Lipoprotein Metabolism and Cardiovascular Disease
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Questions and Answers

What is the primary function of thyroid hormone in triacylglycerol metabolism?

  • Regulating the synthesis of fatty acids
  • Enhancing the storage of triacylglycerols in adipose tissue
  • Inhibiting the breakdown of lipids in the liver
  • Stimulating the oxidation of cholesterol and its conversion to bile acids (correct)

Which of the following is a characteristic of fatty liver?

  • Increased breakdown of fatty acids
  • Accumulation of phospholipids in the liver
  • Decreased synthesis of cholesterol
  • Extensive accumulation of lipids, mostly as triacylglycerols (correct)

What is the primary source of acetyl CoA for cholesterol synthesis?

  • Pyruvate dehydrogenase reaction (correct)
  • Fatty acid β-oxidation
  • Aerobic glycolysis
  • Ketogenic amino acid breakdown

Which of the following is NOT a fate of acetyl CoA?

<p>Protein synthesis (C)</p> Signup and view all the answers

What is the result of a mutation in the receptor gene leading to defective synthesis of the receptor and/or defective binding to LDLs?

<p>Familial hypercholesterolemia (D)</p> Signup and view all the answers

What is the primary role of adipose tissue in lipid metabolism?

<p>Storing triacylglycerols and releasing fatty acids during fasting (B)</p> Signup and view all the answers

What is the fate of acetyl CoA in the liver during fasting?

<p>Ketone bodies synthesis (B)</p> Signup and view all the answers

Which of the following is a dietary factor that contributes to hypercholesterolemia?

<p>High intake of saturated fat and cholesterol (C)</p> Signup and view all the answers

What is the primary source of acetyl CoA for fatty acid synthesis?

<p>Citrate lyase reaction (C)</p> Signup and view all the answers

What is the result of obstructive jaundice on lipid metabolism?

<p>Blocked pathway for excretion of cholesterol and bile acids (B)</p> Signup and view all the answers

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