Maalox Drug Flashcards

Drug Overview

• Maalox belongs to the antacid drug group, commonly used to neutralize stomach acid.

Composition

• Active ingredients include Aluminium hydroxide (Al(OH)3) and Magnesium hydroxide (Mg(OH)2).

Legal Status

• Classified as General Sale List (GSL), meaning it can be sold without a prescription.

Formulation Type

• Available in oral suspension form, facilitating ease of administration.

Indications for Use

• Primarily indicated for treating dyspepsia; usage is not recommended for individuals under 14 years.
• May also be utilized to alleviate constipation.

Mechanism of Action

• Neutralizes stomach acid by hydroxide ions reacting with hydrogen ions from parietal cells, forming magnesium and water.
• Increases pH, inhibiting pepsin action; may have cytoprotective effects through enhanced bicarbonate and prostaglandins.
• Acts as a laxative by drawing water into the intestines, softening stools, and increasing fecal volume.

Dosage Guidelines

• Recommended adult dose is 10-20 ml, taken 20-60 minutes after meals or at bedtime, as needed.

Effectiveness Monitoring

• Relief of symptoms such as retrosternal pain, acid reflux, and flatulence indicates efficacy; if symptoms persist, refer to a GP for further assessment.

Common Side Effects

• Possible side effects include diarrhea, constipation, and electrolyte imbalances.

Side Effect Monitoring

• Monitor for elevated blood pressure due to salt formation; halt treatment and seek advice from a pharmacist or GP if severe diarrhea occurs.

Drug Interactions

• Aluminium hydroxide may reduce absorption of chenodeoxycholic acid and iron chelators.
• Magnesium hydroxide can decrease the absorption of clodronate and risedronate.

Patient Information

• Do not administer to children under 14 years.
• Advise patients with high blood pressure to consult a doctor.
• For those taking chenodeoxycholic acid, separate dosing by 5 hours to avoid interaction.