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Questions and Answers
What is the brand name of Levocetirizine?
What class of drug is Levocetirizine?
Antihistamine
What are the common FDA indications for Levocetirizine?
Idiopathic urticaria, perennial, or seasonal allergic rhinitis
What is the mechanism of action (MOA) of Levocetirizine?
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Adjust Levocetirizine dosing when CrCl is _____ mL/min.
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For CrCl _____ mL/min, the dosage is 2.5 mg po twice per week.
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Study Notes
Levocetirizine Overview
- Brand Name: Xyzal
- Drug Class: Antihistamine
Indications
- Commonly prescribed for idiopathic urticaria.
- Effective for perennial allergic rhinitis.
- Utilized for seasonal allergic rhinitis.
Mechanism of Action
- Enantiomer of cetirizine, classified as a low-sedating antihistamine.
- Functions as a long-acting H1-receptor antagonist.
- Metabolite of hydroxyzine.
- Inhibits histamine’s interaction with H1 receptors, thereby halting the allergic response.
Renal Dosing Adjustments
- For creatinine clearance (CrCl) of 30-50 mL/min: administer 2.5 mg orally every other day.
- For CrCl of 10-29 mL/min: reduce to 2.5 mg orally twice per week.
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Description
Test your knowledge on Levocetirizine with these flashcards. Explore key information such as brand name, drug class, and FDA indications. Perfect for pharmacy students or anyone interested in antihistamines.
