18 Questions
Which tablet processing method involves suspending materials in air while spraying a liquid binder?
Fluid Bed Granulation
What is the primary purpose of the sub-coating step in tableting?
To build up the tablet size
Which tablet coating method involves successive coating of a sucrose-based solution?
Sugar Coating
In tableting, what is the purpose of double compression in Dry Granulation?
To compact the powder mixture into large pieces
Which excipient type is critical for Direct Compression tablet processing?
Avicel®
What is the major disadvantage of Sugar Coating as a tablet coating method?
Leads to a large increase in tablet weight and is time-consuming
What is the recommended remedy for flaking in tablet manufacturing?
Add a polysorbate surfactant
Which type of capsules are manufactured separately from the filling operation?
Hard Gelatin Capsules
What method is used to mix heat-sensitive ointment bases during the manufacturing process?
Unguator® Electric Mortar and Pestle
What type of film surface is characterized by rough, non-glossy appearance in tablet manufacturing?
Orange Peel
Which substance is NOT considered a gelling agent according to the text?
Magnesium Aluminum Silicate
What is the purpose of using ointment roller mills in the manufacturing of ointments?
To mix heat-sensitive ointment bases
What is the purpose of the volatile solvent/vehicle in tablet manufacturing?
To improve spreadability of the film
Which substance is responsible for providing water solubility/permeability to the film in tablet manufacturing?
Cellulose acetate phthalate (CAP)
What is the main function of impression coating in tablet manufacturing?
Separates the tablet core from water
Which component is responsible for enhancing the spreadability of the film in tablet manufacturing?
Polysorbates (Tween)
What is the main advantage of sealcoating agents in tablet manufacturing?
Minimal increase in tablet weight
What is the primary function of bridging in tablet manufacturing?
Obscuring logo markings on tablets
Explore common issues in the manufacturing process of semisolid dosage forms such as tablet twinning, orange peel roughness, and flaking. Learn about the causes of these problems and their remedies.
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