Podcast
Questions and Answers
What is the primary factor that regulates the descent of the testis from the posterior abdominal wall to the lower abdomen near the inguinal ring?
What is the primary factor that regulates the descent of the testis from the posterior abdominal wall to the lower abdomen near the inguinal ring?
Which abnormality in the descent process can result in the failure of one or both testes to descend properly?
Which abnormality in the descent process can result in the failure of one or both testes to descend properly?
Where is the internal (deep) ring located in the inguinal canal?
Where is the internal (deep) ring located in the inguinal canal?
Which tissue expresses the androgen receptors primarily in the testicular and epididymal regions?
Which tissue expresses the androgen receptors primarily in the testicular and epididymal regions?
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What stimulates Leydig cells to produce androgens, predominantly testosterone, for male development?
What stimulates Leydig cells to produce androgens, predominantly testosterone, for male development?
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Which hormone plays a role in regulating the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland?
Which hormone plays a role in regulating the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland?
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What is the primary site of androgen receptors in the prostate?
What is the primary site of androgen receptors in the prostate?
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What is the main effect of testosterone on Sertoli cells in the testis?
What is the main effect of testosterone on Sertoli cells in the testis?
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What is the role of hypothalamus in regulating male reproduction?
What is the role of hypothalamus in regulating male reproduction?
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Which phase of testes descent is regulated by mechanical factors, pressure changes within the abdominal cavity, and androgens such as testosterone?
Which phase of testes descent is regulated by mechanical factors, pressure changes within the abdominal cavity, and androgens such as testosterone?
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What is the legal duty of those who own or are responsible for a horse under the Animal Welfare Act (2013)?
What is the legal duty of those who own or are responsible for a horse under the Animal Welfare Act (2013)?
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What are some major welfare issues facing horses in the UK?
What are some major welfare issues facing horses in the UK?
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What tests can be performed to identify a 'rig' in horses?
What tests can be performed to identify a 'rig' in horses?
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What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
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What factors contribute to the variation in the cost of castration for horses?
What factors contribute to the variation in the cost of castration for horses?
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What should be included in the cost of castration for horses under general anaesthetic?
What should be included in the cost of castration for horses under general anaesthetic?
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What is included in the requirement for horse passports?
What is included in the requirement for horse passports?
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What is the purpose of microchipping horses?
What is the purpose of microchipping horses?
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At what age should foals have a valid passport and microchip according to legal requirements?
At what age should foals have a valid passport and microchip according to legal requirements?
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What happens if a horse does not have an up-to-date passport according to legal requirements?
What happens if a horse does not have an up-to-date passport according to legal requirements?
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What is the purpose of using a horse weight tape?
What is the purpose of using a horse weight tape?
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Why is it important for testes to be stored in the scrotum outside of the body cavity?
Why is it important for testes to be stored in the scrotum outside of the body cavity?
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At what temperature does spermatogenesis cease to function in most domesticated species?
At what temperature does spermatogenesis cease to function in most domesticated species?
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Where do the testicles initially develop in domestic animals?
Where do the testicles initially develop in domestic animals?
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What is the primary purpose of using a weight tape in conjunction with BCS for horses?
What is the primary purpose of using a weight tape in conjunction with BCS for horses?
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What is the retroperitoneal position of the testicles?
What is the retroperitoneal position of the testicles?
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In cryptorchid animals, where may the undescended testes be located?
In cryptorchid animals, where may the undescended testes be located?
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Why is it necessary for spermatogenesis to occur at a lower temperature in domestic animals?
Why is it necessary for spermatogenesis to occur at a lower temperature in domestic animals?
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What aspect of horses' conformation is crucial for accurate measurement with a weight tape?
What aspect of horses' conformation is crucial for accurate measurement with a weight tape?
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Within which cavity do the testes normally reside in domestic animals?
Within which cavity do the testes normally reside in domestic animals?
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Which of the following is NOT a function of the accessory sex glands in the male reproductive system?
Which of the following is NOT a function of the accessory sex glands in the male reproductive system?
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What physiological mechanism leads to the filling of the cavernous spaces in the erectile tissue during penile erection?
What physiological mechanism leads to the filling of the cavernous spaces in the erectile tissue during penile erection?
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What is the primary mechanism for sperm transport in the male reproductive tract?
What is the primary mechanism for sperm transport in the male reproductive tract?
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What is the main function of the epididymis in the male reproductive system?
What is the main function of the epididymis in the male reproductive system?
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Which behavioural change is most likely to be observed in a mature gelding after castration?
Which behavioural change is most likely to be observed in a mature gelding after castration?
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What is a key reason for castration of male horses?
What is a key reason for castration of male horses?
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What should be taken into consideration when assessing safety implications for handlers when examining an unhandled horse?
What should be taken into consideration when assessing safety implications for handlers when examining an unhandled horse?
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"A horse exhibiting aggressive type behavior poses a risk of ____________ to handlers."
"A horse exhibiting aggressive type behavior poses a risk of ____________ to handlers."
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"What is NOT a health and safety risk associated with handling unhandled horses?"
"What is NOT a health and safety risk associated with handling unhandled horses?"
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"What is NOT a function of prenatal androgens in masculinising the male reproductive system?"
"What is NOT a function of prenatal androgens in masculinising the male reproductive system?"
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Match the major welfare issues facing horses in the UK with their descriptions:
Match the major welfare issues facing horses in the UK with their descriptions:
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Match the tests used to identify a 'rig' in horses with their descriptions:
Match the tests used to identify a 'rig' in horses with their descriptions:
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Match the costs involved in castration for horses with their descriptions:
Match the costs involved in castration for horses with their descriptions:
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Match the legal requirements for identification of horses by microchip and passport with their descriptions:
Match the legal requirements for identification of horses by microchip and passport with their descriptions:
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It is a legal requirement to have ______ and passports for horses.
It is a legal requirement to have ______ and passports for horses.
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A male horse that has no signs of external testicles but still has one or two testicles present is known as a 'rig' or has ______.
A male horse that has no signs of external testicles but still has one or two testicles present is known as a 'rig' or has ______.
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AMH, produced by Sertoli cells, is a biomarker used to differentiate between cryptorchid and castrated horses and is tested through a ______.
AMH, produced by Sertoli cells, is a biomarker used to differentiate between cryptorchid and castrated horses and is tested through a ______.
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The retention of one or both testicles resulting in a true rig is known as ______.
The retention of one or both testicles resulting in a true rig is known as ______.
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Horses showing rig-like behavior can be tested with blood tests for the presence of ______.
Horses showing rig-like behavior can be tested with blood tests for the presence of ______.
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Equine testes produce 10 times as much ______ as testosterone.
Equine testes produce 10 times as much ______ as testosterone.
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Horses over 18 months of age should have a ______ of blood in a plain (clot) tube for a specific test.
Horses over 18 months of age should have a ______ of blood in a plain (clot) tube for a specific test.
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A single test of ______ will distinguish between rigs and geldings.
A single test of ______ will distinguish between rigs and geldings.
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Horses over 3 years of age should have ______ of blood in a plain (clot) tube for a specific test.
Horses over 3 years of age should have ______ of blood in a plain (clot) tube for a specific test.
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Foals should have a valid passport and microchip before they reach ______ old, according to legal requirements.
Foals should have a valid passport and microchip before they reach ______ old, according to legal requirements.
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What is the purpose of using a horse weight tape?
What is the purpose of using a horse weight tape?
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Why is the scrotal location of testes important in domestic animals?
Why is the scrotal location of testes important in domestic animals?
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What is the significance of the temperature dependence of spermatogenesis in domestic animals?
What is the significance of the temperature dependence of spermatogenesis in domestic animals?
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Where do the testicles initially develop in domestic animals?
Where do the testicles initially develop in domestic animals?
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What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
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Where may the undescended testes be located in cryptorchid animals?
Where may the undescended testes be located in cryptorchid animals?
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What is the main effect of testosterone on Sertoli cells in the testis?
What is the main effect of testosterone on Sertoli cells in the testis?
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What is the primary factor that regulates the descent of the testis from the posterior abdominal wall to the lower abdomen near the inguinal ring?
What is the primary factor that regulates the descent of the testis from the posterior abdominal wall to the lower abdomen near the inguinal ring?
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What is the role of hypothalamus in regulating male reproduction?
What is the role of hypothalamus in regulating male reproduction?
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At what temperature does spermatogenesis cease to function in most domesticated species?
At what temperature does spermatogenesis cease to function in most domesticated species?
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What ligaments are responsible for holding the testes in place during the descent process?
What ligaments are responsible for holding the testes in place during the descent process?
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What is the main role of the internal (deep) ring in the inguinal canal?
What is the main role of the internal (deep) ring in the inguinal canal?
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Where are the main general locations of the androgen receptors in the male reproductive system?
Where are the main general locations of the androgen receptors in the male reproductive system?
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What is the main role of the hypothalamus in the regulation of male reproduction?
What is the main role of the hypothalamus in the regulation of male reproduction?
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What is the primary effect of testosterone on Sertoli cells in the testis?
What is the primary effect of testosterone on Sertoli cells in the testis?
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What is the main effect of androgens on male sexual behavior?
What is the main effect of androgens on male sexual behavior?
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What are the two phases of testes descent, and what regulates the movement during each phase?
What are the two phases of testes descent, and what regulates the movement during each phase?
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What abnormality in the descent process can result in the failure of one or both testes to descend properly?
What abnormality in the descent process can result in the failure of one or both testes to descend properly?
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What is the main site of androgen receptors in the prostate?
What is the main site of androgen receptors in the prostate?
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What hormone stimulates Leydig cells to produce androgens for male development?
What hormone stimulates Leydig cells to produce androgens for male development?
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Explain the physiological mechanisms underlying penile erection.
Explain the physiological mechanisms underlying penile erection.
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Discuss the reasons for castration of male horses.
Discuss the reasons for castration of male horses.
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Outline the behavioural changes associated with castration in horses.
Outline the behavioural changes associated with castration in horses.
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Describe the absorptive and secretory functions of the male reproductive tract and accessory glands.
Describe the absorptive and secretory functions of the male reproductive tract and accessory glands.
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Describe the health and safety risks associated with handling aggressive type behavior/unhandled horses and discuss strategies for safe handling during a physical examination.
Describe the health and safety risks associated with handling aggressive type behavior/unhandled horses and discuss strategies for safe handling during a physical examination.
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Discuss the mechanisms for sperm transport in the male reproductive tract.
Discuss the mechanisms for sperm transport in the male reproductive tract.
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Explain the reabsorptive process of sperm in the male reproductive system.
Explain the reabsorptive process of sperm in the male reproductive system.
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List key aspects of equine body language and behavior that should be used to assess safety implications for handlers.
List key aspects of equine body language and behavior that should be used to assess safety implications for handlers.
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Outline the legislation that places a duty of care on those responsible for horses in the UK.
Outline the legislation that places a duty of care on those responsible for horses in the UK.
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Discuss the absorptive and secretory functions of the accessory sex glands in the male reproductive system.
Discuss the absorptive and secretory functions of the accessory sex glands in the male reproductive system.
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What are some major welfare issues facing horses in the UK?
What are some major welfare issues facing horses in the UK?
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Outline the tests that can be performed to identify a 'rig' in horses.
Outline the tests that can be performed to identify a 'rig' in horses.
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Explain the legal requirements for identification of horses by microchip and passport.
Explain the legal requirements for identification of horses by microchip and passport.
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What factors contribute to the variation in the cost of castration for horses?
What factors contribute to the variation in the cost of castration for horses?
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What are the costs involved in castration and where are they incurred?
What are the costs involved in castration and where are they incurred?
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What should be included in the cost of castration for horses under general anaesthetic?
What should be included in the cost of castration for horses under general anaesthetic?
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What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
What is the purpose of testing for Oestrone Sulphate in horses suspected to be 'rigs'?
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What is the legal duty of those who own or are responsible for a horse under the Animal Welfare Act (2013)?
What is the legal duty of those who own or are responsible for a horse under the Animal Welfare Act (2013)?
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What is the role of hypothalamus in regulating male reproduction?
What is the role of hypothalamus in regulating male reproduction?
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Foals should have a valid passport and microchip before they reach ______ old, according to legal requirements.
Foals should have a valid passport and microchip before they reach ______ old, according to legal requirements.
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Study Notes
Estimating Horse Weight
- Use a horse weight tape to calculate approximate weights for horses
- Stand the horse square on a flat surface, placing the 'zero' end of the tape at the lowest point of the horse's withers
- Bring the tape around the horse's girth, passing behind the elbows, and pull it up to meet the 'zero' for the approximate weight
Scrotal Location of Testes and Temperature Dependence
- Testes are stored in the scrotum outside of the body cavity, allowing for a lower temperature and enabling spermatogenesis
- Spermatogenesis is highly temperature dependent and ceases to function above 35°C in most domestic species
Descent of Testes
- Initial intra-abdominal position: Testicles develop retroperitoneally near the kidneys and dorsal body wall
- Descent process:
- Transabdominal phase: Cranial gonadal ligament degenerates, and the testis begins to descend towards the scrotum
- Inguinoscrotal phase: Testes pass through the inguinal canal to reach the scrotum, regulated by androgens and the genitofemoral nerve
- Abnormalities in the descent process can result in cryptorchidism
- Undescended testis (UDT) can be located in the abdominal cavity or inguinal canal
Internal and External Inguinal Rings
- Inguinal canal formed by two gaps: internal and external rings
- Internal ring: formed of transversalis fascia, located above the midpoint of the inguinal ligament
- External ring: formed by fibres of the external abdominal oblique muscle, located at the terminal end of the inguinal canal
Extra-Testicular Androgen Receptors
- Androgen receptors (AR) located on the X chromosome, expressed in various tissues
- Main locations: testicular, epididymal, and accessory sex glands
- Specific receptors in sertoli cells, myoid cells, and cells in the interstitial spaces
Hypothalamus and Male Reproduction
- Hypothalamus regulates male reproduction by regulating the activity of the pituitary gland and releasing hormones
- Pulsatile secretion of gonadotropin releasing hormone (GnRH) stimulates the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
- LH stimulates Leydig cells to produce androgens, predominantly testosterone, for male development
Effects of Androgens on Male Behaviour and Appearance
- Androgens have masculinising effects on the male reproductive system
- Androgen effects on cells:
- Leydig cells: autocrine effect on cells in a short negative feedback loop
- Myoid cells: maintains functional integrity and contractility of the seminiferous tubules
- Sertoli cells: testosterone is converted to DHT (more biologically active), vital for maintaining spermatogenesis
- Androgen activational effects: maintenance of spermatogenesis, erectile capacity, and secondary sexual characteristics
Sperm Transport in the Male Reproductive Tract
- Spermatogenesis occurs in seminiferous tubules
- Spermatozoa collected into rete testis
- Efferent ducts reabsorb fluid and concentrate sperm
- Epididymis: mature and store sperm
- Deferent duct: transports sperm to pelvic urethra at ejaculation
Absorptive and Secretory Functions of the Male Reproductive Tract
- Reabsorption of sperm occurs in two steps: macrophages break down old or unused sperm, and remnants are absorbed into the membrane lining the epididymis
- Accessory sex glands produce seminal fluid to aid motility and nourish sperm
Penile Erection
- Sympathetic nerves cause tonic contractions of the smooth muscle walls of the erectile tissue
- Parasympathetic control is up-regulated during erection, smooth muscle relaxes, and space fills with blood
- Muscles in the urogenital diaphragm compress veins, causing blood to become trapped in the cavernous spaces
Behavioural Changes Associated with Castration
- After castration, testosterone levels decrease, and aggression towards other horses and humans may decrease
- However, some geldings may still display masculine behaviour and aggression
Legislation and Duty of Care
- Legislation in the UK places a duty of care on those responsible for horses
- Handlers must ensure the health and safety of both the horse and themselves
Health and Safety Risks
- Handling aggressive or unhandled horses can lead to physical injuries, attempts to escape, and unpredictable reactions
- Safe handling involves careful assessment of body language, appropriate use of physical restraint, and consideration of licenced drugs for sedation### Prenatal Development
- Prenatal androgens masculinize the hypothalamus, preventing positive feedback of LH characteristic of female ovarian cyclicity.
- Testosterone production masculinizes the external genitalia, developing the penis and scrotum.
Sperm Transport
- Spermatogenesis occurs in seminiferous tubules.
- Spermatozoa collect in the rete testis.
- Efferent ducts reabsorb and concentrate fluid.
- Epididymis matures and stores sperm.
- Deferent duct transports sperm to the pelvic urethra at ejaculation.
Absorptive and Secretory Functions
- Reabsorption of sperm occurs in two steps: breakdown by macrophages and absorption into the epididymis membrane.
- Accessory sex glands (ampulla gland, vesicular glands, prostate gland, and bulbourethral glands) produce seminal fluid for sperm motility and nourishment.
Physiological Mechanisms of Penile Erection
- Sympathetic nerves cause tonic contractions of smooth muscle walls in erectile tissue.
- Parasympathetic control relaxes smooth muscle, allowing blood to fill the space.
- Muscles in the urogenital diaphragm compress veins, trapping blood and causing erection.
Castration in Horses
- Castration decreases testosterone levels, reducing aggression and stallion-like behavior.
- Some geldings (20-30%) may still display masculine behavior and aggression.
- Castration does not guarantee elimination of stallion-like behavior.
Reasons for Castration
- Undesirable genetic traits
- Behavioral issues (aggression, difficulty in training) caused by high testosterone
- Cryptorchidism (undescended testicles) leading to undesirable traits and lower sperm count
Equine Body Language and Behavior
- Stance, ears, eyes, muzzle, nostrils, and mouth can indicate a horse's emotional state.
- Spending time with a horse helps recognize normal behavior and potential safety implications.
Health and Safety Risks
- Handling unhandled horses poses physical injury risks to handlers (bites, kicks, strikes).
- Correct interactions, careful assessment of body language, and appropriate physical restraint can minimize risks.
Legislation
- UK legislation places a duty of care on those responsible for horses.
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Description
This quiz covers the mechanisms for sperm transport in the male reproductive tract, including spermatogenesis in the seminiferous tubules, collection of spermatozoa into rete testis, and fluid reabsorption by efferent ducts. Test your knowledge on the processes involved in male reproductive system function.