Master the Intricacies of Perfusion

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Questions and Answers

Which of the following is NOT a step in the process of hemostasis?

  • Activation of plasma coagulation
  • Activation of platelets
  • Initiation of fibrinolysis (correct)
  • Release of inhibitors

Which of the following is responsible for vasoconstriction during hemostasis?

  • Platelets (correct)
  • Tissue factor
  • Fibrinolysis
  • Complement inhibitors

Which of the following factors is NOT synthesized by the liver?

  • Factor V
  • Factor VIII
  • Factor II
  • Factor XI (correct)

Which of the following is responsible for converting fibrinogen to fibrin?

<p>Thrombin (A)</p> Signup and view all the answers

Which of the following is NOT a function of coagulation factors?

<p>Platelet activation (B)</p> Signup and view all the answers

Which of the following is responsible for platelet aggregation?

<p>Thrombin (A)</p> Signup and view all the answers

Which of the following is responsible for regulating coagulation reactions?

<p>Factor V (B)</p> Signup and view all the answers

Which of the following is responsible for the formation of platelets?

<p>Megakaryocyte (D)</p> Signup and view all the answers

Which of the following is NOT a step in the process of hemostasis?

<p>Initiation of fibrinolysis (D)</p> Signup and view all the answers

Which factor deficiency was identified in John Hageman?

<p>Factor XII deficiency (D)</p> Signup and view all the answers

What was the cause of John Hageman's death?

<p>Pulmonary embolism (B)</p> Signup and view all the answers

What is the physiological activator of normal hemostasis?

<p>Factor VIIa (B)</p> Signup and view all the answers

Which protein is a major physiological inhibitor of coagulation?

<p>Protein C (A)</p> Signup and view all the answers

What is the role of Protein S?

<p>Cofactor for Protein C (B)</p> Signup and view all the answers

What is the function of Activated Protein C (APC)?

<p>Inactivates Factors V and VIII (A)</p> Signup and view all the answers

What does the TFPI/FXa complex inhibit?

<p>TF/FVIIa (D)</p> Signup and view all the answers

What is the role of Antithrombin III?

<p>Binds and inhibits Thrombin (IIa) and active clotting Factors Xa, IXa, XIa (A)</p> Signup and view all the answers

What increases the activity of Antithrombin III by several thousand-fold?

<p>Heparin (D)</p> Signup and view all the answers

What is a rare disorder characterized by Congenital ATIII deficiency?

<p>Protein C deficiency (B)</p> Signup and view all the answers

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