Podcast
Questions and Answers
What is the characteristic feature of MGUS?
What is the characteristic feature of MGUS?
- Presence of bone lesions
- Less than 10% of plasma cells in the marrow (correct)
- More than 10% of plasma cells in the marrow
- High levels of M spike
What is the primary mechanism of bone destruction in myeloma?
What is the primary mechanism of bone destruction in myeloma?
- Direct damage by plasma cells
- Osteoclast activation due to RANK-ligand upregulation (correct)
- Inflammation due to immune response
- Osteoblast inactivation due to parathyroid hormone
What is the characteristic histological feature of myeloma?
What is the characteristic histological feature of myeloma?
- Bone marrow replaced by sheets of plasma cells (correct)
- Follicular lymphoma with B cell proliferation
- Reactive lymph node hyperplasia
- Granulomatous inflammation
What is the primary clinical manifestation of renal involvement in myeloma?
What is the primary clinical manifestation of renal involvement in myeloma?
What is the most common type of lymphoma related to myeloma?
What is the most common type of lymphoma related to myeloma?
What is the median survival of untreated myeloma?
What is the median survival of untreated myeloma?
What is a characteristic of B cells in non-Hodgkin lymphomas?
What is a characteristic of B cells in non-Hodgkin lymphomas?
What is the primary site of manifestation for non-Hodgkin lymphomas, with few exceptions?
What is the primary site of manifestation for non-Hodgkin lymphomas, with few exceptions?
What is a common symptom of non-Hodgkin lymphomas?
What is a common symptom of non-Hodgkin lymphomas?
What is the term for unexplained weight loss, fever, or night sweats in non-Hodgkin lymphomas?
What is the term for unexplained weight loss, fever, or night sweats in non-Hodgkin lymphomas?
What is the term for a tumor that is widely disseminated at diagnosis?
What is the term for a tumor that is widely disseminated at diagnosis?
What is the association between Pylori and gastric MALToma?
What is the association between Pylori and gastric MALToma?
What is the primary treatment for MALT lymphoma?
What is the primary treatment for MALT lymphoma?
Which of the following is a characteristic histological feature of Mantle Cell Lymphoma?
Which of the following is a characteristic histological feature of Mantle Cell Lymphoma?
What is the primary etiological factor in endemic Burkitt lymphoma?
What is the primary etiological factor in endemic Burkitt lymphoma?
Which type of lymphoma is commonly associated with skin lesions?
Which type of lymphoma is commonly associated with skin lesions?
What is the primary clinical manifestation of Small Lymphocytic Lymphoma (SLL/CLL)?
What is the primary clinical manifestation of Small Lymphocytic Lymphoma (SLL/CLL)?
Which of the following is a characteristic feature of Mantle Cell Lymphoma?
Which of the following is a characteristic feature of Mantle Cell Lymphoma?
What is the primary treatment for Adult T-Cell Leukemia/Lymphoma (ATLL)?
What is the primary treatment for Adult T-Cell Leukemia/Lymphoma (ATLL)?
Which type of lymphoma is commonly associated with a t(11;18) translocation?
Which type of lymphoma is commonly associated with a t(11;18) translocation?
What is the primary clinical manifestation of Mycosis Fungoides?
What is the primary clinical manifestation of Mycosis Fungoides?
Which of the following is a characteristic feature of Burkitt lymphoma?
Which of the following is a characteristic feature of Burkitt lymphoma?