Levothyroxine Pharmacology Flashcards
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Levothyroxine Pharmacology Flashcards

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Questions and Answers

What classification does Levothyroxine belong to?

  • Antidepressant
  • Anticoagulant
  • Thyroid hormones (correct)
  • Antibiotic
  • What are the therapeutic actions of Levothyroxine?

    Increases the metabolic rate of body tissues, increasing oxygen consumption, respiration, and heart rate; the rate of fat, protein, and carbohydrate metabolism; and growth and maturation.

    What decreases the absorption of thyroid hormones when taken together with Levothyroxine?

    Cholestyramine

    How is Levothyroxine metabolized and excreted?

    <p>Metabolized in the liver and excreted in bile.</p> Signup and view all the answers

    What are some contraindications for Levothyroxine?

    <p>All of the above</p> Signup and view all the answers

    What are some common adverse effects of Levothyroxine?

    <p>Tremors, headache, nervousness, palpitations, tachycardia, allergic skin reactions, anxiety, alopecia, diarrhea, nausea/vomiting.</p> Signup and view all the answers

    What nursing considerations should be taken when administering Levothyroxine?

    <p>Baseline ECG and thyroid function, take before breakfast, take with full glass of water.</p> Signup and view all the answers

    Study Notes

    Levothyroxine Overview

    • Levothyroxine is classified as a thyroid hormone used to treat various thyroid-related conditions.

    Therapeutic Actions and Indications

    • Increases metabolic rate, oxygen consumption, respiration, heart rate, and metabolism of fats, proteins, and carbohydrates.
    • Indicated for treating hypothyroidism, euthyroid goiters, thyroid cancer, thyrotoxicosis, and myxedema coma.

    Drug Interactions

    • Absorption can be decreased when taken with cholestyramine; should be taken 2 hours apart.
    • Dosing adjustments may be necessary for anticoagulants when taken concurrently.

    Pharmacokinetics

    • Administered orally; metabolized in the liver and excreted via bile.

    Contraindications and Cautions

    • Contraindicated in individuals with allergies to the drug, acute thyrotoxicosis, or acute myocardial infarction.
    • Use with caution in patients who are lactating or have hypoadrenal conditions such as Addison's disease.

    Adverse Effects

    • Possible side effects include tremors, headaches, nervousness, palpitations, tachycardia, allergic skin reactions, anxiety, alopecia, diarrhea, and nausea/vomiting.
    • Generally well-tolerated once the correct dosage is established.

    Nursing Considerations

    • Baseline assessments should include ECG and thyroid function tests.
    • Administer medication before breakfast with a full glass of water to help prevent esophageal stricture.

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    Description

    Explore the pharmacological aspects of Levothyroxine through these informative flashcards. Each card provides key classifications and therapeutic actions associated with this essential thyroid hormone. Perfect for students and healthcare professionals alike.

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