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Lymphoid Neoplasm

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Questions and Answers

What is the age group with the highest frequency of ALL?

Children under 10 years old
Children at the age of 34 years (correct)
Elderly people above 65 years old
Adults between 30-40 years old

What is a risk factor for developing secondary ALL?

Infection with a specific virus
Poor diet and lack of exercise
Cytostatic treatment with alkylating agents (correct)
Family history of ALL

What percentage of ALL patients have a WBC above 100 x 10^5/L?

8%
16% (correct)
80%
40%

What percentage of ALL patients have no circulating leukemic blasts?

8% (C) Signup and view all the answers

What is a common genetic abnormality found in elderly B-lineage ALL patients?

Philadelphia chromosome-positive (C) Signup and view all the answers

What is the incidence rate of ALL in adults per 100,000 per year?

0.7-1.8 (D) Signup and view all the answers

In acute lymphoid leukemia, which of the following subtype is observed in 25% of adult ALLs?

T-Cell Lineage ALL (C) Signup and view all the answers

What is the significance of MRD in acute lymphoid leukemia?

It is the most important prognostic factor during therapy (B) Signup and view all the answers

In chronic lymphocytic leukemia, what is the most robust prognostic factor?

Immunoglobulin heavy chain (IGHV) mutational status (B) Signup and view all the answers

What is the recommended duration of maintenance therapy for T-ALL and B-ALL?

2-2.5 years (D) Signup and view all the answers

What is the significance of Richter’s transformation in CLL?

It is a transformation of CLL to aggressive lymphoma (D) Signup and view all the answers

What is the primary goal of induction therapy in acute lymphoid leukemia?

Achievement of a clinical CR (C) Signup and view all the answers

In Hodgkin lymphoma, what is the role of EBV in HIV-related cHL?

EBV is detected in nearly all HIV-associated cHL cases (D) Signup and view all the answers

In non-Hodgkin lymphoma, what is the most common type of NHL in adults?

Diffuse large B cell lymphoma (A) Signup and view all the answers

What is the significance of PET/CT scan in Hodgkin lymphoma?

It is used to monitor treatment response (D) Signup and view all the answers

In chronic lymphocytic leukemia, what is the significance of del(13)(q14.3)?

Indicates a more indolent disease (D) Signup and view all the answers