Loop Diuretics and Diuretic Resistance
31 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a determinant for cardiac output?

  • Heart rate
  • Stroke volume
  • Preload
  • All of the above (correct)

Which of the following is NOT an initial insult that can lead to heart failure?

  • Genetic disorders
  • Ischemic cardiomyopathy
  • Valvular disease
  • Hypertension (correct)

What is the formula for cardiac output?

  • CO = HR / SV
  • CO = HR - SV
  • CO = HR * SV (correct)
  • CO = HR + SV

Which type of heart failure is characterized by thin heart walls?

<p>Systolic failure (B)</p> Signup and view all the answers

Which type of heart failure is characterized by thick heart walls?

<p>Diastolic failure (C)</p> Signup and view all the answers

What is the definition of heart failure?

<p>A syndrome caused by cardiac dysfunction resulting in symptoms such as fluid retention and shortness of breath (C)</p> Signup and view all the answers

Which stage of heart failure is characterized by severe symptoms at rest and requires advanced treatment options like transplantation?

<p>Stage D (A)</p> Signup and view all the answers

Which hormone stimulates the conversion of Angiotensin 1 to Angiotensin 2 via ACE?

<p>Renin (D)</p> Signup and view all the answers

Which of the following hormones increases volume by retention of sodium and water in the kidneys?

<p>Vasopressin (B)</p> Signup and view all the answers

Which neurohormone is responsible for down regulation of the beta receptor and can cause arrhythmias?

<p>Norepinephrine (D)</p> Signup and view all the answers

Which hormone causes loss of flow-mediated vasodilation, thickening and rigidity of arteries, and increased afterload?

<p>Angiotensin 2 (A)</p> Signup and view all the answers

Which of the following is the preferred initial treatment for Stage C heart failure with reduced ejection fraction (HFrEF)?

<p>ARNI (D)</p> Signup and view all the answers

Which drug should be considered for persistently symptomatic black patients with HFrEF despite ARNI, beta-blocker, and aldosterone antagonist therapy?

<p>Hydralazine + isosorbide dinitrate (C)</p> Signup and view all the answers

What is the target daily dose of carvedilol for HFrEF?

<p>50 mg (D)</p> Signup and view all the answers

What is the target daily dose of metoprolol succinate (ER) for HFrEF?

<p>200 mg (C)</p> Signup and view all the answers

Which medication has demonstrated reductions in cardiovascular death and hospitalizations due to HF, including additive benefit with MRAs and ARNi?

<p>SGLT2i (C)</p> Signup and view all the answers

Which medication has the highest reduction in mortality according to the guideline?

<p>Beta-blocker (B)</p> Signup and view all the answers

Which medication has a reduction in hospitalizations of 31% according to the guideline?

<p>ACEi/ARB (D)</p> Signup and view all the answers

Which medication is recommended for any patient with HFpEF without contraindications?

<p>SGLT2i (C)</p> Signup and view all the answers

Which of the following is NOT a major contributor to anorexia in patients with advanced HF?

<p>Hypotension (D)</p> Signup and view all the answers

True or False: Cardiac rehabilitation has been shown to improve clinical status and outcomes in patients with HF.

<p>True (A)</p> Signup and view all the answers

Which of the following is an independent predictor of mortality in patients with HF?

<p>Depression (C)</p> Signup and view all the answers

Which of the following is NOT a symptom of acute decompensated heart failure (ADHF)?

<p>Hypertension (B)</p> Signup and view all the answers

Which mineralocorticoid receptor antagonist is a non-selective antagonist on mineralocorticoid and progesterone, androgen receptors?

<p>Spironolactone (C)</p> Signup and view all the answers

Which mineralocorticoid receptor antagonist is a selective antagonist on mineralocorticoid receptor in the kidney, heart, and vessels?

<p>Eplerenone (A)</p> Signup and view all the answers

Which class of medications is recommended for patients with chronic symptomatic HFrEF Class 2 or 3 who tolerate ACEi or ARB, to reduce mortality and morbidity?

<p>ARNI/ACEi/ARB (A)</p> Signup and view all the answers

Which beta-blocker is the least lipophilic?

<p>Bisoprolol (A)</p> Signup and view all the answers

Which diuretic has increased oral bioavailability, longer half-life, and beneficial effects on myocardial fibrosis, aldosterone production, sympathetic activation, ventricular remodeling, and natriuretic peptides?

<p>Torsemide (B)</p> Signup and view all the answers

What is the initial goal of diuretic therapy in heart failure patients?

<p>Net loss of 500 mL to 1 L per day (B)</p> Signup and view all the answers

Which combination of medications is recommended to reduce mortality in self-described African American patients with Class 3-4 heart failure receiving optimal therapy with ACEi and beta-blocker, unless contraindicated?

<p>Vericiguat + hydralazine (D)</p> Signup and view all the answers

Which medication is approved to reduce hospitalizations in patients with stable heart failure and an EF < 35%, a resting HR of at least 70 BPM on maximally tolerated beta blockers?

<p>Ivabradine (A)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser