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Mastering Anti-Mycobacterial Agents

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Questions and Answers

Which is the mechanism of action of Rifamycin?

Rifamycin enters the cell through the cell membrane

Rifamycin inhibits microbial DNA polymerase

Rifamycin inhibits microbial RNA polymerase (correct)

Rifamycin inhibits microbial protein synthesis

What is the spectrum of activity of Rifampin?

Fungi

Virus

Gram positive bacteria (correct)

Gram negative bacteria

What are the adverse effects of Rifampin?

Cardiotoxicity

Nephrotoxicity

Neurotoxicity

Hepatotoxicity (correct)

Which drug is known to cause orange discoloration of body fluids such as tears, sweat, saliva, urine, and feces?

Rifampin (A) Signup and view all the answers

What is the most common adverse effect of Isoniazid?

Hepatotoxicity (C) Signup and view all the answers

Which drug is associated with the adverse effect of optic neuritis?

Ethambutol (A) Signup and view all the answers

Which drug is a potent inducer of CYP P450 enzymes?