Questions and Answers
What classification does Loratadine (Claritin) fall under?
What are the actions of Loratadine?
Long acting nonsedating antihistamine with selective peripheral H1 receptor sites blocking histamine release.
What are the uses of Loratadine?
Relief of symptoms of seasonal allergic rhinitis, idiopathic chronic urticaria.
The route of administration for Loratadine is _____.
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What are the adverse effects of Loratadine?
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What are the contraindications for using Loratadine?
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In which conditions should Loratadine be used cautiously?
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What interactions should be noted with Loratadine?
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What education should be provided to patients and families regarding Loratadine?
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Study Notes
Classifications
- Loratadine is a nonsedating antihistamine and functions as an H1 receptor antagonist.
Actions
- Acts as a long-acting antihistamine, selectively blocking peripheral H1 receptor sites to prevent histamine release.
Uses
- Primarily provides relief from symptoms associated with seasonal allergic rhinitis and idiopathic chronic urticaria.
Route/Administration
- Administered orally (PO) and should be taken on an empty stomach, either one hour before or two hours after meals.
Adverse Effects
- CNS: May cause dizziness, dry mouth, fatigue, somnolence, altered salivation and lacrimation, thirst, flushing, anxiety, depression, and impaired concentration.
- Cardiovascular (CV): Risk of hypertension, palpitations, syncope, and tachycardia.
- Gastrointestinal (GI): Possible effects include nausea, vomiting, flatulence, abdominal distress, constipation, diarrhea, weight changes, and dyspepsia.
- Special Senses: Blurred vision, earache, tinnitus, and ear pain may occur.
- Skin: Potential for rash and photosensitivity.
Contraindications
- Not suitable for individuals with hypersensitivity to loratadine or for those who are lactating.
Cautious Use
- Use with caution in patients with hepatic or renal impairment, renal disease, renal failure, asthma, and those who are pregnant (classified as Pregnancy Category B).
Interactions
- Not specified, but potential for interactions exists. Care should be taken with concurrent medications.
Patient and Family Education
- Important to inform that loratadine can induce significant drowsiness, especially in older adults and patients with liver or kidney impairment.
- Advise patients about the potential additive effects when consuming alcohol or other CNS depressants concurrently.
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Description
Test your knowledge about Loratadine, a nonsedating antihistamine. This quiz covers classifications, actions, uses, and administration routes of this common allergy medication. Perfect for students and healthcare professionals alike.
