5 Questions
What is the final product formed through the reactions catalyzed by the seven enzymes of fatty acid synthase complex?
Palmitate
Which molecules combine with a cysteine -SH group in the fatty acid synthase complex?
Acetyl-CoA and Malonyl-CoA
Which functional group do Acetyl-CoA and Malonyl-CoA combine with on the 4'-phosphopantetheine?
Sulfhydryl (-SH)
Which step includes the overall synthesis of palmitate from acetyl-CoA and malonyl-CoA?
Step II
Which enzymes are involved in catalyzing the reactions in the fatty acid synthase complex?
Seven enzyme components
Study Notes
Fatty Acid Synthesis
- Acetyl-CoA and Malonyl-CoA combine with a cysteine -SH group and adjacent -SH group to form a complex.
- This complex is catalyzed by the fatty acid synthase complex, which is composed of seven enzyme components.
- The reaction ultimately forms palmitate.
Palmitate Synthesis Equation
- The overall equation for the synthesis of palmitate from acetyl-CoA and malonyl-CoA is:
Functional Division
- Lipid metabolism can be functionally divided into different stages or processes.
Phosphopantetheine
- 4'-Phosphopantetheine plays a role in lipid metabolism.
Coenzyme A Components
- Coenzyme A is composed of three key components: pantothenate (K), thiol (Th), and cysteine (Cys).
This quiz covers lipid metabolism lectures 4-9, including the synthesis of palmitate from acetyl-CoA and malonyl-CoA, fatty acid synthase complex, and functional division.
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