16 Questions
What is the age group with the highest frequency of ALL?
Children at the age of 34 years
What is a risk factor for developing secondary ALL?
Cytostatic treatment with alkylating agents
What percentage of ALL patients have a WBC above 100 x 10^5/L?
16%
What percentage of ALL patients have no circulating leukemic blasts?
8%
What is a common genetic abnormality found in elderly B-lineage ALL patients?
Philadelphia chromosome-positive
What is the incidence rate of ALL in adults per 100,000 per year?
0.7-1.8
In acute lymphoid leukemia, which of the following subtype is observed in 25% of adult ALLs?
T-Cell Lineage ALL
What is the significance of MRD in acute lymphoid leukemia?
It is the most important prognostic factor during therapy
In chronic lymphocytic leukemia, what is the most robust prognostic factor?
Immunoglobulin heavy chain (IGHV) mutational status
What is the recommended duration of maintenance therapy for T-ALL and B-ALL?
2-2.5 years
What is the significance of Richter’s transformation in CLL?
It is a transformation of CLL to aggressive lymphoma
What is the primary goal of induction therapy in acute lymphoid leukemia?
Achievement of a clinical CR
In Hodgkin lymphoma, what is the role of EBV in HIV-related cHL?
EBV is detected in nearly all HIV-associated cHL cases
In non-Hodgkin lymphoma, what is the most common type of NHL in adults?
Diffuse large B cell lymphoma
What is the significance of PET/CT scan in Hodgkin lymphoma?
It is used to monitor treatment response
In chronic lymphocytic leukemia, what is the significance of del(13)(q14.3)?
Indicates a more indolent disease
This quiz covers various types of lymphoid neoplasms, including acute lymphoblastic leukemia, chronic lymphocytic leukemia, Hodgkin lymphoma, and non-Hodgkin lymphoma. It also discusses the characteristics and epidemiology of these diseases. Test your knowledge of lymphoid neoplasms!
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