Efficacy and Safety of Veterinary drugs

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Questions and Answers

Why is it important to manage client expectations when prescribing veterinary drugs?

  • To ensure clients do not ask too many questions
  • To help clients understand drug efficacy and potential limitations (correct)
  • To encourage clients to buy more expensive medications
  • To prevent the need for follow-up visits

What factors should be considered when deciding which veterinary drug to use?

Animal specific situations, client compliance, and extra-label drug use

What is a key consideration when handling incorrect drug administration in veterinary medicine?

  • Blame the owner for incorrect use
  • Immediately discontinue treatment without assessment
  • Assess the potential consequences and take appropriate corrective action (correct)
  • Ignore the mistake if the animal seems fine

Veterinary drugs are _______ that are used to ____, ______, _______, _______ or prevent _________

<p>Veterinary drugs are products that are used to diagnose, cure, mitigate, treat or prevent diseases.</p> Signup and view all the answers

What must a product have in order to be registered with the FDA?

<p>A claim for efficacy and safety at a certain dose (B)</p> Signup and view all the answers

Which of the following is NOT considered a drug unless combined with another drug?

<p>Non-systemic ectoparasiticides (D)</p> Signup and view all the answers

What other products are not considered drugs?

<p>Teat dips, cleaning agents, many topical hygiene products, vaccines, vitamins, herbal products, and supplements</p> Signup and view all the answers

What distinguishes a product from just an active compound?

<p>It includes a formulation with a specific claim (A)</p> Signup and view all the answers

How is efficacy defined?

<p>Disease-dependent and study-dependent (B)</p> Signup and view all the answers

Why is it difficult to compare two products with the same efficacy wording on the label?

<p>They may have been tested using different measurement methods (C)</p> Signup and view all the answers

How must a product demonstrate its efficacy for a specific indication?

<p>By showing effectiveness at the planned label dose in the target species (A)</p> Signup and view all the answers

What is the international standard for defining efficacy against parasites?

<p>A 90% decrease in worm numbers or egg count in feces (C)</p> Signup and view all the answers

What level of efficacy is required for a drug to be approved?

<p>It must show substantial evidence of efficacy, which varies depending on the disease (B)</p> Signup and view all the answers

Why would a product with lower efficacy be registered?

<p>Due to different measurements, Different mode of action and better safety principle</p> Signup and view all the answers

A P value of less than ____ means you have substantial evidence

<p>.05</p> Signup and view all the answers

What does "TAS" stand for in TAS studies?

<p>Target Animal Safety (B)</p> Signup and view all the answers

In TAS tolerance studies, which animals are typically used?

<p>Normal, healthy laboratory beagles</p> Signup and view all the answers

What dose levels are typically tested in TAS tolerance studies?

<p>1x, 3x, and 5x the recommended dose (B)</p> Signup and view all the answers

Why were beagles originally used in safety studies?

<p>They have uniform genetics, making results more consistent</p> Signup and view all the answers

Why is pharmacovigilance especially important in the first year after a product is released?

<p>Because real-world data from diverse animal populations may reveal unforeseen safety concerns (C)</p> Signup and view all the answers

What may happen to product labels at the end of the first year on the market?

<p>They are often updated based on real-world safety and efficacy data (B)</p> Signup and view all the answers

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