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Questions and Answers
What is physiology?
What is physiology?
The science that seeks to explain the physical and chemical mechanisms responsible for the origin, development, and progression of life.
What percentage of the adult human body is fluid?
What percentage of the adult human body is fluid?
About 60 percent.
What is the main component of intracellular fluid (ICF)?
What is the main component of intracellular fluid (ICF)?
Homeostasis is the body's ability to maintain a stable internal environment.
Homeostasis is the body's ability to maintain a stable internal environment.
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What is the basic living unit of the body?
What is the basic living unit of the body?
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What is the extracellular fluid (ECF) responsible for?
What is the extracellular fluid (ECF) responsible for?
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What do powerful control systems in the body maintain?
What do powerful control systems in the body maintain?
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Disease is often considered a state of disrupted homeostasis.
Disease is often considered a state of disrupted homeostasis.
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Study Notes
Physiology and Human Physiology
- Physiology studies the physical and chemical mechanisms responsible for life's origin, development, and progression.
- Human physiology focuses on the specific characteristics and mechanisms that make the human body alive.
- The human body has complex control systems responsible for its survival. For example, hunger prompts us to seek food, and cold sensations cause us to search for warmth.
Cells
- Cells are the basic living units of the body.
- Each organ is composed of various cells held together by intercellular supporting structures.
- Different cell types are specialized to perform specific functions.
- The human body contains approximately 100 trillion cells.
- Although many cells differ significantly, they share basic characteristics:
- Oxygen reacts with carbohydrates, fats, and proteins to release energy for cell function.
- The chemical mechanisms for converting nutrients into energy are similar across cells.
- Cells release byproducts of chemical reactions into surrounding fluids.
- Most cells can reproduce to replace damaged cells.
Body Fluids
- About 60% of the adult human body is fluid, primarily a water solution of ions and other substances.
- Intracellular fluid (ICF) is the fluid inside cells, while extracellular fluid (ECF) is the fluid outside cells, representing about one-third of the total body fluid.
- ECF is constantly circulating throughout the body, carried by blood and diffusing between blood and tissue fluids through capillary walls.
- ECF provides cells with necessary ions and nutrients like oxygen, glucose, amino acids, and fatty acids.
- ECF also carries carbon dioxide from cells to the lungs for excretion and other cellular waste products to the kidneys for excretion.
- ICF differs significantly from ECF, containing high levels of potassium, magnesium, and phosphate ions instead of sodium and chloride ions.
- Mechanisms for transporting ions across cell membranes maintain the ion differences between ECF and ICF.
Homeostasis (Steady State)
- Homeostasis refers to the body's ability to maintain a stable internal environment by regulating factors like hormones, body temperature, water balance, and more.
- All organs and tissues contribute to maintaining these stable internal conditions.
- For instance, the lungs provide oxygen to the ECF, the kidneys control ion concentrations, and the gastrointestinal system supplies nutrients.
- Powerful control systems maintain the proper concentrations of ions, nutrients, and substances within the body, despite external variations and challenges from injuries or diseases.
- Homeostasis relies on the integrated actions of cells, tissues, organs, and nervous, hormonal, and local control systems.
- Diseases are often considered a disruption of homeostasis.
Homeostasis - Maintaining a Stable Environment
- Maintaining homeostasis requires continuous monitoring of internal conditions.
- Physiological parameters like body temperature and blood pressure fluctuate within a specific normal range, often referred to as set points.
- Homeostasis is essential for the body to function correctly and operate optimally.
- The body employs various mechanisms to maintain homeostasis, including feedback loops, which either amplify or dampen a stimulus.
- An example is the thermoregulation system, which maintains body temperature by regulating heat production and loss.
- Feedback loops constantly adjust physiological parameters, ensuring they remain within the optimal range for proper function.
Homeostasis and Disease
- Homeostasis, a state of stable internal environment, is crucial for good health and proper functioning of the body.
- Disruption of homeostasis often disrupts physiological processes and can lead to disease.
- Examples of homeostatic imbalances include:
- Diabetes: The body cannot regulate blood glucose levels correctly.
- Hypertension: Elevated blood pressure affects heart function and blood flow.
- Anemia: Inadequate oxygen delivery due to low red blood cell count.
- Maintaining homeostasis is essential, and disease conditions frequently involve a disturbance in homeostatic processes.
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