Podcast
Questions and Answers
Which of the following statements correctly describes the function of lymphatic vessels?
Which of the following statements correctly describes the function of lymphatic vessels?
- They facilitate the exchange of nutrients between tissues and blood.
- They carry excess extracellular fluid back to the venous system. (correct)
- They act as valves to maintain pressure in the arterial system.
- They primarily transport oxygenated blood throughout the body.
What is the primary reason for the opaque and milky appearance of chyle in the lymphatic vessels?
What is the primary reason for the opaque and milky appearance of chyle in the lymphatic vessels?
- It is a result of fluid contamination with tissue debris.
- It contains high levels of extracellular enzymes.
- It contains high concentrations of immune cells.
- It is enriched with chylomicrons resulting from fat absorption. (correct)
In which of the following areas are lymphatic vessels absent?
In which of the following areas are lymphatic vessels absent?
- The brain and bone marrow (correct)
- Muscles and skin
- The liver and spleen
- Kidneys and lungs
What is the function of valves in lymphatic vessels?
What is the function of valves in lymphatic vessels?
Which lymphatic duct is responsible for draining lymph from the left side of the body?
Which lymphatic duct is responsible for draining lymph from the left side of the body?
What is the primary role of the thymus in the immune system?
What is the primary role of the thymus in the immune system?
Which statement accurately describes the structure of lymphoid organs?
Which statement accurately describes the structure of lymphoid organs?
What happens to the thymus after puberty?
What happens to the thymus after puberty?
Which cells are primarily responsible for supporting the developing T cells in the thymus?
Which cells are primarily responsible for supporting the developing T cells in the thymus?
Which function is NOT associated with the thymic cortex?
Which function is NOT associated with the thymic cortex?
Flashcards
Lymphatic System
Lymphatic System
A network of vessels responsible for collecting excess fluid from tissues and returning it to the bloodstream.
Lymph Nodes
Lymph Nodes
Small, bean-shaped organs that filter lymph fluid and house immune cells.
Thoracic Duct
Thoracic Duct
The primary lymphatic duct, collecting lymph from most of the body.
Lymph
Lymph
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Chyle
Chyle
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What is the thymus and its role in the immune system?
What is the thymus and its role in the immune system?
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What happens to the thymus after puberty?
What happens to the thymus after puberty?
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Describe the structure of the thymus.
Describe the structure of the thymus.
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What is the role of epithelial reticular cells in the thymus?
What is the role of epithelial reticular cells in the thymus?
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Define immunological competency and explain its significance in the thymus.
Define immunological competency and explain its significance in the thymus.
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Study Notes
Lymphatic System
- The lymphatic system returns excess extracellular fluid to the venous system
- Lymph is a clear, colorless fluid that contains pathogens, cellular debris, hormones
- Chyle is opaque, milky lymph from the small intestine due to chylomicrons
- Lymphatic vessels are absent in the brain, bone marrow and avascular tissues (epithelia, cartilage)
- Lymphatic vessels have valves which maintain unidirectional flow
Lymphatic Structures
- Lymphatic system consists of: Lymph nodes, lymphatic vessels, lymphatic ducts
- Lymphatic vessels form a network, beginning as lymphatic capillaries that converge into larger vessels
- Two lymphatic ducts: Thoracic duct (drains all but upper right quadrant) and right lymphatic duct (drains upper right quadrant)
Specialized Immune Tissues
- Lymphoid organs (e.g. thymus, lymph nodes) have two parts:
- Stroma: supporting connective tissue framework (capsule and trabeculae, fine reticular fibers)
- Parenchyma: functional cellular part (cortex, medulla)
- The thymus: primary lymphoid organ where T lymphocytes mature
- Involuted (shrinks) after puberty
- Composed of cortex and medulla
- Hassall's corpuscles (composed of epithelial cells) in the medulla
- Forms blood thymus barrier that prevents immature T-cells from contacting foreign antigens
Lymph Nodes
- Oval, encapsulated structures along lymphatic vessels
- Afferent vessels bring lymph in
- Efferent vessels carry lymph out through the hilum (concave side)
- Divided into three regions: cortex (containing B-cell nodules), paracortex (T cells), medulla (plasma cells)
- Lymph filtration and antigen presentation occur
- Secondary lymphatic nodules: germinal centers (proliferation of activated B cells)
- Lymph nodes are frequently sites of infections and tumors
Clinical Correlations
- Lymphangitis: inflamed lymphatic vessels
- Lymphadenitis: inflamed lymph nodes
- Lymphedema: impaired lymph drainage leading to swelling
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