Malaria Symptoms and Pathophysiology

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23 Questions

Which species of Plasmodium is the most pathogenic?

P.falciparum

Which age group is most affected by malaria?

Children under 5

In which host does the sexual development (sporogony) of malaria parasites occur?

Female Anopheles mosquito

Which type of schizogony occurs in man (intermediate host)?

Primary exo-erythrocytic schizogony

Which Plasmodium species causes malaria with a relapse every 72 hours?

P. malariae

What type of schizogony involves P. vivax and P. ovale persisting as hypnozoites?

Secondary exo-erythrocytic

Which Plasmodium species can cause periodic relapses for up to 5 years without treatment?

P. vivax

In the mosquito cycle, what process involves the formation of microgametes from microgametocytes?

Exflagellation

Which Plasmodium species has large rings in the trophozoite stage that may adhere to red cells?

P. vivax

What is the characteristic pigment color found in developing trophozoites of P. falciparum?

Black; few clumps

How many merozoites are usually found in mature schizonts of P. malariae?

<12 merozoites

What type of red blood cells do vivax merozoites invade?

Immature red blood cells (reticulocytes)

Where do P.vivax hypnozoites lie dormant?

In the liver

Which medication is typically used to treat malarial attacks caused by P.vivax?

Chloroquine and amodiaquine

When do gametocytes typically appear in relation to asexual parasites?

Before the onset of symptoms

How are antimosquito chemicals like DDT and Malathion helpful in controlling malaria?

Prevent the transmission of malaria by killing mosquitoes

Which of the following is not mentioned as a method for malaria control in the text?

Consuming garlic daily

What is the main cause of anemia in malaria patients?

Destruction of RBCs by parasite and lysis of non-parasitized cells

Which parasite infects the youngest erythrocytes?

P. vivax

What causes blockage of blood capillaries in vital areas like the brain, lung, and kidney in malaria?

Adhesion of infected erythrocytes to blood vessel linings

Which type of malaria is characterized by a lack of synchronized asexual cycles leading to atypical fever patterns?

P. falciparum

How does spleen enlargement occur in malaria?

Massive proliferation of macrophages phagocytosing RBCs

Which type of malaria can lead to life-threatening complications known as pernicious malaria?

P. falciparum

Explore the signs and symptoms, as well as the pathophysiology of malaria, particularly focusing on the destruction of red blood cells by the parasite. Learn how the quantity of pyrogen produced leads to characteristic chills and fever in severe cases.

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