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Lipoprotein Metabolism and Cardiovascular Disease

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Lipoprotein Metabolism and Cardiovascular Disease

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Questions and Answers

What is the primary function of thyroid hormone in triacylglycerol metabolism?

Regulating the synthesis of fatty acids

Enhancing the storage of triacylglycerols in adipose tissue

Inhibiting the breakdown of lipids in the liver

Stimulating the oxidation of cholesterol and its conversion to bile acids (correct)

Which of the following is a characteristic of fatty liver?

Increased breakdown of fatty acids

Accumulation of phospholipids in the liver

Decreased synthesis of cholesterol

Extensive accumulation of lipids, mostly as triacylglycerols (correct)

What is the primary source of acetyl CoA for cholesterol synthesis?

Pyruvate dehydrogenase reaction (correct)

Fatty acid β-oxidation

Aerobic glycolysis

Ketogenic amino acid breakdown

Which of the following is NOT a fate of acetyl CoA?

Protein synthesis Signup and view all the answers

What is the result of a mutation in the receptor gene leading to defective synthesis of the receptor and/or defective binding to LDLs?

Familial hypercholesterolemia Signup and view all the answers

What is the primary role of adipose tissue in lipid metabolism?

Storing triacylglycerols and releasing fatty acids during fasting Signup and view all the answers

What is the fate of acetyl CoA in the liver during fasting?

Ketone bodies synthesis Signup and view all the answers

Which of the following is a dietary factor that contributes to hypercholesterolemia?

High intake of saturated fat and cholesterol Signup and view all the answers

What is the primary source of acetyl CoA for fatty acid synthesis?

Citrate lyase reaction Signup and view all the answers

What is the result of obstructive jaundice on lipid metabolism?

Blocked pathway for excretion of cholesterol and bile acids Signup and view all the answers