Podcast
Questions and Answers
What is the primary mechanism by which mast cell stabilizers like cromolyn reduce inflammation in asthma?
What is the primary mechanism by which mast cell stabilizers like cromolyn reduce inflammation in asthma?
- Increasing the production of mucus to trap inflammatory agents.
- Directly attacking and neutralizing foreign cells in the airways.
- Preventing the release of leukotrienes and histamine from mast cells. (correct)
- Dilating the bronchioles to improve airflow directly.
A patient is prescribed cromolyn for long-term management of allergy-related asthma. How should the nurse counsel the patient regarding the expected onset of therapeutic effects?
A patient is prescribed cromolyn for long-term management of allergy-related asthma. How should the nurse counsel the patient regarding the expected onset of therapeutic effects?
- The medication provides immediate relief, similar to a bronchodilator.
- The medication starts working within 24 hours.
- It may take several weeks of regular use to achieve the full therapeutic effects. (correct)
- Therapeutic effects are typically noticeable within the first few days of use.
A client with seasonal allergic rhinitis is prescribed cromolyn. What is the correct route of administration for this condition?
A client with seasonal allergic rhinitis is prescribed cromolyn. What is the correct route of administration for this condition?
- Intravenous infusion
- Intranasal instillation (correct)
- Oral tablet
- Subcutaneous injection
A patient is using cromolyn to prevent exercise-induced bronchospasm (EIB). Which instruction should the nurse provide regarding the timing of medication administration?
A patient is using cromolyn to prevent exercise-induced bronchospasm (EIB). Which instruction should the nurse provide regarding the timing of medication administration?
A patient using a mast cell stabilizer reports experiencing a mild cough after inhalation. What is the most appropriate initial nursing intervention?
A patient using a mast cell stabilizer reports experiencing a mild cough after inhalation. What is the most appropriate initial nursing intervention?
Which statement accurately describes the role of mast cell stabilizers in treating acute asthma attacks?
Which statement accurately describes the role of mast cell stabilizers in treating acute asthma attacks?
What should the nurse prioritize when educating a client on the use of mast cell stabilizers for managing asthma?
What should the nurse prioritize when educating a client on the use of mast cell stabilizers for managing asthma?
A client using cromolyn reports sudden rash, swelling of the mouth, and wheezing shortly after using the inhaler. What is the priority nursing action?
A client using cromolyn reports sudden rash, swelling of the mouth, and wheezing shortly after using the inhaler. What is the priority nursing action?
Flashcards
Mast Cell Stabilizers
Mast Cell Stabilizers
Anti-inflammatory inhalants that prevent the release of leukotrienes and histamine to reduce bronchial inflammation.
Cromolyn
Cromolyn
Cromolyn is a prototype medication of mast cell stabilizers.
Cromolyn action
Cromolyn action
Cromolyn prevents release of leukotrienes and histamine, which minimizes inflammation and edema in airways but does not have bronchodilation effects.
Cromolyn Adverse Effects
Cromolyn Adverse Effects
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Cromolyn Contraindication
Cromolyn Contraindication
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Cromolyn Administration
Cromolyn Administration
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EIB Prevention
EIB Prevention
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Seasonal Allergy Use
Seasonal Allergy Use
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Study Notes
- Mast cell stabilizers are anti-inflammatory inhalants that reduce bronchial inflammation in mild to moderate asthma.
- They are used to treat long-term allergy-related asthma.
- They prevent exercise-induced bronchospasm (EIB) and seasonal allergy manifestations.
- They help manage allergic rhinitis through intranasal instillation.
Prototype Medication
- Cromolyn is the prototype mast cell stabilizer.
Pharmacologic Action
- Mast cell stabilizers suppress inflammation similarly to corticosteroids.
- They prevent the release of leukotrienes and histamine, which mediate inflammation.
- They prevent white blood cells (leukocytes and eosinophils) from stimulating the inflammatory response.
- They minimize the actions of inflammatory cells, decreasing inflammation and edema of the airways.
- They do not have bronchodilation effects.
Adverse Drug Reactions
- Cromolyn is one of the safest antiasthma medications, with minimal adverse drug reactions.
- Cough or bronchospasm may occur in fewer than 1 in 10,000 clients.
Interventions
- Cromolyn is contraindicated in clients with a previous allergic response to the medication.
Administration
- Administer mast cell stabilizers with a power-driven nebulizer.
- The initial dosage is 20 mg four times daily, maintained at the lowest effective dosage.
- To prevent EIB, administer 10 to 15 minutes before activity, no sooner than 1 hour prior.
- To avoid seasonal allergies, take cromolyn prior to exposure.
Client Instructions
- Take as prescribed for prevention of asthma exacerbations.
- This medication is not effective against acute asthma attacks.
- It may take several weeks to achieve therapeutic effects.
Safety Alert
- Although severe allergic reactions are rare, instruct clients to seek immediate medical care for sudden rash, swelling of the mouth or throat, or wheezing after use.
Contraindications and Precautions
- Mast cell stabilizers are contraindicated in clients allergic to cromolyn.
Interactions
- There are no known medication or food interactions with mast cell stabilizers.
Question Answer
- Correct answer is A: Take the medication 15 minutes before exercising.
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Description
Mast cell stabilizers are anti-inflammatory inhalants used for mild to moderate asthma, preventing leukotriene and histamine release. Cromolyn is a prototype medication. They help treat allergy-related asthma, exercise-induced bronchospasm, and allergic rhinitis.
