Lipids Overview and Fatty Acid Structure

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Questions and Answers

What property do amphipathic lipids possess?

  • They are only hydrophobic.
  • They are entirely soluble in water.
  • They have both hydrophobic and hydrophilic properties. (correct)
  • They are exclusively polar molecules.

Which type of fatty acid contains at least one double bond?

  • Trans fatty acids
  • Hydrocarbon fatty acids
  • Saturated fatty acids
  • Unsaturated fatty acids (correct)

What is one of the primary functions of lipids in the body?

  • Acting only as structural components of cells
  • Facilitating digestion of carbohydrates
  • Producing nucleic acids
  • Serving as a major source of energy (correct)

Which of the following fatty acids is known for its kinking structure due to double bonds?

<p>Oleic acid (C)</p> Signup and view all the answers

What distinguishes triacylglycerols (TAGs) from other types of lipids?

<p>They are composed of glycerol and three fatty acids. (A)</p> Signup and view all the answers

What is the IUPAC nomenclature primarily concerned with in fatty acids?

<p>The length of the carbon chain and positions of double bonds (D)</p> Signup and view all the answers

How is the carboxyl nomenclature expressed?

<p>With the number of carbon atoms, double bonds, and their positions (C)</p> Signup and view all the answers

Which abbreviation refers to the position of double bonds counting from the methyl carbon?

<p>Omega (D)</p> Signup and view all the answers

What percentage of lipids in a high-fat meal consists of triacylglycerol (TAG)?

<p>90% (D)</p> Signup and view all the answers

Where does the digestion of lipids primarily begin?

<p>In the mouth with saliva (A)</p> Signup and view all the answers

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Study Notes

Lipids: An Overview

  • Lipids are a diverse group of non-polar (hydrophobic) or amphipathic (both hydrophobic and hydrophilic) organic molecules.
  • Key functions include energy storage (triacylglycerols - TAGs), membrane components (phospholipids, glycolipids, cholesterol), hormone production (steroid hormones, eicosanoids), and solubilization of non-polar substances (fat-soluble vitamins).
  • Types in humans: fatty acids, TAGs, phospholipids (glycerophospholipids, sphingolipids), eicosanoids, steroids, complex lipids (lipoproteins, glycolipids), and fat-soluble vitamins.

Fatty Acid Structure and Nomenclature

  • Composed of a hydrophilic carboxyl group and a hydrophobic hydrocarbon chain.
  • Most common chain lengths are 16, 18, and 20 carbons.
  • Unsaturated fatty acids contain double bonds, creating kinks; saturated fatty acids lack double bonds.
  • Four naming systems:
    • Trivial: based on source (e.g., palmitic acid from palm oil).
    • IUPAC: Greek-derived, indicating chain length and double bond positions (e.g., 9,12,15-octadecenoic acid).
    • Carboxyl: specifies carbon number, number of double bonds, and their positions (e.g., 18:3 Δ9,12,15).
    • Omega: indicates carbon number, number of double bonds, and position of the closest double bond to the methyl (omega) carbon (e.g., 18:3 ω-3).

Fatty Acid Chain Length Classification

  • Short-chain (<6 carbons)
  • Medium-chain (6-12 carbons)
  • Long-chain (13-20 carbons)
  • Very long-chain (≥21 carbons) (Note: exact numbers may vary)

Lipid Digestion and Absorption

  • Dietary lipids are primarily TAGs (90%), with cholesterol, cholesterol esters, phospholipids, and free fatty acids making up the remaining 10%.
  • Linoleic and linolenic acids are essential fatty acids – the body cannot synthesize them.
  • Lipids' water insolubility leads to lipid droplets in chyme.
  • Digestion begins in the mouth and stomach via acid-stable lipases (lingual and gastric lipases), primarily targeting TAGs with short and medium-chain fatty acids.

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