Mastering Gluconeogenesis and Glycerol Release

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Questions and Answers

Which enzyme phosphorylates glycerol to glycerol phosphate?

  • Glycerol kinase (correct)
  • Glycerol synthase
  • Glycerol phosphatase
  • Glycerol dehydrogenase

What is the final product of gluconeogenesis?

  • Glucose (correct)
  • GTP
  • Pyruvate
  • NADH

What is the role of dihydroxyacetone phosphate in glycolysis?

  • It is a substrate for pyruvate kinase
  • It is a substrate for glyceraldehyde-3-phosphate dehydrogenase (correct)
  • It is a product of aldolase
  • It is a substrate for hexokinase

How many ATP molecules are used in gluconeogenesis?

<p>4 (A)</p> Signup and view all the answers

What is the fate of glycerol released during the hydrolysis of triacylglycerols in adipose tissue?

<p>It is converted to glucose in the liver (D)</p> Signup and view all the answers

What is the role of NADH in gluconeogenesis?

<p>It is oxidized to NAD+ (A)</p> Signup and view all the answers

Which enzyme oxidizes glycerol phosphate to dihydroxyacetone phosphate?

<p>Glycerol phosphate dehydrogenase (C)</p> Signup and view all the answers

What is the role of GTP in gluconeogenesis?

<p>It is used to form glucose-6-phosphate (B)</p> Signup and view all the answers

What is the role of NAD+ in glycolysis?

<p>It is a cofactor for glyceraldehyde-3-phosphate dehydrogenase (D)</p> Signup and view all the answers

What is the role of Pi in gluconeogenesis?

<p>It is used to form glucose-6-phosphate (D)</p> Signup and view all the answers

Which enzyme phosphorylates glycerol to glycerol phosphate?

<p>Glycerol kinase (A)</p> Signup and view all the answers

What is the final product of gluconeogenesis?

<p>Glucose (A)</p> Signup and view all the answers

What is the role of dihydroxyacetone phosphate in glycolysis?

<p>It is a substrate for glyceraldehyde-3-phosphate dehydrogenase (A)</p> Signup and view all the answers

How many ATP molecules are used in gluconeogenesis?

<p>6 (A)</p> Signup and view all the answers

What is the fate of glycerol released during the hydrolysis of triacylglycerols in adipose tissue?

<p>It is converted to glucose in the liver (B)</p> Signup and view all the answers

What is the role of NADH in gluconeogenesis?

<p>It is oxidized to NAD+ (D)</p> Signup and view all the answers

Which enzyme oxidizes glycerol phosphate to dihydroxyacetone phosphate?

<p>Glycerol phosphate dehydrogenase (D)</p> Signup and view all the answers

What is the role of GTP in gluconeogenesis?

<p>It is used to form glucose-6-phosphate (C)</p> Signup and view all the answers

What is the role of NAD+ in glycolysis?

<p>It is a cofactor for glyceraldehyde-3-phosphate dehydrogenase (B)</p> Signup and view all the answers

What is the role of Pi in gluconeogenesis?

<p>It is used to form glucose-6-phosphate (B)</p> Signup and view all the answers

During gluconeogenesis, how many ~P bonds of ATP and GTP are used?

<p>6 (D)</p> Signup and view all the answers

What is the end product of gluconeogenesis?

<p>glucose (D)</p> Signup and view all the answers

Where is glycerol released from during the hydrolysis of triacylglycerols?

<p>adipose tissue (D)</p> Signup and view all the answers

What is glycerol kinase responsible for during the metabolism of glycerol?

<p>phosphorylating glycerol (C)</p> Signup and view all the answers

What is the role of glycerol phosphate dehydrogenase during the metabolism of glycerol?

<p>oxidizing glycerol phosphate (B)</p> Signup and view all the answers

What is the starting molecule for gluconeogenesis?

<p>pyruvate (B)</p> Signup and view all the answers

What is the end product of the metabolism of glycerol?

<p>dihydroxyacetone phosphate (A)</p> Signup and view all the answers

Where is glycerol phosphate dehydrogenase located?

<p>liver tissue (C)</p> Signup and view all the answers

What is the role of NADH during gluconeogenesis?

<p>to be oxidized to NAD+ (B)</p> Signup and view all the answers

What is the role of GTP during gluconeogenesis?

<p>to be oxidized to GDP (A)</p> Signup and view all the answers

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