Male Hormones
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Questions and Answers

Which hormone is responsible for negative feedback in the hypothalamus?

  • Testosterone
  • Estrogen (correct)
  • DHT
  • Androstenedione
  • What is the primary hormone secreted by the testis?

  • Dehydroepiandrosterone
  • Androstenedione
  • DHT
  • Testosterone (correct)
  • Which enzyme converts testosterone to DHT in certain tissues?

  • GnRH
  • 5alpha-reductase (correct)
  • SHBG
  • Aromatase
  • What is the main function of inhibin secreted by Sertoli cells?

    <p>Negative feedback to FSH release</p> Signup and view all the answers

    Which hormone drives the process of spermatogenesis?

    <p>Testosterone</p> Signup and view all the answers

    What are the secondary sex characteristics in males primarily influenced by?

    <p>Testosterone</p> Signup and view all the answers

    Which hormone is responsible for the release of gonadotropins from the anterior pituitary?

    <p>GnRH</p> Signup and view all the answers

    What is the main function of LH in males?

    <p>Stimulate testosterone production</p> Signup and view all the answers

    Which hormone provides negative feedback to LH release and GnRH release?

    <p>Testosterone</p> Signup and view all the answers

    What percentage of testosterone is bound to SHBG?

    <p>65%</p> Signup and view all the answers

    Which of the following is a key target organ for the effects of testosterone?

    <p>Brain</p> Signup and view all the answers

    What is the main use of androgen replacement therapy in men?

    <p>Treatment of hypogonadism</p> Signup and view all the answers

    Which of the following is an adverse effect of androgen suppression with finasteride?

    <p>Gynecomastia</p> Signup and view all the answers

    What is the main difference between bicalutamide and enzalutamide?

    <p>Bicalutamide is a partial agonist, while enzalutamide is a full antagonist</p> Signup and view all the answers

    What is the main adverse effect of androgen receptor antagonists used for prostate cancer?

    <p>Hot flashes</p> Signup and view all the answers

    What is the main symptom of erectile dysfunction?

    <p>Inability to maintain penile erection</p> Signup and view all the answers

    What is the main effect of testosterone on muscle?

    <p>Increase in strength and volume</p> Signup and view all the answers

    What is the main effect of testosterone on bone?

    <p>Closure of epiphyses</p> Signup and view all the answers

    What is the main effect of testosterone on the liver?

    <p>Synthesis of serum proteins</p> Signup and view all the answers

    Which type of erectile tissue surrounds the urethra and expands to form the bulb of the penis?

    <p>Corpus spongiosum</p> Signup and view all the answers

    What causes the enlargement and stiffening of the penis during an erection?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is NOT a side effect of older ED therapy using alprostadil (PGE1)?

    <p>Nasal congestion</p> Signup and view all the answers

    Which oral PDE inhibitor has the longest duration of action according to the text?

    <p>Tadalafil</p> Signup and view all the answers

    Which of the following is NOT a common side effect of oral PDE inhibitors?

    <p>Abdominal pain/GI distress</p> Signup and view all the answers

    Which of the following drugs is contraindicated with organic nitrates according to the text?

    <p>Sildenafil</p> Signup and view all the answers

    Which oral PDE inhibitor has the shortest time to peak concentration according to the text?

    <p>Avanafil</p> Signup and view all the answers

    Which of the following is NOT a food interaction with oral PDE inhibitors according to the text?

    <p>Tadalafil</p> Signup and view all the answers

    Which type of erectile tissue forms the paired dorsal erectile bodies?

    <p>Corpora cavernosa</p> Signup and view all the answers

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