Managing Chest Pain, Ischemia and Myocardial Infarction
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Questions and Answers

A patient presents with a painful and swollen calf after a period of post-operative bed rest. Which of the following mechanisms is the MOST likely cause of this condition?

  • Sudden rupture of a Baker's cyst causing fluid buildup in the calf.
  • Increased production of clotting factors due to surgery-related stress.
  • Accumulation of blood in the valves of the calf muscles due to inactivity (correct)
  • Bacterial infection in the calf muscles leading to inflammation and swelling

Which of the following scenarios BEST illustrates the concept of Virchow's triad in the context of thrombosis?

  • A patient with a genetic predisposition to hemophilia experiences excessive bleeding after a minor injury.
  • A patient with atherosclerosis develops a thrombus due to changes in the vessel surface, blood flow, and blood composition. (correct)
  • A patient with a vitamin K deficiency develops impaired clotting function and prolonged bleeding times.
  • A patient who accidentally overdoses on warfarin experiences severe internal bleeding.

A patient is diagnosed with deep vein thrombosis (DVT). Which of the following statements BEST describes the potential consequences of this condition?

  • DVT leads to an increased risk of arterial blockage in the brain, causing stroke.
  • DVT can cause thrombus formation in the lower limb deep veins, obstructing flow and potentially releasing fragments into systemic circulation. (correct)
  • DVT primarily affects the superficial veins of the legs, causing cosmetic issues but posing no significant health risks.
  • DVT results in the formation of plaques in the coronary arteries, increasing the risk of myocardial infarction.

How would you differentiate thrombosis from normal clotting?

<p>Clotting leads to fibrin for healing, whereas thrombosis involves haemostasis occurring at an incorrect time and place. (B)</p> Signup and view all the answers

A patient is experiencing central, strangling chest pain radiating to the left arm, accompanied by nausea and sweating. An ECG shows ST elevation. Initial treatment should include which combination of the following?

<p>Oxygen, GTN, and Aspirin (B)</p> Signup and view all the answers

A patient with peripheral vascular disease experiences central chest pain during a dental procedure. After administering oxygen and GTN spray twice with a 10-minute interval, there is no improvement. What is the MOST appropriate next step?

<p>Call emergency services, administer chewed aspirin (300mg), and suspect a myocardial infarction. (B)</p> Signup and view all the answers

Which of the following sets of symptoms BEST describes the progression from angina to a potential myocardial infarction (MI)?

<p>Chest pain, shortness of breath, anxiety, pallor and sweating. (B)</p> Signup and view all the answers

Which of the following is the MOST LIKELY underlying cause of ischemic heart disease (IHD)?

<p>Atheromatous plaque within coronary arteries, causing constriction of blood flow. (C)</p> Signup and view all the answers

A patient experiencing angina pectoris describes the pain as a 'strangling feeling' in the chest, accompanied by breathlessness. Where else is the patient MOST LIKELY to experience referred pain?

<p>Left arm and jaw (A)</p> Signup and view all the answers

Which ECG finding is MOST indicative of an angina attack?

<p>ST depression (B)</p> Signup and view all the answers

A patient with ischemic heart disease (IHD) is taking multiple medications. Which medication is MOST LIKELY to cause a bleeding tendency during dental procedures?

<p>Aspirin (D)</p> Signup and view all the answers

Which of the following is the MOST significant factor determining the likelihood of tissue damage following arterial occlusion?

<p>Degree of arterial blocking (A)</p> Signup and view all the answers

A patient presents with a history of hypertension, diabetes, and smoking. To BEST reduce their risk of ischemic heart disease (IHD), which lifestyle modification should be PRIORITIZED?

<p>Smoking cessation. (B)</p> Signup and view all the answers

Flashcards

Ca channel blockers side effect?

Certain calcium channel blockers can cause an overgrowth of the gingival tissue.

MI symptoms (patient reported)?

Central chest pain > 15 mins, radiating pain, nausea/vomiting.

MI signs (observed)?

Grey tinge, sweating, and tachycardia (fast heart rate).

Clotting vs. Thrombosis?

Thrombosis involves both platelets and the clotting cascade which occurs in the wrong place and at the wrong time; clotting is just the cascade activating for healing.

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Virchow's Triad?

Changes to vessel surface, blood flow, and blood constituents.

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Managing Chest Pain in Dental Setting

  1. DRS ABC (Danger, Response, Send for help, Airway, Breathing, Circulation). 2. GTN spray. 3. Oxygen at 15L/min. 4. Repeat GTN after 10 mins. 5. If no response, call emergency services (assume MI). 6. Chew 300mg aspirin.
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Clinical Symptoms of Ischemia (3)

Angina, Transient Ischemic Attack (TIA), Peripheral Vascular Disease (intermittent claudication).

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Clinical Symptoms of Infarction (3)

Myocardial infarction, Stroke, Gangrene.

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Factors Influencing Ischemia/Infarction (4)

Collateral blood supply, Speed of arterial occlusion, Metabolic needs of tissue, Degree of arterial blocking.

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Ischemic Heart Disease (IHD) Cause

Atheromatous plaque in coronary arteries restricts blood flow leading to inadequate oxygen supply to the heart.

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IHD Progression

Plaque rupture leading to acute thrombus and myocardial infarction.

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Modifiable Risk Factors for IHD (9)

Hyperlipidaemia, Smoking, Hypertension, Diabetes, Obesity, Lack of exercise, High alcohol intake, Stress, OCP.

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Angina Pectoris

Reduced oxygen perfusion of cardiac muscle causing strangling chest pain, breathlessness, and pain radiating to jaw/left arm.

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Study Notes

  • Study notes on managing chest pain, ischemia, infarction, IHD, angina, myocardial infarction, clotting, thrombosis and deep vein thrombosis

Management of Central Chest Pain in Patients with Peripheral Vascular Disease During Dental Treatment

  • Follow DRS ABC (Danger, Response, Send for help, Airway, Breathing, Compressions)
  • Administer Glyceryl Trinitrate (GTN) spray
  • Give 15L/min oxygen
  • Repeat GTN after 10 minutes
  • If no response, call emergency services, suspecting myocardial infarction (MI)
  • Administer 300mg chewed aspirin
  • Radiating pain and shortness of breath indicate angina due to arterial stenosis from atherosclerosis
  • Radiating pain + shortness of breath + sweats + pallor + anxiety indicate MI
  • For MI, administer 300mg chewed aspirin and call emergency services
  • Consider relative analgesics like 50% oxygen and 50% nitrous oxide

Clinical Symptoms of Ischemia

  • Angina
  • Transient Ischemic Attack (TIA)
  • Peripheral vascular disease presenting as intermittent claudication (calf muscle pain)

Clinical Symptoms of Infarction

  • Myocardial infarction
  • Stroke
  • Gangrene (localized death and decomposition of body tissue)

Factors Influencing Ischemia/Infarction

  • Collateral blood supply
  • Speed of arterial occlusion
  • Metabolic needs of tissue
  • Degree of arterial blocking

Ischemic Heart Disease (IHD)

  • Caused by atheromatous plaque within coronary arteries constricting blood flow
  • Leads to inadequate oxygen supply to meet the heart's demands

Progression of IHD

  • Plaque rupture can lead to acute thrombus and myocardial infarction

Modifiable Risk Factors for IHD

  • Hyperlipidaemia
  • Smoking
  • Hypertension
  • Diabetes
  • Obesity
  • Lack of exercise
  • High alcohol intake
  • Stress
  • Oral contraceptive pill (OCP)

Angina Pectoris

  • Reduced oxygen perfusion of the cardiac muscle
  • Symptoms include a strangling feeling in the chest, breathlessness, and pain radiating to the jaw and left arm
  • ECG shows ST depression
  • Pain resolves in minutes following rest and GTN

Oral Cavity Effects of Angina/Myocardial Infarction Treatment (Polypharmacy)

  • Aspirin leads to bleeding tendency
  • Beta Blockers can cause lichenoid reactions
  • Calcium channel blockers can cause gingival overgrowth
  • Nicorandil can cause oral ulceration

Symptoms of Myocardial Infarction

  • Central strangling pain lasting longer than 15 minutes
  • Pain radiates to the neck, jaw, and left arm
  • Nausea and vomiting

Signs of Myocardial Infarction

  • Grey tinge
  • Sweating
  • Tachycardia

ECG and Treatment for Myocardial Infarction

  • ECG shows ST elevation
  • Treatment involves oxygen, GTN, aspirin, and Entonox

Clotting vs. Thrombosis

  • Thrombosis involves both platelets and the clotting cascade, while clotting mainly involves the cascade
  • Thrombosis is haemostasis occurring in the wrong place and at the wrong time
  • Thrombosis is harmful, while clotting leads to fibrin formation for healing

Deep Vein Thrombosis (DVT)

  • Prolonged inactivity can lead to blood accumulating in valves, especially in calf muscles, leading to DVT then embolus

Virchow's Triad (Factors Promoting Thrombosis)

  • Changes in the surface of the vessel
  • Changes in blood flow
  • Changes in the constituents of the blood

Vessel Surface Changes and Thrombosis

  • Atheromatous plaque causes loss of the endothelial layer
  • This leads to exposure of sub-endothelial tissues, triggering platelet and clotting cascade activation

Altered Blood Flow and Thrombosis

  • Inactivity leads to blood accumulation in valves, especially calf muscles, causing DVT and embolus

Characteristics of Deep Vein Thrombosis

  • Thrombus formation in lower limb deep veins
  • Thrombus enlarges and obstructs flow
  • May release fragments into systemic circulation

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Description

Study notes on managing chest pain, ischemia, infarction, IHD, angina, myocardial infarction, clotting, thrombosis and deep vein thrombosis. Includes when to administer Glyceryl Trinitrate (GTN) spray or call emergency services.

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