Management of Obstructive Jaundice

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Questions and Answers

What is the first step in managing a patient with suspected obstructive jaundice?

  • Administer broad spectrum IV antibiotics
  • Discuss for admission and work-up in hospital (correct)
  • Perform surgical intervention immediately
  • Test INR levels immediately

Which antibiotic is suggested for patients with cholangitis who are allergic to Penicillin?

  • Augmentin
  • Clindamycin
  • Ciprofloxacin (correct)
  • Amoxicillin

What is the purpose of administering Vitamin K to patients with obstructive jaundice?

  • To control infection
  • To decrease pain levels
  • To improve renal function
  • To manage bleeding risk associated with elevated INR (correct)

What complication must be carefully monitored in patients with obstructive jaundice?

<p>Dehydration leading to acute kidney injury (A)</p> Signup and view all the answers

What is the role of stents in managing obstructive jaundice?

<p>To relieve obstructions in unresectable cases (A)</p> Signup and view all the answers

Which of the following procedures might be performed if a malignant lesion is deemed resectable?

<p>Pancreatico-duodenectomy (A)</p> Signup and view all the answers

What is a common presentation indicating a patient has cholangitis?

<p>Fever and rigors or raised white cell count (B)</p> Signup and view all the answers

What should be avoided in treating patients with obstructive jaundice who have cardiac conditions?

<p>Intravenous fluids overload (A)</p> Signup and view all the answers

What is the preferred time frame for scheduling surgery (Cholecystectomy) for Acute Cholecystitis at TBH?

<p>Within 3-4 days (D)</p> Signup and view all the answers

Which of the following is not an indication for urgent surgery for Acute Cholecystitis?

<p>Jaundice due to bile duct obstruction (C)</p> Signup and view all the answers

What alternative policy was used in previous years for treating Acute Cholecystitis?

<p>Medical therapy followed by elective surgery in 6 weeks (B)</p> Signup and view all the answers

What is a critically ill patient's treatment option if not fit for cholecystectomy?

<p>Percutaneous cholecystostomy (A)</p> Signup and view all the answers

What is the prognosis for carcinoma of the gallbladder if discovered before spreading beyond the wall?

<p>Best if incidentally discovered on histology (C)</p> Signup and view all the answers

What is indicated by perforation of the gallbladder?

<p>Cholecystostomy is temporary (C)</p> Signup and view all the answers

Which of the following symptoms is associated with advanced gallbladder carcinoma?

<p>Obstructive jaundice (C)</p> Signup and view all the answers

What is the outcome of untreated advanced gallbladder carcinoma?

<p>Poor prognosis and minimal therapy options (D)</p> Signup and view all the answers

What is the primary management approach for patients suspected of having cholangitis?

<p>Antibiotic administration and prevention of dehydration (B)</p> Signup and view all the answers

Which of the following is NOT a symptom commonly associated with cholangitis?

<p>Nausea (B)</p> Signup and view all the answers

During the diagnosis of common bile duct stones, what ultrasound finding supports the diagnosis?

<p>Dilation of the CBD greater than 7mm (C)</p> Signup and view all the answers

What should happen if a patient with suspected CBD stones shows relief of colic and normalization of bilirubin levels?

<p>Schedule a same-admission laparoscopic cholecystectomy. (C)</p> Signup and view all the answers

Which component is NOT part of Reynold’s pentad in the context of cholangitis?

<p>Abdominal distension (B)</p> Signup and view all the answers

What is one of the primary indications for performing a cholecystectomy in patients with gallstones?

<p>To eliminate symptoms associated with gallstones (D)</p> Signup and view all the answers

What is the typical course of action for patients who do not show improvement in symptoms of cholangitis?

<p>Schedule an ERCP to remove the CBD stone (A)</p> Signup and view all the answers

Which surgical procedure is preferred for the treatment of symptomatic gallstones?

<p>Laparoscopic cholecystectomy (C)</p> Signup and view all the answers

What does the sensitivity of ultrasound for diagnosing common bile duct stones approximate?

<p>40% (A)</p> Signup and view all the answers

What is a common complication associated with cholecystectomy?

<p>Post-operative bleeding (B)</p> Signup and view all the answers

In patients managed for cholangitis, which test is considered unnecessary and expensive to repeat daily?

<p>Full liver function tests (C)</p> Signup and view all the answers

What is the most common organism found in cases of acute cholecystitis?

<p>Escherichia coli (A)</p> Signup and view all the answers

Which method is typically employed to manage acute cholecystitis according to established guidelines?

<p>IV fluids, analgesia, and broad spectrum antibiotics (B)</p> Signup and view all the answers

What is a contraindication for cholecystectomy in symptomatic patients?

<p>Poor performance status unfit for general anesthesia (C)</p> Signup and view all the answers

Which of the following antibiotics are recommended for treating acute cholecystitis?

<p>Ciprofloxacin and Metronidazole (C)</p> Signup and view all the answers

Which condition may necessitate surgical intervention by bypassing the bile duct?

<p>Chronic pancreatitis with biliary compression (A)</p> Signup and view all the answers

What characterizes mild cholangitis?

<p>Patient responds well to antibiotics and IV fluid administration. (A)</p> Signup and view all the answers

Which of the following is a common management approach for severe cholangitis?

<p>High-care setting with close monitoring, fluids, and antibiotics. (D)</p> Signup and view all the answers

What is a common presentation of intrahepatic cholangiocarcinoma?

<p>Weight loss with right upper quadrant abdominal pain. (D)</p> Signup and view all the answers

Where do Klatskin tumors typically occur?

<p>At the biliary confluence in the hepatic hilum. (A)</p> Signup and view all the answers

Which symptom is NOT typical of intrahepatic cholangiocarcinoma?

<p>Jaundice. (A)</p> Signup and view all the answers

What could be a potential treatment conducted if a patient with severe cholangitis does not respond to initial treatment?

<p>Cholecystostomy as a drainage option. (A)</p> Signup and view all the answers

Once diagnosed, how is cholangiocarcinoma typically managed?

<p>Patients are staged and treatment assigned based on resectability and fitness. (B)</p> Signup and view all the answers

What is NOT a typical method for biliary drainage in severe cholangitis?

<p>Laparoscopic cholecystectomy. (B)</p> Signup and view all the answers

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Study Notes

Management of Obstructive Jaundice

  • Admission and work-up necessary upon suspicion of obstructive jaundice; patients may be critically ill.
  • Resuscitation includes intravenous fluids, antibiotics, and analgesia.
  • Fever or raised white cell count indicates cholangitis; requires urgent treatment.
  • Broad-spectrum IV antibiotics (e.g., Augmentin, Ciprofoxacin, Metronidazole) administered for cholangitis.
  • Vitamin K (5-10mg IV) given if INR is elevated or jaundice is not relieved promptly.
  • Patients at risk of acute kidney injury must be carefully hydrated; avoid dehydration.
  • Interventions are required to relieve obstruction and address underlying causes (e.g., tumors).
  • Stents may be placed via ERCP or PTC for unresectable tumors or strictures due to conditions like chronic pancreatitis.
  • Surgical bypass may involve creating an anastomosis between bile duct and small bowel (Roux-en-Y Hepatico-jejunostomy).

Symptomatic Gallstones

  • Symptoms typically precede complications such as acute cholecystitis and pancreatitis.
  • Indication for cholecystectomy arises once gallstones are confirmed as the cause of symptoms.
  • Laparoscopic cholecystectomy is the preferred treatment; contraindications include poor performance status and patient refusal.
  • Complications of cholecystectomy may include bleeding, bile leaks, and bile duct injuries.

Management of Acute Cholecystitis

  • Diagnosis and severity based on Tokyo Guidelines; requires hospital admission, IV fluid resuscitation, and broad-spectrum antibiotics.
  • Opioids are typically required for pain relief.
  • Common organisms include E. coli and Klebsiella; treatment options include Augmentin and metronidazole.
  • Surgery (cholecystectomy) should be scheduled within 3-4 days; severe cases may require urgent intervention.
  • Critically ill patients may need percutaneous cholecystostomy as a temporary measure before surgical intervention.

Carcinoma of the Gallbladder

  • Poor prognosis once spread beyond the gallbladder wall; best outcomes if discovered incidentally post-cholecystectomy.
  • Advanced disease commonly presents with jaundice or metastases; few treatment options available.

Bile Duct Obstruction and Cholangitis

  • Obstruction results in obstructive jaundice; sepsis management parallels cholangitis protocols.
  • High risk of severe sepsis; antibiotics and hydration are crucial.
  • Common bile duct stones typically present with obstructive jaundice diagnosed via ultrasound.
  • Conservative management for suspected CBD stones; surgery planned once symptoms improve or after stone removal by ERCP.

Cholangitis

  • Life-threatening condition; severity may not correlate with bilirubin levels.
  • Charcot's triad (fever, jaundice, abdominal pain) and Reynold's pentad (hypotension, confusion) are key diagnostic criteria.
  • Mild cholangitis managed with fluids, antibiotics, and symptom monitoring; severe cases require biliary drainage.

Cholangiocarcinoma

  • Adenocarcinoma can occur in intrahepatic or extrahepatic bile ducts.
  • Intrahepatic cases often present with liver mass and abdominal pain, not jaundice.
  • Extrahepatic cases (perihilar or distal) present with painless obstructive jaundice.
  • Treatment involves assessing resectability and metastases post-diagnosis.

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