Levey-Jennings Charts
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Questions and Answers

What is the Levey-Jennings Chart used to graph?

  • Successive QC results (correct)
  • Systematic errors
  • Test results
  • Analytical runs
  • What does good control results on a Levey-Jennings Chart look like?

  • Evenly distributed QC values about the mean and within +/- 1 SD limits (correct)
  • QC values within +2SD limits with no shifts or trends
  • QC values returning to within 2SD limit in the next run
  • Consecutive QC results within +2SD limits
  • What constitutes a systematic error shift on a Levey-Jennings Chart?

  • 6 consecutive results lying on the same side of the mean within +2SD limits (correct)
  • Consecutive QC results within +2SD limits moving in the same direction
  • Just 1 QC value outside 2SD but within 3SD limit
  • Gradual loss of reliability of the test system
  • When should an analytical run be rejected based on QC values?

    <p>If just 1 QC value is outside 2SD but within the 3SD limit</p> Signup and view all the answers

    What does a trend on a Levey-Jennings Chart indicate?

    <p>Gradual loss of reliability of the test system</p> Signup and view all the answers

    What is the main cause of a systematic error shift on a Levey-Jennings Chart?

    <p>Changes in reagent</p> Signup and view all the answers

    How many consecutive results lying on the same side of the mean indicate a systematic error shift on a Levey-Jennings Chart?

    <p>6</p> Signup and view all the answers

    In what situation should an analytical run not be rejected based on QC values on a Levey-Jennings Chart?

    <p>Just 1 QC value is outside 2SD but within the 3SD limit</p> Signup and view all the answers

    What does a trend on a Levey-Jennings Chart indicate?

    <p>Gradual loss of reliability of the test system</p> Signup and view all the answers

    When are test results still considered in-control on a Levey-Jennings Chart?

    <p>If QC values are within +2SD limits and there are no shifts or trends</p> Signup and view all the answers

    Study Notes

    Levey-Jennings Chart

    • Used to graph quality control (QC) data over time, allowing for the detection of trends and shifts in analytical performance.

    Good Control Results

    • Randomly scattered around the mean, with an equal number of points above and below the mean.
    • No systematic pattern or trends, indicating analytical performance is within acceptable limits.

    Systematic Error Shift

    • A consistent deviation from the mean, indicating a problem with the analytical process.
    • Constituted by 7 or more consecutive results lying on the same side of the mean.
    • Typically caused by a problem with the instrument, reagents, or analytical technique.

    Rejecting an Analytical Run

    • An analytical run should be rejected if the QC values exceed the acceptable limits or show a systematic error shift.
    • Rejection is necessary to prevent erroneous results from being reported.

    Trend Identification

    • A trend on a Levey-Jennings Chart indicates a gradual change in analytical performance over time.
    • May be due to instrument drift, reagent degradation, or other factors, and requires corrective action.

    Analytical Run Acceptance

    • An analytical run should not be rejected based on QC values if the results are within acceptable limits and show no systematic error shift.
    • Results are still considered in-control if the QC values are within the acceptable range and show no trends or shifts.

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    Description

    Test your knowledge of data handling and method evaluation with this quiz on Levey-Jennings charts. Learn about interpreting QC values, identifying shifts, and understanding systematic errors. Master the concepts necessary for ensuring accurate and reliable test results.

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