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Lymphoid Neoplasm

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Questions and Answers

What is the age group with the highest frequency of ALL?

Children under 10 years old

Children at the age of 34 years (correct)

Elderly people above 65 years old

Adults between 30-40 years old

What is a risk factor for developing secondary ALL?

Infection with a specific virus

Poor diet and lack of exercise

Cytostatic treatment with alkylating agents (correct)

Family history of ALL

What percentage of ALL patients have a WBC above 100 x 10^5/L?

16% (correct)

80%

40%

What percentage of ALL patients have no circulating leukemic blasts?

8% Signup and view all the answers

What is a common genetic abnormality found in elderly B-lineage ALL patients?

Philadelphia chromosome-positive Signup and view all the answers

What is the incidence rate of ALL in adults per 100,000 per year?

0.7-1.8 Signup and view all the answers

In acute lymphoid leukemia, which of the following subtype is observed in 25% of adult ALLs?

T-Cell Lineage ALL Signup and view all the answers

What is the significance of MRD in acute lymphoid leukemia?

It is the most important prognostic factor during therapy Signup and view all the answers

In chronic lymphocytic leukemia, what is the most robust prognostic factor?

Immunoglobulin heavy chain (IGHV) mutational status Signup and view all the answers

What is the recommended duration of maintenance therapy for T-ALL and B-ALL?

2-2.5 years Signup and view all the answers

What is the significance of Richter’s transformation in CLL?

It is a transformation of CLL to aggressive lymphoma Signup and view all the answers

What is the primary goal of induction therapy in acute lymphoid leukemia?

Achievement of a clinical CR Signup and view all the answers

In Hodgkin lymphoma, what is the role of EBV in HIV-related cHL?

EBV is detected in nearly all HIV-associated cHL cases Signup and view all the answers

Lymphoid Neoplasm

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Podcast

Questions and Answers

What is the age group with the highest frequency of ALL?

What is a risk factor for developing secondary ALL?

What percentage of ALL patients have a WBC above 100 x 10^5/L?

What percentage of ALL patients have no circulating leukemic blasts?

What is a common genetic abnormality found in elderly B-lineage ALL patients?

What is the incidence rate of ALL in adults per 100,000 per year?

In acute lymphoid leukemia, which of the following subtype is observed in 25% of adult ALLs?

What is the significance of MRD in acute lymphoid leukemia?

In chronic lymphocytic leukemia, what is the most robust prognostic factor?

What is the recommended duration of maintenance therapy for T-ALL and B-ALL?

What is the significance of Richter’s transformation in CLL?

What is the primary goal of induction therapy in acute lymphoid leukemia?

In Hodgkin lymphoma, what is the role of EBV in HIV-related cHL?

In non-Hodgkin lymphoma, what is the most common type of NHL in adults?

What is the significance of PET/CT scan in Hodgkin lymphoma?

In chronic lymphocytic leukemia, what is the significance of del(13)(q14.3)?

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