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Questions and Answers
What is the purpose of sequence alignment?
What is a query sequence?
What is a reference sequence?
What does sequence alignment measure?
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What is the difference between global and local alignment?
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What is homology?
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What is pairwise sequence alignment?
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Study Notes
- Sequence alignment is a bioinformatic method used for functional and evolutionary inference.
- It involves arranging sequences to identify regions of similarity.
- Query sequence is an unknown sequence to be aligned to a known sequence.
- Reference sequence is the known sequence the query is aligned to.
- Sequence alignment measures similarity, determines residue-residue correspondences, observes patterns of conservation and variability, and infers evolutionary relationships.
- Global alignment aligns entire sequences, while local alignment aligns regions with high similarity.
- Identity and similarity are measures of how close two sequences are.
- Homology implies an evolutionary relationship and is established on the basis of measured similarity or identity.
- Pairwise sequence alignment arranges two sequences in two rows and uses gaps to find the best match.
- Dotplot alignment is a type of pairwise sequence alignment.
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Description
Test your knowledge of sequence alignment with this quiz! Learn about the different types of sequences, the methods used for alignment, and the insights gained from analyzing sequence data. From global to local alignment, and from identity to homology, this quiz covers everything you need to know about sequence alignment. Get ready to improve your bioinformatic skills and become an expert in sequence alignment!
