Lipid Lowering Compounds and Metabolism Quiz

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Questions and Answers

Which enzyme is responsible for the hydrolysis of triglycerides in chylomicrons and VLDL?

  • Hepatic lipase
  • Lipoprotein lipase (LPL) (correct)
  • HMG-CoA reductase
  • Cholesteryl ester transfer protein (CETP)

Which lipoprotein is taken up by the liver through interaction with the LDL receptor?

  • LDL (correct)
  • VLDL
  • IDL
  • HDL

Which enzyme catalyzes the conversion of free cholesterol to cholesterol esters in HDL particles?

  • Hepatic lipase
  • Lipoprotein lipase (LPL)
  • Lecithin cholesterol acyl transferase (LCAT) (correct)
  • HMG-CoA reductase

Which pathway is responsible for the biosynthesis of cholesterol and isoprenoids?

<p>The Mevalonate Pathway (D)</p> Signup and view all the answers

Which compound is responsible for the transfer of cholesteryl esters from HDL to VLDL and LDL particles?

<p>Cholesteryl ester transfer protein (CETP) (D)</p> Signup and view all the answers

Which enzyme is responsible for the hydrolysis of triglycerides in chylomicron remnants in the adipose tissue?

<p>Hepatic lipase (C)</p> Signup and view all the answers

Which lipoprotein is formed in the endogenous pathway and delivers cholesterol and triglycerides to peripheral tissues?

<p>VLDL (A)</p> Signup and view all the answers

Which compound is responsible for the transfer of cholesterol esters from LDL to HDL particles?

<p>Cholesteryl ester transfer protein (D)</p> Signup and view all the answers

Which pathway is responsible for the uptake of cholesterol from peripheral tissues and its transport back to the liver?

<p>Reverse Cholesterol Transport Pathway (C)</p> Signup and view all the answers

Which compound is a precursor in the biosynthesis of cholesterol and isoprenoids?

<p>Isopentenyl pyrophosphate (C)</p> Signup and view all the answers

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