Podcast
Questions and Answers
What is the purpose of long term potentiation (LTP)?
What is the purpose of long term potentiation (LTP)?
- To examine learning and memory at the basic level of the neuron
- To explore changes at the level of the neuron (correct)
- To measure population EPSP of the cells in the dentate gyrus
- To stimulate axons in the hippocampal formation
What is the main assumption underlying the concept of long term potentiation (LTP)?
What is the main assumption underlying the concept of long term potentiation (LTP)?
- All behavior is associated with some underlying physiological activity (correct)
- Memory is not represented by any type of permanent change
- The nervous system changes as a result of rapid stimulation
- Learning only occurs in the hippocampal formation
Which part of the rat's hippocampal formation is stimulated many times in rapid succession during long term potentiation (LTP)?
Which part of the rat's hippocampal formation is stimulated many times in rapid succession during long term potentiation (LTP)?
- Neurons in the cerebral cortex
- Dentate gyrus
- Entorhinal cortex (correct)
- Hippocampal cells
What is measured when a single pulse is sent via the axons of the entorhinal cells during long term potentiation?
What is measured when a single pulse is sent via the axons of the entorhinal cells during long term potentiation?
What does long term potentiation (LTP) aim to represent at the level of the neuron?
What does long term potentiation (LTP) aim to represent at the level of the neuron?
In long term potentiation (LTP), what leads to an increase in activity in the dentate gyrus?
In long term potentiation (LTP), what leads to an increase in activity in the dentate gyrus?
What is the main function of EPSPs (excitatory post synaptic potentials)?
What is the main function of EPSPs (excitatory post synaptic potentials)?
What is the significance of a significantly higher population EPSP after stimulating the axons with several pulses in quick succession?
What is the significance of a significantly higher population EPSP after stimulating the axons with several pulses in quick succession?
What is the primary manifestation of neural plasticity in the hippocampus?
What is the primary manifestation of neural plasticity in the hippocampus?
What are the conditions necessary for long term potentiation to occur?
What are the conditions necessary for long term potentiation to occur?
What is the mechanism through which NMDA has its effects in long term potentiation?
What is the mechanism through which NMDA has its effects in long term potentiation?
Which neurotransmitter is released in the synapse and binds to multiple important receivers in long term potentiation?
Which neurotransmitter is released in the synapse and binds to multiple important receivers in long term potentiation?
What is the effect of glutamate activating NMDA receptors with a partly depolarized dendritic membrane?
What is the effect of glutamate activating NMDA receptors with a partly depolarized dendritic membrane?
What was found in hippocampus and subsequently demonstrated in numerous regions of cortex, allowing sustainable strengthening of synapses between neurons?
What was found in hippocampus and subsequently demonstrated in numerous regions of cortex, allowing sustainable strengthening of synapses between neurons?
What happens when axons that make connection to the pyramidal neurons of the hippocampus are stimulated at high frequency?
What happens when axons that make connection to the pyramidal neurons of the hippocampus are stimulated at high frequency?
What is required for Ca2+ channels to open when glutamate activates NMDA receptors?
What is required for Ca2+ channels to open when glutamate activates NMDA receptors?
What is long term potentiation (LTP) and how is it experimentally induced?
What is long term potentiation (LTP) and how is it experimentally induced?
What is the significance of long term potentiation (LTP) in the context of learning and memory?
What is the significance of long term potentiation (LTP) in the context of learning and memory?
What is the role of glutamate and NMDA receptors in long term potentiation (LTP)?
What is the role of glutamate and NMDA receptors in long term potentiation (LTP)?
How does long term potentiation (LTP) affect the activity in the dentate gyrus?
How does long term potentiation (LTP) affect the activity in the dentate gyrus?
What is the primary manifestation of neural plasticity at the level of the neuron?
What is the primary manifestation of neural plasticity at the level of the neuron?
What is the neurological basis of learning explored at the basic level of the neuron?
What is the neurological basis of learning explored at the basic level of the neuron?
What are the two important criteria that must be met for long term potentiation to occur?
What are the two important criteria that must be met for long term potentiation to occur?
What is the primary manifestation of neural plasticity in the hippocampus?
What is the primary manifestation of neural plasticity in the hippocampus?
What is the mechanism through which NMDA has its effects in long term potentiation?
What is the mechanism through which NMDA has its effects in long term potentiation?
What is the significance of a significantly higher population EPSP after stimulating the axons with several pulses in quick succession?
What is the significance of a significantly higher population EPSP after stimulating the axons with several pulses in quick succession?
What is the effect of glutamate activating NMDA receptors with a partly depolarized dendritic membrane?
What is the effect of glutamate activating NMDA receptors with a partly depolarized dendritic membrane?
What is the function of EPSPs (excitatory post synaptic potentials) in a neuron?
What is the function of EPSPs (excitatory post synaptic potentials) in a neuron?
What is the role of the dentate gyrus in long term potentiation?
What is the role of the dentate gyrus in long term potentiation?
What happens when axons that make connection to the pyramidal neurons of the hippocampus are stimulated at high frequency?
What happens when axons that make connection to the pyramidal neurons of the hippocampus are stimulated at high frequency?
What was found in the hippocampus and subsequently demonstrated in numerous regions of cortex, allowing sustainable strengthening of synapses between neurons?
What was found in the hippocampus and subsequently demonstrated in numerous regions of cortex, allowing sustainable strengthening of synapses between neurons?
What are the characteristics of the mechanism known as LTP (long term potentiation)?
What are the characteristics of the mechanism known as LTP (long term potentiation)?
