Mastering Gluconeogenesis and Glycerol Release
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Questions and Answers

Which enzyme phosphorylates glycerol to glycerol phosphate?

  • Glycerol kinase (correct)
  • Glycerol synthase
  • Glycerol phosphatase
  • Glycerol dehydrogenase

    • What is the final product of gluconeogenesis?

  • Glucose (correct)
  • GTP
  • Pyruvate
  • NADH

    • What is the role of dihydroxyacetone phosphate in glycolysis?

  • It is a substrate for pyruvate kinase
  • It is a substrate for glyceraldehyde-3-phosphate dehydrogenase (correct)
  • It is a product of aldolase
  • It is a substrate for hexokinase

    • How many ATP molecules are used in gluconeogenesis?

    <p>4</p> Signup and view all the answers

    What is the fate of glycerol released during the hydrolysis of triacylglycerols in adipose tissue?

    <p>It is converted to glucose in the liver</p> Signup and view all the answers

    What is the role of NADH in gluconeogenesis?

    <p>It is oxidized to NAD+</p> Signup and view all the answers

    Which enzyme oxidizes glycerol phosphate to dihydroxyacetone phosphate?

    <p>Glycerol phosphate dehydrogenase</p> Signup and view all the answers

    What is the role of GTP in gluconeogenesis?

    <p>It is used to form glucose-6-phosphate</p> Signup and view all the answers

    What is the role of NAD+ in glycolysis?

    <p>It is a cofactor for glyceraldehyde-3-phosphate dehydrogenase</p> Signup and view all the answers

    What is the role of Pi in gluconeogenesis?

    <p>It is used to form glucose-6-phosphate</p> Signup and view all the answers

    Which enzyme phosphorylates glycerol to glycerol phosphate?

    <p>Glycerol kinase</p> Signup and view all the answers

    What is the final product of gluconeogenesis?

    <p>Glucose</p> Signup and view all the answers

    What is the role of dihydroxyacetone phosphate in glycolysis?

    <p>It is a substrate for glyceraldehyde-3-phosphate dehydrogenase</p> Signup and view all the answers

    How many ATP molecules are used in gluconeogenesis?

    <p>6</p> Signup and view all the answers

    What is the fate of glycerol released during the hydrolysis of triacylglycerols in adipose tissue?

    <p>It is converted to glucose in the liver</p> Signup and view all the answers

    What is the role of NADH in gluconeogenesis?

    <p>It is oxidized to NAD+</p> Signup and view all the answers

    Which enzyme oxidizes glycerol phosphate to dihydroxyacetone phosphate?

    <p>Glycerol phosphate dehydrogenase</p> Signup and view all the answers

    What is the role of GTP in gluconeogenesis?

    <p>It is used to form glucose-6-phosphate</p> Signup and view all the answers

    What is the role of NAD+ in glycolysis?

    <p>It is a cofactor for glyceraldehyde-3-phosphate dehydrogenase</p> Signup and view all the answers

    What is the role of Pi in gluconeogenesis?

    <p>It is used to form glucose-6-phosphate</p> Signup and view all the answers

    During gluconeogenesis, how many ~P bonds of ATP and GTP are used?

    <p>6</p> Signup and view all the answers

    What is the end product of gluconeogenesis?

    <p>glucose</p> Signup and view all the answers

    Where is glycerol released from during the hydrolysis of triacylglycerols?

    <p>adipose tissue</p> Signup and view all the answers

    What is glycerol kinase responsible for during the metabolism of glycerol?

    <p>phosphorylating glycerol</p> Signup and view all the answers

    What is the role of glycerol phosphate dehydrogenase during the metabolism of glycerol?

    <p>oxidizing glycerol phosphate</p> Signup and view all the answers

    What is the starting molecule for gluconeogenesis?

    <p>pyruvate</p> Signup and view all the answers

    What is the end product of the metabolism of glycerol?

    <p>dihydroxyacetone phosphate</p> Signup and view all the answers

    Where is glycerol phosphate dehydrogenase located?

    <p>liver tissue</p> Signup and view all the answers

    What is the role of NADH during gluconeogenesis?

    <p>to be oxidized to NAD+</p> Signup and view all the answers

    What is the role of GTP during gluconeogenesis?

    <p>to be oxidized to GDP</p> Signup and view all the answers

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