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Questions and Answers
What is the drug classification of Lurasidone (Latuda)?
What is the drug classification of Lurasidone (Latuda)?
- Anxiolytic
- Mood stabilizer
- Antipsychotic (correct)
- Antidepressant
What are the indications for Lurasidone (Latuda)?
What are the indications for Lurasidone (Latuda)?
- Anxiety
- Post-traumatic stress disorder
- Depression (bipolar disorder) (correct)
- Schizophrenia (correct)
What is one major side effect of Lurasidone (Latuda)?
What is one major side effect of Lurasidone (Latuda)?
NMS
Which of the following is a nursing responsibility when administering Lurasidone (Latuda)?
Which of the following is a nursing responsibility when administering Lurasidone (Latuda)?
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What drug action is associated with Lurasidone (Latuda)?
What drug action is associated with Lurasidone (Latuda)?
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Which conditions are contraindicated for using Lurasidone (Latuda)?
Which conditions are contraindicated for using Lurasidone (Latuda)?
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List one caution when prescribing Lurasidone (Latuda).
List one caution when prescribing Lurasidone (Latuda).
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What interactions should be considered when administering Lurasidone (Latuda)?
What interactions should be considered when administering Lurasidone (Latuda)?
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Study Notes
Lurasidone (Latuda) Overview
- Lurasidone is an antipsychotic medication classified as a benzisothiazole.
- It is available in oral dosage (PO) and is categorized as a Category B drug for pregnancy.
Indications
- Prescribed for treating schizophrenia.
- Used for managing depression in bipolar disorder.
Side Effects
- May lead to serious conditions like Neuroleptic Malignant Syndrome (NMS), seizures, and suicidal thoughts.
- Common side effects include akathisia, drowsiness, agitation, anxiety, and cognitive motor impairment.
- Other side effects: dizziness, dystonia, tardive dyskinesia (TD), blurred vision, changes in heart rate (HR), blood pressure (BP) variations, nausea, and esophageal dysmotility.
- Skin reactions such as rash and pruritus can occur, along with metabolic changes such as increased blood sugar, higher prolactin levels, and risks of agranulocytosis and anemia.
- Potential for weight gain and dyslipidemia.
Nursing Responsibilities
- Monitor for elevated prolactin and glucose levels throughout treatment.
Drug Action
- Functions by antagonizing dopamine and serotonin receptors, contributing to its antipsychotic effects.
Contraindications
- Not suitable for individuals with hypersensitivity to components or those using liver enzyme inhibitors concurrently.
Cautions
- Use with caution in patients with renal impairment, past suicidal behavior, diabetes, dehydration, or a history of leukopenia and neutropenia.
- In elderly patients, particularly those with dementia, benefits must outweigh risks.
- Use in adolescents taking antidepressants requires careful consideration.
Drug Interactions
- Concurrent use with liver enzyme inhibitors can elevate lurasidone levels.
- Increased risk of CNS depression when combined with alcohol, sedatives, opioids, antidepressants, or antihistamines.
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