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Questions and Answers
Which type of lipids are major dietary components?
Which type of lipids are major dietary components?
What role does lingual lipase play in lipid digestion?
What role does lingual lipase play in lipid digestion?
What is the main function of gastric lipase?
What is the main function of gastric lipase?
How does emulsification assist in lipid digestion?
How does emulsification assist in lipid digestion?
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What percentage of triglycerides is digested in the stomach?
What percentage of triglycerides is digested in the stomach?
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Which organ produces bile and stores it in the gallbladder?
Which organ produces bile and stores it in the gallbladder?
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What is formed when triglycerides are broken down in the small intestine?
What is formed when triglycerides are broken down in the small intestine?
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What role does carbohydrate metabolism play in lipid metabolism?
What role does carbohydrate metabolism play in lipid metabolism?
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What are the primary products of fat digestion that need to enter circulation?
What are the primary products of fat digestion that need to enter circulation?
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What structure do bile salts form to aid in lipid absorption?
What structure do bile salts form to aid in lipid absorption?
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Which component is directly absorbed into the bloodstream without the need for transport vehicles?
Which component is directly absorbed into the bloodstream without the need for transport vehicles?
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Where are chylomicrons transported after being formed inside intestinal cells?
Where are chylomicrons transported after being formed inside intestinal cells?
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What is the function of lipase enzymes in infants?
What is the function of lipase enzymes in infants?
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What energy conversion process is referred to as lipolysis?
What energy conversion process is referred to as lipolysis?
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How does breast milk contribute to an infant's energy needs?
How does breast milk contribute to an infant's energy needs?
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What is the result of one triglyceride molecule undergoing lipolysis?
What is the result of one triglyceride molecule undergoing lipolysis?
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Study Notes
Lipid Digestion and Absorption
- Lipids are ingested as food or synthesized from carbohydrates.
- Lipid metabolism involves oxidizing fatty acids to generate energy or synthesize new lipids.
- The major dietary lipids are triglycerides, cholesterol, and phospholipids.
- Filipinos consume an average of 56.56 grams of lipids per day.
Lipid Digestion in the Mouth
- Chewing breaks down food into smaller particles, mixing it with saliva.
- Lingual lipase, produced by tongue cells, begins the breakdown of lipids.
- Lingual lipase acts on short-chain triglycerides.
- Its optimal pH range is 2.5-5, so it works in the stomach.
Lipid Digestion in the Stomach
- Up to 30% of triglycerides are digested in the stomach.
- Two lipases (lingual and gastric) play a minor role in fat digestion.
- Gastric lipase is acid-stable and functions best at a pH of about 5.4.
- It acts on short-chain triglycerides (SCT).
- Stomach acids and churning are important for breaking down fats more effectively.
Lipid Digestion in the Small Intestine
- Most dietary lipids are undigested and form droplets in the small intestine.
- Bile, from the liver and stored in the gallbladder, is released into the duodenum to aid lipid digestion.
- Emulsification by bile increases the surface area, allowing digestive enzymes to act effectively.
- Pancreatic lipases help break down lipids into fatty acids, monoglycerides.
- Micelles transport the absorbed products to the intestinal cells.
Lipid Absorption in the Small Intestine
- Products of fat digestion (fatty acids, monoglycerides, glycerol, cholesterol, fat-soluble vitamins) enter the bloodstream.
- Bile salts help form micelles, allowing these products to cross the intestinal cells' membrane.
- Bile salts get reused for further emulsification.
- Short and medium-chain fatty acids and glycerol are absorbed directly into capillaries.
- Long-chain fatty acids and monoglycerides combine with proteins forming chylomicrons.
- Chylomicrons enter lymph vessels and eventually enter the circulatory system.
- Lipids can be stored in fat cells or go to the liver.
Special Adaptations in Infants
- Breast milk, similar to whole cow's milk, contains around 4% fat.
- Infants have plenty of lingual and gastric lipases from birth.
- Breast milk contains lipase enzymes that activate in the infant's small intestine.
- Bile and pancreatic enzymes are less developed in infants and become more significant for lipid digestion in older children and adults.
Lipolysis
- Lipolysis breaks down fat stores for energy production.
- This process occurs in the cytoplasm of adipocytes (fat cells).
- Fatty acids are oxidized into acetyl CoA.
- Acetyl CoA is used for energy generation in the Krebs cycle.
Lipogenesis
- Lipogenesis creates fats from acetyl CoA.
- It also happens in the cytoplasm of adipocytes and hepatocytes.
- When carbohydrates are consumed in excess, they are converted into fat.
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Description
Test your knowledge on lipid digestion and absorption, including the role of enzymes and the digestion process in the mouth and stomach. Discover how dietary lipids are metabolized and the significance of various lipases. Perfect for students studying nutrition or biochemistry.