18 Questions
Which type of gametes unite to form the zygote in the vector host?
Microgamete and macrogamete
What is the first stage of the life cycle of malaria parasite in the human host?
Sporozoite development
What initiates the inoculation of sporozoites into the bloodstream of a human victim by an infected female Anopheles mosquito?
Taking a blood meal
Which of the following factors influence the effectiveness of an Anopheles mosquito in transmitting malaria?
Survival for sporozoite development
What is the final stage in the process of sporozoites developing in the vertebrate host?
Schizogony
In what form are sporozoites introduced into the vertebrate host by the Anopheles mosquito?
Spindle-shaped bodies
What was the original belief regarding relapse in malaria?
It was caused by parasites remaining in the exoerythrocytic cycle known as para-erythrocytic cycle.
What is the distinguishing feature of long prepatent sporozoites (LPPs) or hypnozoites compared to short prepatent sporozoites (SPPs)?
They remain dormant in hepatocytes for an indefinite period.
What triggers the activation of hypnozoites leading to malaria relapse?
Stimulus like physiological fluctuations.
Which species of Plasmodium is identified as the most virulent and responsible for the highest mortality in human malaria?
Plasmodium falciparum
What are some initial symptoms of malaria that are often mistaken for other common illnesses?
Nausea and fatigue
How does relapse occur in malaria infections involving hypnozoites?
Through activation of dormant hypnozoites.
What is the name of the reddish dots that appear in P.falciparum infected R.B.Cs.?
Maurer’s dots
How long does it take for merozoites to spend a regular period in P.ovale?
48 hours
What process do microgametocytes undergo in the mosquito's stomach?
Exflagellation
What is the distinctive feature of Ziemann’s dots in P.malariae infected R.B.Cs.?
They are less in number
In which type of malaria parasite does the infected person feel chills, fever, and sweating sequentially?
P.falciparum
What happens to the ripe gametocytes ingested by female Anopheles mosquitoes during a blood meal?
They transform into mature gametes
Test your knowledge on the complex life cycle of malaria parasites, including the exoerythrocytic and erythrocytic phases. Learn about how relapse in malaria was previously believed to be due to para-erythrocytic cycles within the liver.
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