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Limb Development and Specification Quiz
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Limb Development and Specification Quiz

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@FascinatingBowenite4271

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Questions and Answers

Which signaling pathway is involved in limb specification and outgrowth?

  • Fgf signaling
  • Wnt signaling (correct)
  • Shh signaling
  • BMP signaling
  • Which structure is responsible for proximal-distal patterning in limb development?

  • Zone of polarizing activity (ZPA)
  • Somites
  • Apical ectodermal ridge (AER) (correct)
  • Lateral plate mesoderm
  • Which signaling molecule is associated with dorsal-ventral patterning in limb development?

  • Bmp
  • Wnt7a (correct)
  • Engrailed-1
  • Gremlin
  • Which transcription factor is responsible for the expression in osteoblasts in all skeletal elements?

    <p>Osterix (Osx)</p> Signup and view all the answers

    What is the consequence of inactivation of Atf4 in mice?

    <p>All of the above</p> Signup and view all the answers

    Which zinc finger–containing transcription factor is expressed in osteoblasts in all skeletal elements?

    <p>Osterix (Osx)</p> Signup and view all the answers

    Which transcription factor is associated with chondrocytes and responsible for cartilage template of future bone?

    <p>SOX9</p> Signup and view all the answers

    Which developmental signals are involved in osteoblast differentiation?

    <p>BMP2/7</p> Signup and view all the answers

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