Livestock Breeding Systems Overview

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Questions and Answers

What is the main purpose of selection and breeding systems in livestock populations?

To improve genetic makeup for enhanced productivity, disease resistance, and overall quality.

Differentiate between individual selection and family selection.

Individual selection focuses on an animal's specific performance traits, while family selection considers the average performance of an entire family.

Explain the role of progeny testing in selection methods.

Progeny testing evaluates an individual's breeding value based on the performance of its offspring.

What is the potential downside of inbreeding in livestock populations?

<p>Inbreeding can lead to increased homozygosity and inbreeding depression.</p> Signup and view all the answers

How does outcrossing differ from crossbreeding?

<p>Outcrossing involves mating animals that are not closely related within the same breed, while crossbreeding involves mating animals from different breeds.</p> Signup and view all the answers

What is the significance of differentiating between qualitative and quantitative traits in genetic control?

<p>Qualitative traits are classical Mendelian traits under genetic control, while quantitative traits are measurable and economically important.</p> Signup and view all the answers

What role does environmental management play in the context of breeding animals?

<p>Environmental management is crucial for creating optimal conditions that influence the health and traits of the animals, impacting their genetic expression.</p> Signup and view all the answers

How can poor nutrition lead to the expression of dormant genetic disorders in animals?

<p>Poor nutrition can activate genetic disorders that remain dormant in well-nourished animals, causing health issues.</p> Signup and view all the answers

Explain the significance of housing conditions in poultry regarding their health outcomes.

<p>Housing conditions significantly impact poultry health outcomes by affecting respiratory systems, especially when overcrowding and poor ventilation are present.</p> Signup and view all the answers

What are some practical solutions to mitigate stress in pigs that might lead to inherited conditions?

<p>Practical solutions include providing adequate space, gentle handling during transportation, and gradual dietary changes.</p> Signup and view all the answers

What did Angus John Bateman's research on Drosophila melanogaster contribute to the field of phenotypic selection?

<p>Bateman's research provided insights into the relationship between genotypes and phenotypes, influencing methods of animal breeding.</p> Signup and view all the answers

Identify and describe the impact of management practices on influencing genetic predispositions in animals.

<p>Management practices can exacerbate genetic predispositions by increasing stress and lowering immune responses, leading to more severe symptoms of inherited conditions.</p> Signup and view all the answers

What is the significance of autosomal recessive inheritance in the context of inherited disorders in farm animals?

<p>It highlights that an individual must inherit two defective gene copies to express genetic disorders, making breeding decisions critical in management.</p> Signup and view all the answers

Explain how artificial insemination (AI) exacerbates the spread of undesirable genes in livestock.

<p>AI and international semen trading allow for rapid genetic dissemination, increasing the likelihood of undesirable genetic traits entering the population.</p> Signup and view all the answers

Describe the characteristics and outcomes associated with Bovine Brachyspina Syndrome (BBS).

<p>BBS is characterized by a shortened spine leading to developmental abnormalities, often resulting in stillbirth or death shortly after birth.</p> Signup and view all the answers

What role does genetic screening play in managing inherited diseases in farm animals?

<p>Genetic screening helps identify at-risk animals, allowing for selective breeding strategies to mitigate the spread of inherited disorders.</p> Signup and view all the answers

Identify key management strategies to prevent the dominance of autosomal recessive disorders in livestock populations.

<p>Key strategies include selective breeding of carrier animals, regular health checks, and maintaining detailed records of genetic traits.</p> Signup and view all the answers

What are the clinical signs of Bovine Leukocyte Adhesion Deficiency (BLAD) in affected cattle?

<p>Affected cattle show signs of recurrent bacterial infections, delayed wound healing, stunted growth, and persistent marked neutrophilia.</p> Signup and view all the answers

Discuss how vaccination and health monitoring contribute to the management of inherited diseases in farm animals.

<p>Vaccination helps prevent secondary infections while regular health monitoring enables the early detection of inherited disorders.</p> Signup and view all the answers

How can record keeping assist in the identification of at-risk animals in the context of inherited diseases?

<p>Record keeping allows for tracking genetic traits and health history, aiding in identifying at-risk animals for targeted management strategies.</p> Signup and view all the answers

What is the primary cause of Porcine Stress Syndrome (PSS)?

<p>A defective ryanodine receptor leads to an excess calcium influx.</p> Signup and view all the answers

Describe the inheritance pattern of autosomal recessive disorders.

<p>Both copies of the gene must be mutated for the disorder to manifest.</p> Signup and view all the answers

How do genetic testing and selection help prevent single gene disorders in breeding programs?

<p>Genetic testing identifies carriers and allows breeders to avoid affected individuals.</p> Signup and view all the answers

What distinguishes multifactorial disorders from single-gene disorders?

<p>Multifactorial disorders are influenced by multiple genes and environmental factors.</p> Signup and view all the answers

Give an example of a multifactorial disorder and mention its contributing factors.

<p>Diabetes is an example, influenced by genetic predisposition and factors such as diet and lifestyle.</p> Signup and view all the answers

What is the significance of the X chromosome in X-linked disorders?

<p>X-linked disorders affect males more severely due to their single X chromosome.</p> Signup and view all the answers

What role do environmental factors play in multifactorial disorders?

<p>Environmental factors can exacerbate or mitigate genetic predispositions.</p> Signup and view all the answers

How do breeders aim to minimize the risk of multifactorial disorders?

<p>Breeders select individuals with fewer risk alleles for the disorder.</p> Signup and view all the answers

What is the inheritance pattern observed in Huntington's Disease?

<p>Huntington's Disease follows an autosomal dominant inheritance pattern.</p> Signup and view all the answers

In the context of breeding, why is the selection of carriers important?

<p>Identifying carriers allows for strategic mating to prevent the expression of genetic disorders.</p> Signup and view all the answers

Flashcards

Animal Breeding

The process of improving livestock genetics to boost productivity, disease resistance, and overall quality. It heavily relies on selection and breeding systems.

Selection

Choosing individuals to become parents and pass their genes to the next generation.

Individual Selection

Focusing on an animal's individual performance for specific traits. Most effective for traits with high heritability.

Family Selection

Considering the average performance of a family and selecting entire families based on their overall merit. Useful for traits with low heritability.

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Outbreeding

Mating animals that aren't closely related but are within the same breed. It aims to maintain genetic diversity.

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Crossbreeding

Mating animals from different breeds to exploit heterosis (hybrid vigor). This often leads to stronger offspring.

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Autosomal Recessive Inheritance

A type of inheritance where an individual must receive two copies of a defective gene, one from each parent, to express the disorder.

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Bovine Brachyspina Syndrome (BBS)

A genetic disorder in cattle, primarily affecting Holstein cows, characterized by a shortened spine, leading to developmental abnormalities and often death shortly after birth.

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Bovine Leukocyte Adhesion Deficiency (BLAD)

An autosomal recessive disease in Holstein cattle, causing recurrent bacterial infections, slow wound healing, stunted growth, and an abnormally high number of white blood cells.

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Genetic Screening

Testing animals to identify carriers of genetic disorders, helping to prevent the spread of these disorders within a population.

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Selective Breeding

Choosing animals with desirable traits to breed, reducing the occurrence of genetic disorders.

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Early Diagnosis and Identification of At-Risk Animals

Identifying animals that have genetic disorders or are carrying genes for those disorders early on.

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Management and Disease Control

Implementing strategies to manage genetic disorders in livestock, such as isolating affected animals or treating them.

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Regular Monitoring and Health Tracking

Keeping records of animal health and genetic status to identify trends and potential problems related to genetic disorders.

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Environmental Control of Inherited Disorders

Managing environmental factors to minimize the impact of genetic predispositions on animal health and performance. This includes optimizing nutrition, housing, and management practices to create a more favorable environment for animals.

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Nutrition's Role in Genetic Disorders

A well-balanced diet can help prevent dormant genetic disorders from becoming active. Inadequate nutrition can trigger the expression of otherwise dormant genetic conditions.

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Stress and Genetic Predispositions

Stress can worsen genetic predispositions by lowering an animal's immune response and increasing susceptibility to inherited conditions.

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Housing Conditions and Poultry Health

Poor housing conditions, like high stocking densities and poor ventilation, can exacerbate respiratory problems in poultry with a genetic predisposition to weak respiratory systems.

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Practical Solutions for Housing Issues

Providing more space, proper airflow, and regular cleaning and disinfection can improve housing conditions and minimize the impact of genetic predispositions on poultry health.

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Bateman's Principle

This principle, proposed by Angus John Bateman in 1948, suggests that the reproductive success of males is more strongly influenced by the number of mates they acquire than by the number of offspring they produce per mate, while females are more limited by their ability to produce offspring.

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Porcine Stress Syndrome (PSS)

A genetic disorder in pigs where stress triggers catastrophic muscle contractions leading to death.

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Autosomal Recessive Disorder

A disorder caused by two copies of a mutated gene, one from each parent.

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Ryanodine Receptor

A protein in muscle cells responsible for controlling calcium release and muscle contraction.

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Single Gene Disorders

Disorders caused by mutations in a single gene, following simple inheritance patterns.

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Autosomal Dominant Disorder

A disorder caused by one copy of a mutated gene, the dominant allele.

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X-linked Disorder

A disorder caused by a mutation on the X chromosome, affecting males more severely than females.

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Multifactorial Disorders

Disorders influenced by multiple genes and environmental factors.

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Genetic Predisposition

The inherent risk of developing a disorder based on an individual's genes.

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Breeding and Selection for Single Gene Disorders

Strategies used to control single gene disorders through genetic testing to identify carriers and avoid affected individuals.

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Breeding and Selection for Multifactorial Disorders

Strategies used to control multifactorial disorders by selecting individuals with fewer risk alleles for the disorder.

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Study Notes

Selection and Breeding Systems

  • Animal breeding aims to improve livestock genetic makeup, enhancing productivity, disease resistance, and overall quality.
  • This process heavily relies on selection and breeding systems.

Animal Breeding

  • The goal is to improve the genetic makeup of livestock populations.
  • This process is vital for enhancing various traits, including productivity, disease resistance, and overall quality.

Selection

  • Selection is the act of choosing individuals to become parents for the next generation.
  • It ensures desirable genes are passed on.

Selection Methods

  • Individual Selection: Focuses on the individual animal's performance, most effective for traits with high heritability.
  • Family Selection: Considers the average performance of a family, useful for traits with low heritability.
  • Pedigree Selection: Choosing breeding animals based on their ancestors' performance.
  • Progeny Testing: Evaluates an individual's breeding value based on its offspring's performance; especially helpful for traits observed after breeding or those restricted by sex.

Breeding Systems

  • Breeding systems involve mating animals to achieve specific genetic outcomes.
  • Example breeding systems include: outbreeding (outcrossing and crossbreeding), inbreeding, and species hybridization.

Outbreeding

  • Animals that are not closely related are bred.
  • Outcrossing: Mating animals that aren't closely related within the same breed.
  • Crossbreeding: Mating animals from different breeds; can exploit heterosis (hybrid vigor).

Inbreeding

  • Involves mating closely related animals.
  • Increases homozygosity (having identical alleles) of the population.
  • Often leads to inbreeding depression (reduced fitness).

Species Hybridization

  • Different species interbreed.
  • Results in hybrid offspring.
  • Can lead to new traits, adaptations, and in some cases, new species.

Genetic Control of Farm Animal Traits and Inherited Disorders

Phenotypic Traits

  • Qualitative: Classical Mendelian traits under strong genetic control, little environmental influence. Examples include form, structures, antigens, and antibodies.
  • Quantitative: Measurable traits strongly affected by both genetic and environmental factors. Examples include milk production, meat yield, height, and weight.

Management and Control of Inherited Diseases

  • Genetic Screening and Breeding Management:
    • Screening
    • Selective Breeding
  • Early Diagnosis and Identification of At-Risk Animals:
    • Health Monitoring
    • Management of Carrier Animals
  • Medical Management and Disease Control:
    • Vaccination
    • Medication
  • Regular Monitoring and Health Tracking:
    • Routine Health Checks
    • Record Keeping

Inherited Disorders in Farm Animals

  • Widespread use of artificial insemination and international semen trading spreads undesirable genes.
  • Most common inheritance pattern for genetic diseases is autosomal recessive.

Autosomal Recessive Inheritance

  • An individual must inherit two copies of a defective gene (one from each parent) to express the disorder.
  • Specific examples like Bovine Brachyspina Syndrome (BBS), Bovine Leukocyte Adhesion Deficiency (BLAD), and Porcine Stress Syndrome (PSS) are highlighted.

Control of Single Gene and Multifactorial Disorders by Selection and Breeding

Single Gene (Mendelian) Disorders

  • Mutations in a single gene create these disorders, with diverse inheritance patterns:
    • Autosomal Dominant: Mutation in one gene copy causes the disorder.
    • Autosomal Recessive: Both gene copies must be mutated for the disorder to appear.
    • X-Linked: Disorders linked to mutations on the X chromosome.

Breeding and Selection for Single-Gene Disorders

  • Effective breeding programs are facilitated by genetic testing allowing breeders to:
    • Identify carriers
    • Avoid affected individuals
    • Use genetic testing as a preventative tool

Multifactorial Disorders

  • Disorders influenced by multiple genes and environmental factors.
  • Specific example disorders mentioned include diabetes, heart disease, and cleft palate.

Breeding and Selection for Multifactorial Disorders

  • Breeders aim to reduce the risk by:
    • Selecting individuals with fewer risk alleles.
    • In the absence of precise genetic markers, selecting based on observable traits or health outcomes, and
    • Managing environmental factors affecting animals.

Non-genetic (Environmental) Control of Inherited Disorders

Environmental Factors

  • Environmental factors influence whether a genetically predisposed condition is expressed, including factors like nutrition, housing, and management practices.

1. Nutrition

  • Balanced diets are essential for optimal growth and health.
  • Poor nutrition can induce previously dormant genetic disorders.
  • Examples include nutritional disorders in livestock.

2. Management Practices

  • Stress can exacerbate genetic predispositions.
  • Stress lowers the animal's immune response.
  • Management practices (e.g., housing conditions, handling techniques) should minimize stress.

Types of Mating Systems In Sexual Animals

  • Monogamy: Single male with a single female; both contribute to defense and offspring care.
  • Polygamy: One male breeds with multiple females.
    • Resource defense
    • Male dominance
    • Harems
    • Lek
  • Promiscuity: Both males and females have multiple mates.
  • Polyandry: One female breeds with multiple males; multiple males often contribute to care and provisioning.
  • Polygynandry: Multiple females and males mate with each other; males may care for several females' offspring.

Selection of Phenotypes

  • Phenotypes are observable traits resulting from gene-environment interactions.
  • Physical characteristics and other observable traits are included in this process.

Phenotypic Selection

  • Individuals with different traits differ in survival/reproduction.
  • Phenotypic selection is nonrandom differential survival/reproduction of individuals.

Types of Selection

  • Stabilizing selection: Favors an average phenotype. Selection against extreme phenotypes.
  • Directional selection: Phenotypes at one end of the spectrum are favored. Selection caused by environment changes.
  • Diversifying selection: Phenotypes at opposite extremes are favored. Intermediate forms have lower fitness.

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