Location of Primary and Secondary Osteosarcomas
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Questions and Answers

Where do primary osteosarcomas typically occur in the appendicular skeleton?

  • In the metadiaphysis of long bones (correct)
  • In the diaphysis of long bones
  • In the metaphysis of short bones
  • In the epiphysis of long bones

Which bone location is a common site for secondary osteosarcomas?

  • Pelvis (correct)
  • Radius
  • Patella
  • Clavicle

What is the distribution of intramedullary/central osteosarcomas?

  • ~80% (correct)
  • ~10%
  • ~50%
  • ~30%

Which of the following is a rare type of osteosarcoma according to the text?

<p>Extraskeletal osteosarcoma (A)</p> Signup and view all the answers

What are skip metastases associated with in high-grade osteosarcomas?

<p>Non-contiguous smaller tumour foci in the same bone or adjacent bone (B)</p> Signup and view all the answers

What is the most common subtype of primary osteosarcoma discussed in the article?

<p>Osteoblastic osteosarcoma (C)</p> Signup and view all the answers

What is a characteristic macroscopic appearance of osteosarcomas?

<p>Areas of haemorrhage, fibrosis, and cystic degeneration (A)</p> Signup and view all the answers

Which marker may be elevated in serum with advanced osteosarcoma?

<p>Alkaline phosphatase (ALP) (A)</p> Signup and view all the answers

What is a common site of origin within the bone for primary osteosarcomas?

<p>Intramedullary/central location (A)</p> Signup and view all the answers

What is a key feature of the microscopic appearance of high-grade conventional osteosarcomas?

<p>Cellular pleomorphism and mitoses (C)</p> Signup and view all the answers

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