31 Questions
Which of the following is a determinant for cardiac output?
All of the above
Which of the following is NOT an initial insult that can lead to heart failure?
Hypertension
What is the formula for cardiac output?
CO = HR * SV
Which type of heart failure is characterized by thin heart walls?
Systolic failure
Which type of heart failure is characterized by thick heart walls?
Diastolic failure
What is the definition of heart failure?
A syndrome caused by cardiac dysfunction resulting in symptoms such as fluid retention and shortness of breath
Which stage of heart failure is characterized by severe symptoms at rest and requires advanced treatment options like transplantation?
Stage D
Which hormone stimulates the conversion of Angiotensin 1 to Angiotensin 2 via ACE?
Renin
Which of the following hormones increases volume by retention of sodium and water in the kidneys?
Vasopressin
Which neurohormone is responsible for down regulation of the beta receptor and can cause arrhythmias?
Norepinephrine
Which hormone causes loss of flow-mediated vasodilation, thickening and rigidity of arteries, and increased afterload?
Angiotensin 2
Which of the following is the preferred initial treatment for Stage C heart failure with reduced ejection fraction (HFrEF)?
ARNI
Which drug should be considered for persistently symptomatic black patients with HFrEF despite ARNI, beta-blocker, and aldosterone antagonist therapy?
Hydralazine + isosorbide dinitrate
What is the target daily dose of carvedilol for HFrEF?
50 mg
What is the target daily dose of metoprolol succinate (ER) for HFrEF?
200 mg
Which medication has demonstrated reductions in cardiovascular death and hospitalizations due to HF, including additive benefit with MRAs and ARNi?
SGLT2i
Which medication has the highest reduction in mortality according to the guideline?
Beta-blocker
Which medication has a reduction in hospitalizations of 31% according to the guideline?
ACEi/ARB
Which medication is recommended for any patient with HFpEF without contraindications?
SGLT2i
Which of the following is NOT a major contributor to anorexia in patients with advanced HF?
Hypotension
True or False: Cardiac rehabilitation has been shown to improve clinical status and outcomes in patients with HF.
True
Which of the following is an independent predictor of mortality in patients with HF?
Depression
Which of the following is NOT a symptom of acute decompensated heart failure (ADHF)?
Hypertension
Which mineralocorticoid receptor antagonist is a non-selective antagonist on mineralocorticoid and progesterone, androgen receptors?
Spironolactone
Which mineralocorticoid receptor antagonist is a selective antagonist on mineralocorticoid receptor in the kidney, heart, and vessels?
Eplerenone
Which class of medications is recommended for patients with chronic symptomatic HFrEF Class 2 or 3 who tolerate ACEi or ARB, to reduce mortality and morbidity?
ARNI/ACEi/ARB
Which beta-blocker is the least lipophilic?
Bisoprolol
Which diuretic has increased oral bioavailability, longer half-life, and beneficial effects on myocardial fibrosis, aldosterone production, sympathetic activation, ventricular remodeling, and natriuretic peptides?
Torsemide
What is the initial goal of diuretic therapy in heart failure patients?
Net loss of 500 mL to 1 L per day
Which combination of medications is recommended to reduce mortality in self-described African American patients with Class 3-4 heart failure receiving optimal therapy with ACEi and beta-blocker, unless contraindicated?
Vericiguat + hydralazine
Which medication is approved to reduce hospitalizations in patients with stable heart failure and an EF < 35%, a resting HR of at least 70 BPM on maximally tolerated beta blockers?
Ivabradine
Test your knowledge on loop diuretics and their use in diuretic resistance. Learn about the differences between loop diuretics and thiazide diuretics, including their common prescriptions and benefits. Explore the unique properties of torsemide and its effects on various aspects of cardiovascular health.
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