Location of Primary and Secondary Osteosarcomas
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Questions and Answers

Where do primary osteosarcomas typically occur in the appendicular skeleton?

  • In the metadiaphysis of long bones (correct)
  • In the diaphysis of long bones
  • In the metaphysis of short bones
  • In the epiphysis of long bones

    • Which bone location is a common site for secondary osteosarcomas?

  • Pelvis (correct)
  • Radius
  • Patella
  • Clavicle

    • What is the distribution of intramedullary/central osteosarcomas?

  • ~80% (correct)
  • ~10%
  • ~50%
  • ~30%

    • Which of the following is a rare type of osteosarcoma according to the text?

    <p>Extraskeletal osteosarcoma</p> Signup and view all the answers

    What are skip metastases associated with in high-grade osteosarcomas?

    <p>Non-contiguous smaller tumour foci in the same bone or adjacent bone</p> Signup and view all the answers

    What is the most common subtype of primary osteosarcoma discussed in the article?

    <p>Osteoblastic osteosarcoma</p> Signup and view all the answers

    What is a characteristic macroscopic appearance of osteosarcomas?

    <p>Areas of haemorrhage, fibrosis, and cystic degeneration</p> Signup and view all the answers

    Which marker may be elevated in serum with advanced osteosarcoma?

    <p>Alkaline phosphatase (ALP)</p> Signup and view all the answers

    What is a common site of origin within the bone for primary osteosarcomas?

    <p>Intramedullary/central location</p> Signup and view all the answers

    What is a key feature of the microscopic appearance of high-grade conventional osteosarcomas?

    <p>Cellular pleomorphism and mitoses</p> Signup and view all the answers

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