Lymphatic System Quiz

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Questions and Answers

Which of the following statements correctly describes the function of lymphatic vessels?

  • They facilitate the exchange of nutrients between tissues and blood.
  • They carry excess extracellular fluid back to the venous system. (correct)
  • They act as valves to maintain pressure in the arterial system.
  • They primarily transport oxygenated blood throughout the body.

What is the primary reason for the opaque and milky appearance of chyle in the lymphatic vessels?

  • It is a result of fluid contamination with tissue debris.
  • It contains high levels of extracellular enzymes.
  • It contains high concentrations of immune cells.
  • It is enriched with chylomicrons resulting from fat absorption. (correct)

In which of the following areas are lymphatic vessels absent?

  • The brain and bone marrow (correct)
  • Muscles and skin
  • The liver and spleen
  • Kidneys and lungs

What is the function of valves in lymphatic vessels?

<p>To ensure unidirectional flow of lymph. (D)</p> Signup and view all the answers

Which lymphatic duct is responsible for draining lymph from the left side of the body?

<p>Thoracic duct (A)</p> Signup and view all the answers

What is the primary role of the thymus in the immune system?

<p>Maturation of T lymphocytes (C)</p> Signup and view all the answers

Which statement accurately describes the structure of lymphoid organs?

<p>The stroma includes a capsule and trabeculae for support. (A)</p> Signup and view all the answers

What happens to the thymus after puberty?

<p>It begins to involute and becomes infiltrated by adipose cells. (B)</p> Signup and view all the answers

Which cells are primarily responsible for supporting the developing T cells in the thymus?

<p>Epithelial reticular cells (D)</p> Signup and view all the answers

Which function is NOT associated with the thymic cortex?

<p>Antibody production by B cells (A)</p> Signup and view all the answers

Flashcards

Lymphatic System

A network of vessels responsible for collecting excess fluid from tissues and returning it to the bloodstream.

Lymph Nodes

Small, bean-shaped organs that filter lymph fluid and house immune cells.

Thoracic Duct

The primary lymphatic duct, collecting lymph from most of the body.

Lymph

Fluid collected from tissues by the lymphatic system, containing immune cells and waste products.

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Chyle

The milky lymph from the small intestine, rich in fats and chylomicrons.

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What is the thymus and its role in the immune system?

The thymus is a primary lymphoid organ responsible for the maturation of T lymphocytes, crucial for the immune system's ability to recognize and fight off foreign invaders.

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What happens to the thymus after puberty?

The thymus undergoes involution, a process of gradual shrinkage and replacement by fat cells, after puberty. However, it can still function in older adults.

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Describe the structure of the thymus.

The thymus is divided into lobules, each containing a cortex and a medulla. The cortex is denser and houses immature T lymphocytes undergoing maturation, while the medulla holds mature T cells.

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What is the role of epithelial reticular cells in the thymus?

Epithelial reticular cells form a network within the thymus, providing structural support and guidance for developing T lymphocytes. This network is known as cytoreticulum.

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Define immunological competency and explain its significance in the thymus.

Immunological competency refers to the ability of T lymphocytes to recognize and respond to specific antigens. This process occurs in the thymic cortex, where self-intolerant T cells are also eliminated to prevent autoimmune reactions.

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Study Notes

Lymphatic System

  • The lymphatic system returns excess extracellular fluid to the venous system
  • Lymph is a clear, colorless fluid that contains pathogens, cellular debris, hormones
  • Chyle is opaque, milky lymph from the small intestine due to chylomicrons
  • Lymphatic vessels are absent in the brain, bone marrow and avascular tissues (epithelia, cartilage)
  • Lymphatic vessels have valves which maintain unidirectional flow

Lymphatic Structures

  • Lymphatic system consists of: Lymph nodes, lymphatic vessels, lymphatic ducts
  • Lymphatic vessels form a network, beginning as lymphatic capillaries that converge into larger vessels
  • Two lymphatic ducts: Thoracic duct (drains all but upper right quadrant) and right lymphatic duct (drains upper right quadrant)

Specialized Immune Tissues

  • Lymphoid organs (e.g. thymus, lymph nodes) have two parts:
    • Stroma: supporting connective tissue framework (capsule and trabeculae, fine reticular fibers)
    • Parenchyma: functional cellular part (cortex, medulla)
  • The thymus: primary lymphoid organ where T lymphocytes mature
    • Involuted (shrinks) after puberty
    • Composed of cortex and medulla
    • Hassall's corpuscles (composed of epithelial cells) in the medulla
    • Forms blood thymus barrier that prevents immature T-cells from contacting foreign antigens

Lymph Nodes

  • Oval, encapsulated structures along lymphatic vessels
  • Afferent vessels bring lymph in
  • Efferent vessels carry lymph out through the hilum (concave side)
  • Divided into three regions: cortex (containing B-cell nodules), paracortex (T cells), medulla (plasma cells)
  • Lymph filtration and antigen presentation occur
  • Secondary lymphatic nodules: germinal centers (proliferation of activated B cells)
  • Lymph nodes are frequently sites of infections and tumors

Clinical Correlations

  • Lymphangitis: inflamed lymphatic vessels
  • Lymphadenitis: inflamed lymph nodes
  • Lymphedema: impaired lymph drainage leading to swelling

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