Podcast
Questions and Answers
What is the main purpose of selection and breeding systems in livestock populations?
What is the main purpose of selection and breeding systems in livestock populations?
To improve genetic makeup for enhanced productivity, disease resistance, and overall quality.
Differentiate between individual selection and family selection.
Differentiate between individual selection and family selection.
Individual selection focuses on an animal's specific performance traits, while family selection considers the average performance of an entire family.
Explain the role of progeny testing in selection methods.
Explain the role of progeny testing in selection methods.
Progeny testing evaluates an individual's breeding value based on the performance of its offspring.
What is the potential downside of inbreeding in livestock populations?
What is the potential downside of inbreeding in livestock populations?
How does outcrossing differ from crossbreeding?
How does outcrossing differ from crossbreeding?
What is the significance of differentiating between qualitative and quantitative traits in genetic control?
What is the significance of differentiating between qualitative and quantitative traits in genetic control?
What role does environmental management play in the context of breeding animals?
What role does environmental management play in the context of breeding animals?
How can poor nutrition lead to the expression of dormant genetic disorders in animals?
How can poor nutrition lead to the expression of dormant genetic disorders in animals?
Explain the significance of housing conditions in poultry regarding their health outcomes.
Explain the significance of housing conditions in poultry regarding their health outcomes.
What are some practical solutions to mitigate stress in pigs that might lead to inherited conditions?
What are some practical solutions to mitigate stress in pigs that might lead to inherited conditions?
What did Angus John Bateman's research on Drosophila melanogaster contribute to the field of phenotypic selection?
What did Angus John Bateman's research on Drosophila melanogaster contribute to the field of phenotypic selection?
Identify and describe the impact of management practices on influencing genetic predispositions in animals.
Identify and describe the impact of management practices on influencing genetic predispositions in animals.
What is the significance of autosomal recessive inheritance in the context of inherited disorders in farm animals?
What is the significance of autosomal recessive inheritance in the context of inherited disorders in farm animals?
Explain how artificial insemination (AI) exacerbates the spread of undesirable genes in livestock.
Explain how artificial insemination (AI) exacerbates the spread of undesirable genes in livestock.
Describe the characteristics and outcomes associated with Bovine Brachyspina Syndrome (BBS).
Describe the characteristics and outcomes associated with Bovine Brachyspina Syndrome (BBS).
What role does genetic screening play in managing inherited diseases in farm animals?
What role does genetic screening play in managing inherited diseases in farm animals?
Identify key management strategies to prevent the dominance of autosomal recessive disorders in livestock populations.
Identify key management strategies to prevent the dominance of autosomal recessive disorders in livestock populations.
What are the clinical signs of Bovine Leukocyte Adhesion Deficiency (BLAD) in affected cattle?
What are the clinical signs of Bovine Leukocyte Adhesion Deficiency (BLAD) in affected cattle?
Discuss how vaccination and health monitoring contribute to the management of inherited diseases in farm animals.
Discuss how vaccination and health monitoring contribute to the management of inherited diseases in farm animals.
How can record keeping assist in the identification of at-risk animals in the context of inherited diseases?
How can record keeping assist in the identification of at-risk animals in the context of inherited diseases?
What is the primary cause of Porcine Stress Syndrome (PSS)?
What is the primary cause of Porcine Stress Syndrome (PSS)?
Describe the inheritance pattern of autosomal recessive disorders.
Describe the inheritance pattern of autosomal recessive disorders.
How do genetic testing and selection help prevent single gene disorders in breeding programs?
How do genetic testing and selection help prevent single gene disorders in breeding programs?
What distinguishes multifactorial disorders from single-gene disorders?
What distinguishes multifactorial disorders from single-gene disorders?
Give an example of a multifactorial disorder and mention its contributing factors.
Give an example of a multifactorial disorder and mention its contributing factors.
What is the significance of the X chromosome in X-linked disorders?
What is the significance of the X chromosome in X-linked disorders?
What role do environmental factors play in multifactorial disorders?
What role do environmental factors play in multifactorial disorders?
How do breeders aim to minimize the risk of multifactorial disorders?
How do breeders aim to minimize the risk of multifactorial disorders?
What is the inheritance pattern observed in Huntington's Disease?
What is the inheritance pattern observed in Huntington's Disease?
In the context of breeding, why is the selection of carriers important?
In the context of breeding, why is the selection of carriers important?
Flashcards
Animal Breeding
Animal Breeding
The process of improving livestock genetics to boost productivity, disease resistance, and overall quality. It heavily relies on selection and breeding systems.
Selection
Selection
Choosing individuals to become parents and pass their genes to the next generation.
Individual Selection
Individual Selection
Focusing on an animal's individual performance for specific traits. Most effective for traits with high heritability.
Family Selection
Family Selection
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Outbreeding
Outbreeding
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Crossbreeding
Crossbreeding
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Autosomal Recessive Inheritance
Autosomal Recessive Inheritance
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Bovine Brachyspina Syndrome (BBS)
Bovine Brachyspina Syndrome (BBS)
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Bovine Leukocyte Adhesion Deficiency (BLAD)
Bovine Leukocyte Adhesion Deficiency (BLAD)
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Genetic Screening
Genetic Screening
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Selective Breeding
Selective Breeding
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Early Diagnosis and Identification of At-Risk Animals
Early Diagnosis and Identification of At-Risk Animals
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Management and Disease Control
Management and Disease Control
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Regular Monitoring and Health Tracking
Regular Monitoring and Health Tracking
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Environmental Control of Inherited Disorders
Environmental Control of Inherited Disorders
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Nutrition's Role in Genetic Disorders
Nutrition's Role in Genetic Disorders
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Stress and Genetic Predispositions
Stress and Genetic Predispositions
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Housing Conditions and Poultry Health
Housing Conditions and Poultry Health
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Practical Solutions for Housing Issues
Practical Solutions for Housing Issues
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Bateman's Principle
Bateman's Principle
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Porcine Stress Syndrome (PSS)
Porcine Stress Syndrome (PSS)
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Autosomal Recessive Disorder
Autosomal Recessive Disorder
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Ryanodine Receptor
Ryanodine Receptor
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Single Gene Disorders
Single Gene Disorders
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Autosomal Dominant Disorder
Autosomal Dominant Disorder
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X-linked Disorder
X-linked Disorder
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Multifactorial Disorders
Multifactorial Disorders
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Genetic Predisposition
Genetic Predisposition
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Breeding and Selection for Single Gene Disorders
Breeding and Selection for Single Gene Disorders
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Breeding and Selection for Multifactorial Disorders
Breeding and Selection for Multifactorial Disorders
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Study Notes
Selection and Breeding Systems
- Animal breeding aims to improve livestock genetic makeup, enhancing productivity, disease resistance, and overall quality.
- This process heavily relies on selection and breeding systems.
Animal Breeding
- The goal is to improve the genetic makeup of livestock populations.
- This process is vital for enhancing various traits, including productivity, disease resistance, and overall quality.
Selection
- Selection is the act of choosing individuals to become parents for the next generation.
- It ensures desirable genes are passed on.
Selection Methods
- Individual Selection: Focuses on the individual animal's performance, most effective for traits with high heritability.
- Family Selection: Considers the average performance of a family, useful for traits with low heritability.
- Pedigree Selection: Choosing breeding animals based on their ancestors' performance.
- Progeny Testing: Evaluates an individual's breeding value based on its offspring's performance; especially helpful for traits observed after breeding or those restricted by sex.
Breeding Systems
- Breeding systems involve mating animals to achieve specific genetic outcomes.
- Example breeding systems include: outbreeding (outcrossing and crossbreeding), inbreeding, and species hybridization.
Outbreeding
- Animals that are not closely related are bred.
- Outcrossing: Mating animals that aren't closely related within the same breed.
- Crossbreeding: Mating animals from different breeds; can exploit heterosis (hybrid vigor).
Inbreeding
- Involves mating closely related animals.
- Increases homozygosity (having identical alleles) of the population.
- Often leads to inbreeding depression (reduced fitness).
Species Hybridization
- Different species interbreed.
- Results in hybrid offspring.
- Can lead to new traits, adaptations, and in some cases, new species.
Genetic Control of Farm Animal Traits and Inherited Disorders
Phenotypic Traits
- Qualitative: Classical Mendelian traits under strong genetic control, little environmental influence. Examples include form, structures, antigens, and antibodies.
- Quantitative: Measurable traits strongly affected by both genetic and environmental factors. Examples include milk production, meat yield, height, and weight.
Management and Control of Inherited Diseases
- Genetic Screening and Breeding Management:
- Screening
- Selective Breeding
- Early Diagnosis and Identification of At-Risk Animals:
- Health Monitoring
- Management of Carrier Animals
- Medical Management and Disease Control:
- Vaccination
- Medication
- Regular Monitoring and Health Tracking:
- Routine Health Checks
- Record Keeping
Inherited Disorders in Farm Animals
- Widespread use of artificial insemination and international semen trading spreads undesirable genes.
- Most common inheritance pattern for genetic diseases is autosomal recessive.
Autosomal Recessive Inheritance
- An individual must inherit two copies of a defective gene (one from each parent) to express the disorder.
- Specific examples like Bovine Brachyspina Syndrome (BBS), Bovine Leukocyte Adhesion Deficiency (BLAD), and Porcine Stress Syndrome (PSS) are highlighted.
Control of Single Gene and Multifactorial Disorders by Selection and Breeding
Single Gene (Mendelian) Disorders
- Mutations in a single gene create these disorders, with diverse inheritance patterns:
- Autosomal Dominant: Mutation in one gene copy causes the disorder.
- Autosomal Recessive: Both gene copies must be mutated for the disorder to appear.
- X-Linked: Disorders linked to mutations on the X chromosome.
Breeding and Selection for Single-Gene Disorders
- Effective breeding programs are facilitated by genetic testing allowing breeders to:
- Identify carriers
- Avoid affected individuals
- Use genetic testing as a preventative tool
Multifactorial Disorders
- Disorders influenced by multiple genes and environmental factors.
- Specific example disorders mentioned include diabetes, heart disease, and cleft palate.
Breeding and Selection for Multifactorial Disorders
- Breeders aim to reduce the risk by:
- Selecting individuals with fewer risk alleles.
- In the absence of precise genetic markers, selecting based on observable traits or health outcomes, and
- Managing environmental factors affecting animals.
Non-genetic (Environmental) Control of Inherited Disorders
Environmental Factors
- Environmental factors influence whether a genetically predisposed condition is expressed, including factors like nutrition, housing, and management practices.
1. Nutrition
- Balanced diets are essential for optimal growth and health.
- Poor nutrition can induce previously dormant genetic disorders.
- Examples include nutritional disorders in livestock.
2. Management Practices
- Stress can exacerbate genetic predispositions.
- Stress lowers the animal's immune response.
- Management practices (e.g., housing conditions, handling techniques) should minimize stress.
Types of Mating Systems In Sexual Animals
- Monogamy: Single male with a single female; both contribute to defense and offspring care.
- Polygamy: One male breeds with multiple females.
- Resource defense
- Male dominance
- Harems
- Lek
- Promiscuity: Both males and females have multiple mates.
- Polyandry: One female breeds with multiple males; multiple males often contribute to care and provisioning.
- Polygynandry: Multiple females and males mate with each other; males may care for several females' offspring.
Selection of Phenotypes
- Phenotypes are observable traits resulting from gene-environment interactions.
- Physical characteristics and other observable traits are included in this process.
Phenotypic Selection
- Individuals with different traits differ in survival/reproduction.
- Phenotypic selection is nonrandom differential survival/reproduction of individuals.
Types of Selection
- Stabilizing selection: Favors an average phenotype. Selection against extreme phenotypes.
- Directional selection: Phenotypes at one end of the spectrum are favored. Selection caused by environment changes.
- Diversifying selection: Phenotypes at opposite extremes are favored. Intermediate forms have lower fitness.
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