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Questions and Answers
Which tissue type is characterized by a specialized form of reticular connective tissue abundant in lymphocytes?
Which tissue type is characterized by a specialized form of reticular connective tissue abundant in lymphocytes?
- Reticular Epithelium
- Reticular Tissue
- Lymphatic Tissue (correct)
- Immune Tissue
What structural feature primarily distinguishes lymphatic capillaries from blood capillaries?
What structural feature primarily distinguishes lymphatic capillaries from blood capillaries?
- Lymphatic capillaries have greater permeability than blood capillaries (correct)
- Lymphatic vessels have thicker walls than veins
- Veins have one-way valves that prevent blood from escaping
- There is no structural difference
Which pairing of lymph duct and drainage region is mismatched?
Which pairing of lymph duct and drainage region is mismatched?
- Right lymphatic duct—right side of body inferior to the ribs (correct)
- Right lymphatic duct—right jugular veins
- Thoracic duct—the entire body inferior to the ribs
- Thoracic duct—left jugular veins
The thoracic duct originates as the cisterna chyli, which receives lymph from which trunks?
The thoracic duct originates as the cisterna chyli, which receives lymph from which trunks?
What sequence accurately describes the flow of fluid from blood capillaries back to the bloodstream via the lymphatic system?
What sequence accurately describes the flow of fluid from blood capillaries back to the bloodstream via the lymphatic system?
What is the primary immunological role of the thymus?
What is the primary immunological role of the thymus?
What age-related change occurs in the thymus?
What age-related change occurs in the thymus?
In what sequence does lymph flow through a lymph node?
In what sequence does lymph flow through a lymph node?
What is the fate of foreign substances that enter a lymph node within the lymph?
What is the fate of foreign substances that enter a lymph node within the lymph?
The innate immune system involves several components, EXCEPT which of the following?
The innate immune system involves several components, EXCEPT which of the following?
Which of the following is NOT an internal defense protecting against microbes that penetrate the skin and mucous membranes?
Which of the following is NOT an internal defense protecting against microbes that penetrate the skin and mucous membranes?
What are antimicrobial proteins that primarily target viral replication called?
What are antimicrobial proteins that primarily target viral replication called?
Which type of leukocyte is classified as a natural killer cell?
Which type of leukocyte is classified as a natural killer cell?
What is the correct sequence of events in phagocytosis?
What is the correct sequence of events in phagocytosis?
How are microbes destroyed after being ingested by a phagocyte?
How are microbes destroyed after being ingested by a phagocyte?
Where are complement proteins primarily produced?
Where are complement proteins primarily produced?
Which mechanism is NOT a part of the complement system's action against microbes?
Which mechanism is NOT a part of the complement system's action against microbes?
How is the complement system typically activated?
How is the complement system typically activated?
What does it mean when a cell is described as 'immunocompetent'?
What does it mean when a cell is described as 'immunocompetent'?
Where do T cells and B cells undergo development?
Where do T cells and B cells undergo development?
Which outcome is NOT a function of adaptive immunity?
Which outcome is NOT a function of adaptive immunity?
What process involves breaking down antigenic proteins into peptide fragments that form antigen-MHC molecules, followed by the insertion of the antigen-MHC complex into the plasma membrane?
What process involves breaking down antigenic proteins into peptide fragments that form antigen-MHC molecules, followed by the insertion of the antigen-MHC complex into the plasma membrane?
What is the primary role of major histocompatibility complex (MHC) molecules?
What is the primary role of major histocompatibility complex (MHC) molecules?
Which of the following is not considered an example of endogenous antigens?
Which of the following is not considered an example of endogenous antigens?
Which statement accurately describes the initial step in the activation of a T cell?
Which statement accurately describes the initial step in the activation of a T cell?
Which type of active T cells directly attack other body cells that have been infected with an antigen?
Which type of active T cells directly attack other body cells that have been infected with an antigen?
Besides cells infected by microbes, what other types of cells do cytotoxic T cells target?
Besides cells infected by microbes, what other types of cells do cytotoxic T cells target?
How do cytotoxic T cells induce cell death in infected target cells?
How do cytotoxic T cells induce cell death in infected target cells?
Which type of T cell participates in both cell-mediated and antibody-mediated immune responses?
Which type of T cell participates in both cell-mediated and antibody-mediated immune responses?
With what specific part of the antigen does an antibody combine?
With what specific part of the antigen does an antibody combine?
In what aspects do the five classes of antibodies differ?
In what aspects do the five classes of antibodies differ?
Through which mechanism do antibodies NOT disable antigens?
Through which mechanism do antibodies NOT disable antigens?
What type of cell is described as a 'descendant of a B cell that remains after an immune response and is ready to respond rapidly and forcefully should the same antigen enter the body in the future'?
What type of cell is described as a 'descendant of a B cell that remains after an immune response and is ready to respond rapidly and forcefully should the same antigen enter the body in the future'?
How does the secondary response to an antigen typically differ from the primary response?
How does the secondary response to an antigen typically differ from the primary response?
Which antibody type is predominantly involved in the secondary response?
Which antibody type is predominantly involved in the secondary response?
Which complement protein is NOT directly involved in the formation of the membrane attack complex (MAC)?
Which complement protein is NOT directly involved in the formation of the membrane attack complex (MAC)?
Which substance is NOT released by cytotoxic T cells to induce cell death in target cells?
Which substance is NOT released by cytotoxic T cells to induce cell death in target cells?
What type of cell is responsible for producing antibodies?
What type of cell is responsible for producing antibodies?
What type of antibody primarily constitutes the serum component of a secondary immune response?
What type of antibody primarily constitutes the serum component of a secondary immune response?
Against what type of pathogens are interferons most effective?
Against what type of pathogens are interferons most effective?
Considering the relationship between volume and pressure as described by Boyle's Law, what effect would a decrease in lung volume have on intrapulmonary pressure?
Considering the relationship between volume and pressure as described by Boyle's Law, what effect would a decrease in lung volume have on intrapulmonary pressure?
How would the affinity of hemoglobin for oxygen be affected in metabolically active tissues with increased carbon dioxide (CO2) levels and decreased pH?
How would the affinity of hemoglobin for oxygen be affected in metabolically active tissues with increased carbon dioxide (CO2) levels and decreased pH?
Which of the following best describes the cooperative binding of oxygen to hemoglobin?
Which of the following best describes the cooperative binding of oxygen to hemoglobin?
What is the functional consequence of the absence of cartilage on the posterior aspect of the trachea?
What is the functional consequence of the absence of cartilage on the posterior aspect of the trachea?
How does increased altitude affect alveolar partial pressure of oxygen ($P_{O2}$), and what is the physiological consequence for oxygen diffusion?
How does increased altitude affect alveolar partial pressure of oxygen ($P_{O2}$), and what is the physiological consequence for oxygen diffusion?
Flashcards
Lymphatic tissue
Lymphatic tissue
A specialized form of reticular connective tissue that contains large numbers of lymphocytes.
Lymphatic Vessel Structure
Lymphatic Vessel Structure
Lymphatic capillaries have greater permeability than blood capillaries.
Lymphatic Drainage Regions
Lymphatic Drainage Regions
The right lymphatic duct drains the right side of the body inferior to the ribs.
Cisterna Chyli
Cisterna Chyli
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Route of Fluid Flow
Route of Fluid Flow
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Role of Thymus
Role of Thymus
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Thymus Size with Age
Thymus Size with Age
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Lymph Flow in Node
Lymph Flow in Node
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Foreign Substances in Lymph Node
Foreign Substances in Lymph Node
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NOT innate immunity
NOT innate immunity
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Internal defenses against microbes
Internal defenses against microbes
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Interferons
Interferons
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Natural Killer Cells
Natural Killer Cells
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Phagocytosis Phases
Phagocytosis Phases
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Killing Microbes
Killing Microbes
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Complement Proteins Production
Complement Proteins Production
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Not a function of the complement system
Not a function of the complement system
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Complement System Activation
Complement System Activation
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Immunocompetent Cell
Immunocompetent Cell
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T and B Cell Development
T and B Cell Development
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Not a function of adaptive immunity
Not a function of adaptive immunity
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Antigen context
Antigen context
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MHC Molecules
MHC Molecules
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Endogenous Antigens
Endogenous Antigens
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T cell activation
T cell activation
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Effector T cells
Effector T cells
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Cytotoxic T cell targets
Cytotoxic T cell targets
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How Cytotoxic T cells kill
How Cytotoxic T cells kill
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T Cell in Both Responses
T Cell in Both Responses
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An antibody combines specifically with the
An antibody combines specifically with the
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Antibodies Differ
Antibodies Differ
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Antibodies disable antigens in any of the following ways except:
Antibodies disable antigens in any of the following ways except:
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Descendant of B cell...
Descendant of B cell...
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Secondary Response
Secondary Response
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Antibody in Secondary Response
Antibody in Secondary Response
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Membrane attack complex
Membrane attack complex
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Cytotoxic T Cells substances except
Cytotoxic T Cells substances except
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Antibodies are produced by
Antibodies are produced by
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Serum Component
Serum Component
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Interferons are effective against
Interferons are effective against
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Lymphatic system.
Lymphatic system.
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Lymph node area
Lymph node area
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Splenic Parts
Splenic Parts
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Cell capable
Cell capable
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The organ is the indicated organ in this figure is the
The organ is the indicated organ in this figure is the
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Study Notes
- Lymphatic tissue is a specialized form of reticular connective tissue with a large number of lymphocytes.
- Lymphatic capillaries have greater permeability than blood capillaries
- The right lymphatic duct does not drain the right side of the body inferior to the ribs.
- The thoracic duct begins as the cisterna chyli, which receives lymph from the lumbar and intestinal trunks.
- The route of fluid flow is: interstitial space -> lymphatic capillaries -> lymphatic vessels -> lymph nodes -> lymphatic ducts -> junction of internal jugular and subclavian veins
- The thymus matures T cells.
- The thymus undergoes atrophy as you age
- As lymph travels through a lymph node, it flows through: afferent lymphatic vessels-> subcapsular sinus -> trabecular sinuses -> medullary sinuses -> efferent lymphatic vessels.
- Foreign substances that enter a lymph node in lymph are trapped and destroyed.
- Development of antibodies against invaders is NOT a component of innate immunity.
- Lysozyme in saliva is NOT an internal defense that provides protection against microbes that penetrate the skin and mucous membranes
- Interferons are antimicrobial proteins that prevent viral replication
- Lymphocytes are natural killer cells.
- The correct order for the phases of phagocytosis is: chemotaxis -> adherence -> ingestion -> digestion -> killing.
- Microbes are killed following ingestion by a phagocyte by digestive enzymes dissolving it.
- Complement proteins are produced in the liver and circulating in the blood.
- Stimulating fever which destroys microbes is NOT a means for the complement system to destroy microbes.
- The complement system is activated when they become activated only when split by enzymes into active fragments.
- Immunocompetent means ready to carry out adaptive immune responses.
- T cells develop in the thymus and B cells in the bone marrow.
- Cell-mediated immunity, phagocytes are NOT produced, cytotoxic T cells directly attack invading antigens.
- In antigen processing, antigenic proteins are broken down into peptide fragments that then form antigen-MHC molecules and the insertion of the antigen-MHC complex into the plasma membrane is called antigen presentation.
- Major histocompatibility complex molecules act as self-antigens.
- MHC molecules on the plasma membrane are NOT an example of endogenous antigens
- Binding of a T cell to an antigen-MHC complex is the first signal in activation.
- Cytotoxic T cells are the effector cells of a T cell clone that attack other body cells that have been infected with the antigen.
- Cytotoxic T cells attack tumor cells and transplanted cells besides cells infected by microbes.
- Cytotoxic T cells kill infected target cells by delivering a lethal hit.
- Helper T cells participate in both cell-mediated and antibody-mediated immune responses.
- An antibody combines specifically with the epitope on the antigen that triggered the antibody's production.
- The five classes of antibodies differ in chemical structure and specific biological role.
- Antibodies disable antigens in any of the following ways except inhibit complement.
- Memory B cell is a descendant of a B cell that remains after immune response and is ready to respond rapidly and forcefully should the same antigen enter body in future.
- The secondary response to an antigen is faster and stronger than the primary response.
- The IgG antibody responds most strongly during the secondary response.
- C3a is NOT directly involved in the formation of a membrane attack complex
- Cytotocix T cells release perfonin, granzymes, and lymphotoxin BUT NOT lysozyme
- Antibodies are produced by plasma cells
- The serum component of a secondary response consists mainly of IgG antibodies.
- Interferons are effective against viruses.
- The indicated structure in the lymphatic system figure is the cisterna chili.
- The indicated area in the lymph node figure is the germinal center
- The indicated structure of the spleen is the white pulp.
- Macrophages are capable of the immune response process
- The indicated organ structure is the thymus
- Air molecules enter into the nasal cavity, then into a series of groove-like passageways - the superior, middle, and inferior nasal meatuses.
- The nose does NOT dry incoming air
- Maxillary cartilages are NOT a cartilage of the nose.
- Paranasal sinuses serve as a resonating chamber and produce mucus
- The nose traps particulate matter and mucus reduces drying to moisten and clean inhaled air before it enters the rest of the respiratory tract.
- The superior and inferior borders of the pharynx are the nasal cavity and esophagus.
- The epiglottis is a large, leafshaped piece of elastic cartilage that can move up and down like a trap door.
- The main function of the vocal folds is to produce sounds.
- The benefit of not having cartilage between the trachea and the esophagus is that both increases flexibility of the trachea and prevents the tracheal wall from collapsing.
- The path taken by air molecules into and through the bronchial tree is: trachea-> carina -> primary bronchi -> secondary bronchi -> tertiary bronchi -> bronchioles -> terminal bronchioles
- The pleural cavity is NOT between the parietal pleura and chest wall
- The path taken by air molecules as they travel from terminal bronchioles to alveoli is: terminal bronchioles -> respiratory bronchioles -> alveolar ducts -> alveoli
- If the volume of the cylinder decreased from 1 liter to 1/4 liter, the pressure would increase to 4 atm
- The most important muscle that powers breathing is the diaphragm.
- Volume increases cause air to enter the lungs during inhalation.
- Elastic fibers within parietal pleura do NOT produce the elastic recoil of the thoracic wall and lungs, this DOES include recoil of stretched elastic fibers, surface tension in alveoli, passive spring back of thoracic wall
- Airflow into alveoli is greater with higher compliance of the lungs and larger bronchioles.
- The apparatus commonly used to measure the volume of air exchanged during breathing and to measure the respiratory rate is a spirometer.
- The anatomic dead space is air remaining in the conducting airways.
- Inspiratory reserve volume is NOT title volume plus full inspiration
- The quantity of a gas that will dissolve in a liquid is proportional to the partial pressure of the gas and its solubility, this is described by Henry's law AND Dalton’s law describes the pressure of a specific gas in a mixture.
- Oxygen enters pulmonary capillaries from alveolar air and enters tissue cells from systemic capillaries due to the partial pressure differences of oxygen.
- Blood pressure differences do NOT affect the rates of diffusion of oxygen and carbon dioxide.
- Increased altitude causes decreased partial pressure of oxygen.
- Oxygen transport through the blood can occur dissolved in blood plasma and bound to hemoglobin.
- Partial pressure of oxygen is the most important factor in determining how much oxygen binds to hemoglobin.
- It is false that in tissue capillaries, where PO2 is high, a lot of O2 binds to hemoglobin.
- Carbon dioxide transport through the blood can occur EXCEPT when bound to chloride
- The concentration of HCO3- is expected to be higher in blood plasma taken from a systemic vein not an artery.
- The phrenic nerves convey impulses from the respiratory center to the diaphragm.
- The basic rhythm of respiration is controlled by: medullary rhythmicity area.
- The statement that apneustic area controls the pneumotaxic area regarding the apneustic and pneumotaxic areas is that its INCORRECT the pneumotaxic area controls the apneustic area..
- Central chemoreceptors of respiration are located in the medulla oblongata.
- The chemical chloride does not stimulate peripheral chemoreceptors.
- The normal arterial blood PCO2 is about 40 mmHg.
- The rate of breathing increases as depth increases when PCO2 becomes elevated.
- The inflation reflex prevents insufficient inflation of the lungs.
- Proteins buffer body fluids and bicarbonate ions release H+ to increase acidity in order to maintain the pH of body fluids.
- Hyperventilation results in respiratory acidosis is a false statement about acidosis and alkalosis.
- The nasal cavity is lined with pseudostratified columnar epithelium.
- A bronchopulmonary segment is an area of the lung supplied by a tertiary bronchus.
- As the volume of a specific amount of gas increases its pressure decreases, according to Boyle's Law
- The air that remains in the noncollapsible airways is the residual volume.
- The law that states each gas in a mixture exerts its own pressure as if no other gases were present is Dalton's law.
- Gas exchange between systemic capillaries and tissue cells is known as internal respiration.
- The greatest percentage of CO2 is transported in the blood as bicarbonate ions.
- The apneustic area is located in the pons.
- Hyperventilation will result if PCO2 is increased.
- An increase of CO2 in body fluids increases H+ concentration and lowers pH.
- The area indicated in the throat figure is the oropharynx.
- The structure indicated in the laryngeal structure is the epiglottis
- Type II alveolar cells function in surfactant secretion.
- According to the oxygen-hemoglobin dissociation curve shown in this figure, as pH decreases oxygen binds less tightly with hemoglobin so more O2 is available to the tissues
- The structure in the lung is the left primary bronchus.
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