Mastering Anti-Mycobacterial Agents
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Questions and Answers

Which is the mechanism of action of Rifamycin?

  • Rifamycin enters the cell through the cell membrane
  • Rifamycin inhibits microbial DNA polymerase
  • Rifamycin inhibits microbial RNA polymerase (correct)
  • Rifamycin inhibits microbial protein synthesis

    • What is the spectrum of activity of Rifampin?

  • Fungi
  • Virus
  • Gram positive bacteria (correct)
  • Gram negative bacteria

    • What are the adverse effects of Rifampin?

  • Cardiotoxicity
  • Nephrotoxicity
  • Neurotoxicity
  • Hepatotoxicity (correct)

    • Which drug is known to cause orange discoloration of body fluids such as tears, sweat, saliva, urine, and feces?

    <p>Rifampin</p> Signup and view all the answers

    What is the most common adverse effect of Isoniazid?

    <p>Hepatotoxicity</p> Signup and view all the answers

    Which drug is associated with the adverse effect of optic neuritis?

    <p>Ethambutol</p> Signup and view all the answers

    Which drug is a potent inducer of CYP P450 enzymes?

    <p>Rifampin</p> Signup and view all the answers

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