Male Hormones
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Questions and Answers

Which hormone is responsible for negative feedback in the hypothalamus?

  • Testosterone
  • Estrogen (correct)
  • DHT
  • Androstenedione

What is the primary hormone secreted by the testis?

  • Dehydroepiandrosterone
  • Androstenedione
  • DHT
  • Testosterone (correct)

Which enzyme converts testosterone to DHT in certain tissues?

  • GnRH
  • 5alpha-reductase (correct)
  • SHBG
  • Aromatase

What is the main function of inhibin secreted by Sertoli cells?

<p>Negative feedback to FSH release (C)</p> Signup and view all the answers

Which hormone drives the process of spermatogenesis?

<p>Testosterone (C)</p> Signup and view all the answers

What are the secondary sex characteristics in males primarily influenced by?

<p>Testosterone (D)</p> Signup and view all the answers

Which hormone is responsible for the release of gonadotropins from the anterior pituitary?

<p>GnRH (D)</p> Signup and view all the answers

What is the main function of LH in males?

<p>Stimulate testosterone production (B)</p> Signup and view all the answers

Which hormone provides negative feedback to LH release and GnRH release?

<p>Testosterone (D)</p> Signup and view all the answers

What percentage of testosterone is bound to SHBG?

<p>65% (B)</p> Signup and view all the answers

Which of the following is a key target organ for the effects of testosterone?

<p>Brain (A)</p> Signup and view all the answers

What is the main use of androgen replacement therapy in men?

<p>Treatment of hypogonadism (A)</p> Signup and view all the answers

Which of the following is an adverse effect of androgen suppression with finasteride?

<p>Gynecomastia (D)</p> Signup and view all the answers

What is the main difference between bicalutamide and enzalutamide?

<p>Bicalutamide is a partial agonist, while enzalutamide is a full antagonist (C)</p> Signup and view all the answers

What is the main adverse effect of androgen receptor antagonists used for prostate cancer?

<p>Hot flashes (C)</p> Signup and view all the answers

What is the main symptom of erectile dysfunction?

<p>Inability to maintain penile erection (D)</p> Signup and view all the answers

What is the main effect of testosterone on muscle?

<p>Increase in strength and volume (C)</p> Signup and view all the answers

What is the main effect of testosterone on bone?

<p>Closure of epiphyses (C)</p> Signup and view all the answers

What is the main effect of testosterone on the liver?

<p>Synthesis of serum proteins (A)</p> Signup and view all the answers

Which type of erectile tissue surrounds the urethra and expands to form the bulb of the penis?

<p>Corpus spongiosum (A)</p> Signup and view all the answers

What causes the enlargement and stiffening of the penis during an erection?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a side effect of older ED therapy using alprostadil (PGE1)?

<p>Nasal congestion (C)</p> Signup and view all the answers

Which oral PDE inhibitor has the longest duration of action according to the text?

<p>Tadalafil (C)</p> Signup and view all the answers

Which of the following is NOT a common side effect of oral PDE inhibitors?

<p>Abdominal pain/GI distress (A)</p> Signup and view all the answers

Which of the following drugs is contraindicated with organic nitrates according to the text?

<p>Sildenafil (D)</p> Signup and view all the answers

Which oral PDE inhibitor has the shortest time to peak concentration according to the text?

<p>Avanafil (D)</p> Signup and view all the answers

Which of the following is NOT a food interaction with oral PDE inhibitors according to the text?

<p>Tadalafil (B)</p> Signup and view all the answers

Which type of erectile tissue forms the paired dorsal erectile bodies?

<p>Corpora cavernosa (B)</p> Signup and view all the answers

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