Levels of Organization in Histology

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What does the term 'histology' mean?

Study of tissues under a microscope

Why is studying the normal structure and function of tissues important?

To better understand the changes that occur during disease

Who was the first person to observe cells?

Robert Hooke

What is the main purpose of studying histology?

To correlate microscopic appearance with function in health and disease

Which branch of science involves prerequisites like Histology, Anatomy, and Pathology?

Pre-clinical Sciences

How is histology different from gross anatomy?

Histology involves studying cells under a microscope, while gross anatomy studies organs without magnification

What is the purpose of a biopsy?

To examine tissue taken from a living body

Which of the following is a basic sample preparation technique prior to histological analysis?

Fixing

In which level of organization would one study the microscopic details of tissues of different organs/organ systems?

General Histology

What does autopsy involve?

Examination of post-mortem tissue

Which technique involves dehydrating, clearing, and infiltrating tissue samples?

Processing

What type of examination is necropsy associated with?

Examination of tissue taken from a dead animal

What is the purpose of a bone marrow biopsy?

To detect ALK positive cells

In the context of cancer gene testing, which technique is specifically mentioned for detecting ALK positive cells?

Fluorescence in situ Hybridization (FISH)

In breast cancer gene testing, what is the specific gene mentioned for testing?

HER2

What does an IHC Score 0 indicate in the context of staining intensity?

No staining

In CML, what translocation is characteristic of the disease?

Translocation t(9;22)

What is the purpose of a blood smear or peripheral blood film in laboratory work?

To expose the morphology of peripheral blood cells

Robert Hooke was the first person to discover tissues.

False

Histology is the study of the microscopic anatomy of organs.

False

Understanding the normal structure and function of tissues is not important in interpreting disease changes.

False

Autopsy is commonly performed to study the microscopic details of tissues.

False

Correlating microscopic appearance with function is not relevant in health and disease.

False

The cell theory was proposed by Rudolf Virchow.

False

Autopsy involves examining post-mortem tissue.

True

Biopsy is an examination of tissue taken from a living body.

True

Necropsy is associated with the examination of tissue from dead animals.

True

Histological examination of tissues starts with necropsy in the case of animal tissues.

False

Studying histology involves the microscopic study of the 4 basic tissues.

True

Systemic Histology involves the microscopic study of the tissues of different organs and organ systems.

True

A bone marrow biopsy allows evaluation of the marrow's overall cellularity and detection of focal lesions only.

False

Peripheral blood film exposes the morphology of peripheral blood cells, making it essential for diagnosing primary blood diseases only.

False

ALK gene testing for lung cancer can be detected using Fluorescence in situ Hybridization (FISH) only.

False

An IHC Score of 3 indicates no staining in the context of staining intensity.

False

Necropsy involves the examination of tissues under a microscope to study their microscopic details.

False

The study of histology plays a fundamental role in understanding the correlation between microscopic appearance and function of tissues.

True

Test your knowledge on the different levels of organization in histology, from basic tissues to tissues of organs/organ systems. Learn about stratified epithelium, bone, cuboidal epithelium, and columnar epithelium.

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