Mastering the Basics of Thyroid Stimulating Hormone (TSH)
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Questions and Answers

What is the role of thyrotrophin releasing factor (TRF) in the synthesis and release of thyroid stimulating hormone (TSH)?

Thyrotrophin releasing factor (TRF) from the hypothalamus stimulates the synthesis and release of thyroid stimulating hormone (TSH) from the anterior pituitary.

How does TSH regulate the endocrine function of the thyroid gland?

TSH increases the number of cells and secretory activity of the thyroid gland, regulating its endocrine function.

What are the consequences of over secretion and under secretion of TSH?

Over secretion of TSH causes hyperthyroidism (excess of thyroxin), while under secretion of TSH causes hypothyroidism (lack of thyroxin).

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