Levocetirizine Flashcards
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Questions and Answers

What is the brand name of Levocetirizine?

  • Claritin
  • Xyzal (correct)
  • Allegra
  • Zyrtec
  • What class of drug is Levocetirizine?

    Antihistamine

    What are the common FDA indications for Levocetirizine?

    Idiopathic urticaria, perennial, or seasonal allergic rhinitis

    What is the mechanism of action (MOA) of Levocetirizine?

    <p>Levocetirizine is a low-sedating, long-acting H1-receptor antagonist that inhibits histamine interaction with H1 receptors.</p> Signup and view all the answers

    Adjust Levocetirizine dosing when CrCl is _____ mL/min.

    <p>30-50</p> Signup and view all the answers

    For CrCl _____ mL/min, the dosage is 2.5 mg po twice per week.

    <p>10-29</p> Signup and view all the answers

    Study Notes

    Levocetirizine Overview

    • Brand Name: Xyzal
    • Drug Class: Antihistamine

    Indications

    • Commonly prescribed for idiopathic urticaria.
    • Effective for perennial allergic rhinitis.
    • Utilized for seasonal allergic rhinitis.

    Mechanism of Action

    • Enantiomer of cetirizine, classified as a low-sedating antihistamine.
    • Functions as a long-acting H1-receptor antagonist.
    • Metabolite of hydroxyzine.
    • Inhibits histamine’s interaction with H1 receptors, thereby halting the allergic response.

    Renal Dosing Adjustments

    • For creatinine clearance (CrCl) of 30-50 mL/min: administer 2.5 mg orally every other day.
    • For CrCl of 10-29 mL/min: reduce to 2.5 mg orally twice per week.

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    Test your knowledge on Levocetirizine with these flashcards. Explore key information such as brand name, drug class, and FDA indications. Perfect for pharmacy students or anyone interested in antihistamines.

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