which of the following adverse effects is NOT associated with daptomycin use?
Which tetracycline has the longest half-life?
Which tetracycline has the longest half-life?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which tetracycline should be administered at least 1 to 2 hours prior to, or 4 hours after antacids and supplements to avoid chelation and reduce its total absorption?
Which tetracycline is aminomethylcycline, a minocycline derivative?
Which tetracycline is aminomethylcycline, a minocycline derivative?
Which tetracycline is 2- to 4-fold more active against Gram-positive cocci compared to tigecycline?
Which tetracycline is 2- to 4-fold more active against Gram-positive cocci compared to tigecycline?
Which tetracycline has a bioavailability of 35% and should be taken with plenty of water on an empty stomach?
Which tetracycline has a bioavailability of 35% and should be taken with plenty of water on an empty stomach?
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