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Questions and Answers
Which signaling pathway is involved in limb specification and outgrowth?
Which signaling pathway is involved in limb specification and outgrowth?
- Fgf signaling
- Wnt signaling (correct)
- Shh signaling
- BMP signaling
Which structure is responsible for proximal-distal patterning in limb development?
Which structure is responsible for proximal-distal patterning in limb development?
- Zone of polarizing activity (ZPA)
- Somites
- Apical ectodermal ridge (AER) (correct)
- Lateral plate mesoderm
Which signaling molecule is associated with dorsal-ventral patterning in limb development?
Which signaling molecule is associated with dorsal-ventral patterning in limb development?
- Bmp
- Wnt7a (correct)
- Engrailed-1
- Gremlin
Which transcription factor is responsible for the expression in osteoblasts in all skeletal elements?
Which transcription factor is responsible for the expression in osteoblasts in all skeletal elements?
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What is the consequence of inactivation of Atf4 in mice?
What is the consequence of inactivation of Atf4 in mice?
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Which zinc finger–containing transcription factor is expressed in osteoblasts in all skeletal elements?
Which zinc finger–containing transcription factor is expressed in osteoblasts in all skeletal elements?
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Which transcription factor is associated with chondrocytes and responsible for cartilage template of future bone?
Which transcription factor is associated with chondrocytes and responsible for cartilage template of future bone?
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Which developmental signals are involved in osteoblast differentiation?
Which developmental signals are involved in osteoblast differentiation?
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