Chapter 46 and 47
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Questions and Answers

Which of the following is the chief inhibitory transmitter in the adult CNS?

  • GABA (correct)
  • ENa
  • Glutamate
  • EK
  • What is the main body of a neuron called?

  • Axon terminal
  • Dendrite
  • Soma (correct)
  • Synaptic
  • Which of the following is an electrotonic response that decays with an exponential time course?

  • Threshold potential
  • Action potential
  • IPSP
  • EPSP (correct)
  • What type of summation occurs when EPSPs created by distant synapses overlap?

    <p>Spatial summation</p> Signup and view all the answers

    What is the neurotransmitter that opens cation channels and is the chief excitatory transmitter in the CNS?

    <p>Glutamate</p> Signup and view all the answers

    What is the term for the increased transmitter release produced by an action potential that follows closely upon a preceding action potential?

    <p>Facilitation</p> Signup and view all the answers

    Which lobe of the cerebral cortex is responsible for auditory perception, semantics, and memory?

    <p>Temporal lobe</p> Signup and view all the answers

    Which lobe of the cerebral cortex is the visual processing center?

    <p>Occipital lobe</p> Signup and view all the answers

    Which level of the central nervous system contains the medulla, pons, mesencephalon, hypothalamus, thalamus, cerebellum, and basal ganglia?

    <p>Lower brain level</p> Signup and view all the answers

    Which portion of the nervous system is responsible for tactile, visual, auditory, and olfactory sensations?

    <p>Sensory Division</p> Signup and view all the answers

    Which level of the central nervous system contains walking circuits, withdrawal circuits, and support against gravity circuits?

    <p>Spinal cord level</p> Signup and view all the answers

    Which level of the central nervous system is essential for thought processes and functions in association with lower centers?

    <p>Higher brain or cortical level</p> Signup and view all the answers

    Which type of neurotransmitter is usually inhibitory in the central nervous system (CNS)?

    <p>Glycine</p> Signup and view all the answers

    What is the main function of small molecule, rapidly acting transmitters in the nervous system?

    <p>Mediate most acute responses</p> Signup and view all the answers

    What is the role of neuropeptides in synaptic transmission?

    <p>Cause long-term changes</p> Signup and view all the answers

    What is the mechanism by which mechanical deformation generates a receptor potential?

    <p>Depolarization</p> Signup and view all the answers

    What is the term for the principle that each receptor responds to a limited range of stimuli and has a direct line to the brain?

    <p>Labeled-line principle</p> Signup and view all the answers

    What environmental change increases neuronal excitability and can initiate petit mal seizures?

    <p>Alkalosis</p> Signup and view all the answers

    Which of the following is true about abnormal ion concentration in axon D?

    <p>It leads to downregulation of membrane receptors</p> Signup and view all the answers

    What happens when there is underactivity in synaptic sensitivity?

    <p>It leads to upregulation of membrane receptors</p> Signup and view all the answers

    What happens when there is overactivity in synaptic sensitivity?

    <p>It leads to downregulation of membrane receptors</p> Signup and view all the answers

    What is the characteristic of reverberatory circuits?

    <p>They show continuous output</p> Signup and view all the answers

    What type of information transmission does the ANS use to control vascular tone, gut tone, heart rate, etc.?

    <p>Continuous output from reverberating circuit</p> Signup and view all the answers

    What is shown in Figure 47-16?

    <p>Control of synaptic sensitivity</p> Signup and view all the answers

    Which type of receptor responds only when a change in stimulus is taking place?

    <p>Rapidly adapting receptors</p> Signup and view all the answers

    What is the mechanism of adaptation in mechanoreceptors like the Pacinian corpuscle?

    <p>Fluid redistribution decreases distorting force</p> Signup and view all the answers

    Which type of receptor continues to transmit impulses to the brain for long periods of time while the stimulus is present?

    <p>Slowly adapting receptors</p> Signup and view all the answers

    What is the importance of signal intensity in the interpretation of signals by the brain?

    <p>Gradations in signal intensity can be achieved by spatial and temporal summation</p> Signup and view all the answers

    Which type of neuronal circuit comprises many different types of neuronal circuits and includes converging, diverging, reverberating, and inhibitory circuits?

    <p>Reverberatory or oscillatory circuits</p> Signup and view all the answers

    What is the mechanism that causes the prolonged output in a reverberatory circuit after a single input stimulus?

    <p>Positive feedback within the neuronal circuit</p> Signup and view all the answers

    Study Notes

    Neuron Structure and Function

    • Chief inhibitory transmitter in the adult CNS is GABA (Gamma-Aminobutyric Acid).
    • Main body of a neuron is called the soma or cell body.
    • Electrotonic response that decays with an exponential time course is known as a graded potential.
    • EPSPs (Excitatory Postsynaptic Potentials) from distant synapses that overlap exhibit spatial summation.

    Neurotransmitters

    • Chief excitatory transmitter in the CNS that opens cation channels is glutamate.
    • Increased transmitter release following closely upon a preceding action potential is termed facilitation.
    • Small molecule, rapidly acting transmitters function primarily in fast synaptic transmission.
    • Neuropeptides play a role in modulating synaptic transmission and can influence the strength of synaptic responses.

    Cerebral Cortex and CNS Levels

    • Temporal lobe is responsible for auditory perception, semantics, and memory.
    • Occipital lobe is the primary visual processing center.
    • Forebrain and hindbrain levels of the central nervous system include the medulla, pons, mesencephalon, hypothalamus, thalamus, cerebellum, and basal ganglia.
    • The upper levels of the central nervous system are essential for higher thought processes and associations with lower centers.

    Sensory Functions and Receptor Mechanisms

    • The sensory system encompasses tactile, visual, auditory, and olfactory sensations.
    • Mechanoreceptors convert mechanical deformation into receptor potentials through mechanotransduction.
    • The principle of labeled line coding describes the specific pathway each receptor uses to communicate specific types of stimuli to the brain.
    • Changes in environmental conditions, such as hypercapnia (increased CO2), can elevate neuronal excitability, potentially causing petit mal seizures.

    Synaptic Sensitivity

    • Underactivity in synaptic sensitivity may lead to diminished responses to stimuli.
    • Overactivity in synaptic sensitivity can result in hyperexcitability or seizures.
    • Reverberatory circuits are characterized by prolonged activity due to feedback loops that sustain output after a single input.

    Information Transmission in the Nervous System

    • The Autonomic Nervous System (ANS) utilizes hormonal and neurotransmitter signals to regulate vascular and gut tones and heart rate.
    • Receptors that respond only during changing stimulus conditions are known as phasic receptors.
    • Adaptation in mechanoreceptors, such as the Pacinian corpuscle, occurs via rapid adaptation to sustained stimuli.
    • Tonic receptors consistently transmit signals to the brain as long as the stimulus is present, providing continuous feedback.

    Signal Interpretation

    • Signal intensity plays a crucial role in how the brain interprets sensory information, encoding the strength of stimuli.
    • Neuronal circuits might include various types, such as converging, diverging, reverberating, and inhibitory networks.
    • Prolonged output in reverberatory circuits after a single stimulus is caused by sustained positive feedback within the circuit.

    Summary

    • These concepts underline the complex interactions within the nervous system, highlighting synaptic processes, cortical functions, and sensory receptor mechanisms.

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    Test your knowledge on the special characteristics of synaptic transmission! Learn about synaptic facilitation, the role of calcium ions in presynaptic terminals, and the mechanism behind increased vesicular release of transmitter. Explore synaptic fatigue and short-term synaptic depression. Challenge yourself with questions on excitatory synapses and the effects of rapid stimulation.

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